新疆博斯腾湖沉积岩心的~(210)Pb、~(228)Th、~(239,240)Pu和~3H的分布及意义

作者测定了博斯腾湖沉积岩心~(210)Pb、~(228)Th和核试验释放核素~(239,240)Pu、~3H的分布,并据~(210)Pb、~(228)Th、~(239,240)Pu的结果估算湖泊的沉积速率,分别为0.31cm/a,0.26cm/a和0.33cm/a。它表明该湖泊近百年来沉积环境十分稳定。沉积物岩心极好地保存了人类大气核试验的历史记录。~(239,240)Pu分布在1963±2出现峰值,与60年代核试验高峰期相当吻合。沉积物孔隙水~3H分布的峰值出现在1969年,与湖水的混合过程有关。     

22nd IAS Meeting of Sedimentology

The 22nd IAS Meeting of Sedimentology was held in the Convention Centre of the Grand Hotel Adriatic, in a small touristic town Opatija, located on the eastern Adriatic coast where Central Europe and the Mediterranean meet. It was the second IAS Meeting held in Croatia--the first one, 4th IAS Regional Meeting of Sedimentology, was held in Split in 1983. The Meeting in Opatija was organized by the Institute of Geology (Zagreb) and the Croatian Geological Society. The sponsor was Ministry of Science and Technology of the Reoublic of Croatia.     

一定要把人类的牧地变成鲸类的墓地？

谁操纵了鲸类的命运 鲸（Whale），地球上现存最大型的动物，也是最大型的哺乳动物，曾经广泛分布在世界各大洋的海洋霸主，但它们在用现代科技武装起来的人类面前，再也强大不起来了。如今，徘徊在灭绝边缘的鲸类除了面临海洋污染、船舶撞击、噪声污染、渔业误捕和渔网缠绕等因素造成的危险外，更主要的威胁来自于捕鲸船的围猎。     

Mantle processes during ocean formation：Petrologic records in peridotites from the Alpine－Apennine ophiolites

Mantle peridotites were early exposed at the sea-floor of the Jurassic Tethys derived from the subcontinental mantle of the Europe-Adria system. During continental rifting and oceanic spreading, these lithospheric peri-dotites were percolated via diffuse reactive porous flowby melt fractions produced by near-fractional melting of the upwelling asthenosphere. Ascending melts inter-acted with the lower lithosphere, dissolving pyroxenes and precipitating olivine, and crystallized at shallower levels in the mantle column causing melt impregnation.Subsequent focused porous flow formed replacive dunitechannels, cutting the impregnated oeridotites, which were conduits for upward migration of MORB-type liq-uids. Melt migration produced depletionlrefertilization and significant heating of the percolatedlimpregnated mantle, i.e the thermochemical erosion of the litho-sphere. Impregnated and thermally modified lithos-pheric mantle was cooled by conductive heat loss dur-ing progressive lithosphere thinning and was intrudeaby MORB magmas, which formed Mg-rich and Fe-richgabbroic dykes and bodies. Alpine-Apennine ophiolitic peridotites record the deep-seated migration of melts which changed their compositions and dynamics during the rift evolution. The thermochemical erosion of the lithospheric mantle by the ascending asthenospheric melts, which induces significant compositional and rhe-ological changes in the lower lithosphere, is a major process in the evolution of the continent-ocean transi-tion towards a slow spreading oceanic system.     

基于生物信息学探讨骨质疏松症与2型糖尿病的关系

目的：基于生物信息学探讨骨质疏松症与 2 型糖尿病的关系。方法：通过基因表达汇编（GEO）数据库检索骨质疏松症和2型糖尿病的相关数据集,并筛选骨质疏松症-2型糖尿病共同差异表达基因,将数据导入STRING数据库找寻关键基因,以一个单细胞测序数据集作为检验集验证关键基因细胞层面的表达水平,对筛选结果进行基因本体（GO）功能及京都基因与基因组百科全书（KEGG）通路富集分析,并对关键靶点、相关中药进行频数统计及功效分类。结果：骨质疏松症与 2 型糖尿病相关通路集中在 ErbB信号通路、丝活化蛋白激酶（MAPK）信号通路、神经营养素信号通路、NOD样受体信号通路。频数统计结果显示,与骨质疏松症-2型糖尿病关键基因相关的中药有51味,以功效分类,可分为清热解毒药、止痛药、祛风药、补虚药、止呕药。结论：骨质疏松症和2型糖尿病都是复杂的代谢性疾病,涉及众多基因表达网络和信号通路。尽管两种疾病存在复杂的基因网络背景,但是分析结果表明两种疾病之间仍存在高度重合的差异基因表达和信号通路。这表明两种疾病的分子机制密切相关,可能存在共同调控的靶点,因此这些靶点可能成为药物同时干预两种疾病的治疗靶点。