深水铺管船托管架疲劳分析及动态监测点选取研究

作为S型铺管作业的关键性装备,托管架长期承受着交变载荷的作用,随着海洋开发向超深水发展,结构疲劳破坏问题不容忽视。采用疲劳谱分析的方法并结合线性累积损伤理论,对托管架结构频域下的变形进行了分析,计算了正常海况下和极端海况下托管架疲劳损伤度并对疲劳寿命进行了评估。研究发现托管架在正常海况下作业符合安全要求,在极端海况下局部结构会受到破坏。并从托管架结构安全监测角度,筛选了结构疲劳分析关键点位,为监测点位的选取提供了依据。     

The Latest Research Progress on El Nino

Cold water in the deep Pacific can be drawn up to the surface (or west warm water drifts eastwards ) because strong tide increases the mixing of seawater both in vertical and horizontal. In this way greenhouse effect is decreased or increased by means of absorbing (or releasing) CO2. Therefore, La Nina cold event (or El Nino warm event) may occur,which is caused by wanning - up or cooling - down air above the ocean. Volcanic action at sea bottom is also controlled by strong tide.     

高纯河豚毒素对蛙坐骨神经动作电位的影响

用电生理学方法观察了4种不同浓度的高纯河豚毒素(tetrodotoxin,TTX)对蛙离体坐骨神经动作电位的影响.实验结果表明:1μmol/dm3TTX在给药后7 min能显著抑制动作电位的上相幅度(P<0.05),但在给药后10 min才显著抑制动作电位的下相幅度(P<0.01);20μmol/dm3TTX在给药后3 min内能完全抑制动作电位的形成.1μmol/dm3TTX在给药后1~5min对动作电位传导速度的影响没有统计学意义,5μmol/dm3TTX在5min时可显著抑制传导速度(P<0.05),而10μmol/dm3TTX在2min时便显著抑制传导速度(P<0.05).实验结果提示高纯河豚毒素对蛙离体坐骨神经动作电位的影响存在剂量效应关系.     

富钴结壳分布的分形特征

利用我国在西太平洋国际海底两个海山获得的富钴结壳资料进行分形研究后发现，富钴结壳的分布具有变维分形分布的特点，结壳丰度呈二阶累计和分形分布，结壳厚度呈多阶不定累计和分形分布，通过计算得到了它们各自的分维数，进而对两个海山的结壳资源进行了初步评价。     

波浪作用下岸坡和海底平衡条件的研究

提出波浪作用下岸坡和海底动态和静态平衡条件的数学模型。在已建立的推移质泥沙体积输沙率基本关系式的基础上,根据连续方程,计算出底坡、泥沙、波浪三要素在动态和静态平衡情况下的关系式,得出反映这种关系的底坡平衡函数曲线图。用实际资料对这一函数曲线进行了验证,并对实际资料相对模型的某些差异作出解释。     

Research on Characteristics of Density Current Under the Action of Waves

In this paper,the characteristics of density current under the action of waves are describedwith the help of flume experiment and theoretical analysis.The study shows that turbid water under the ac-tion of the waves can present three types of motion,i.e.significant stratification,fragile stratification andstrong mixing.The motion of turbid water presents significant stratification when(H/D)/△ρ/ρ~(1/2)≤4.5,generally this state is known as density current.The formulas of motionvelocity,thickness,and discharge of density current moving on horizontal bottom are derived by use of ba-sic equations such as momemtum equation,equation of energy conservation and continuity equation offluid.The time-average velocity and the thickness of density current under the action of waves have a rela-tionship with such parameters as relative density(△ρ/ρ),wave height(H),and water depth(D).Whenthese parameters are determined,the time-average thickness and motion velocity of density current are al-so determined.The relat     

Fatigue Behavior of Plain Concrete Under Biaxial Compression: Experiments and Theoretical Model

The effects of different lateral confinement stress on the fatigue behavior of and cumulative damage to plain concrete are investigated experimentally. Eighty 100 mm x 100 mm x 100 mm specimens of ordinary strength concrete are tested under constant- or variable-amplitude fatigue loading and lateral confinement pressure in two orthogonal directions. A fatigue equation is developed by modifying the classical Aas-Jakobsen S-N equation for taking into account the effect of the confined stress on fatigue strength of plain concrete. The results of variable-amplitude fatigue tests indicate that the linear damage theory proposed by Palmgren and Miner is unreasonable in the biaxial stress state. A nonlinear cumulative damage model that could model the effects of the magnitude and sequence of variable-amplitude fatigue loading and lateral confinement pressure is proposed on the basis of the evolution laws of the residual strains in the longitudinal direction during fatigue tests. The residual fatigue life predic     

Three-dimensional numerical simulation of oblique wave action on vertical walls

1 Introduction A vertical wall is one of the typical maritime sheltering structures in the coastal region, which is mainly subjected to wave forces. It has been a com- mon engineering assumption adopted for design pur- poses that normally incident wave fo…     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

浪流作用下系泊船舶撞击力和系缆力试验研究

以某25万吨矿石码头工程为例,分别进行了单流、单浪和浪流共同作用下,系泊船舶撞击力和系缆力试验。研究了不同水位、不同船舶载度、不同浪流夹角,单流、单浪和浪流共同作用时对船舶撞击力和系缆力的影响。分析了该码头工程护舷和缆绳的布置情况,为工程设计提供了依据。