南极环境对考察队员儿茶酚胺含量的影响

报道了中国第八次南极考察队（长城站）队员赴南极前、居留南极及回国后尿、血浆的去甲肾上腺素（ＮＥ）和肾上腺素（Ｅ）含量变化,以探讨考察队员在居留南极期间普遍存在生理和心理变化的物质基础。结果表明：考察队员到达长城站２周时尿中ＮＥ急剧增高（与赴南极前相比Ｐ＜０．０５）,越冬后（居留南极１年２周）ＮＥ大幅度下降（与到达２周时相比Ｐ＜０．００１）,考察结束回国后ＮＥ恢复到赴南极前水平。尿中Ｅ含量在到达南极２周时同样显著升高,且增高幅度大于ＮＥ（与赴南极前比较Ｐ＜０．００１）,越冬后Ｅ水平比到达２周时有所降低（Ｐ＜０．０５）,回国后Ｅ水平没有恢复。提示,儿茶酚胺变化参与综合应激反应过程,Ｅ受心理影响大于生理因素。还发现部分考察队员惧怕抽血,故测定尿儿茶酚胺含量更切实可行。经酸化处理的尿样品在短期内温度（室温）对儿茶酚胺含量影响不大,因此,从南极实地取样返回国内检测及进行南极医学方面的研究完全可行。     

Changes of serum thyroid hormone and plasma catecholamine of 16 th and 17 th Chinese Expeditioners in Antarctic environment

The serum thyroid hormone and plasma catecholamine were examined in 18 male and 2 female members of the Chinese Antarctic Expedition (who spent the 2000 or 2001 austral winter at the Great Wall Station) . The changes of serum thyroid hormone i. e. total thyroxine (TT4) and free T4 (FT4) , total triodothyronine (TT3) and freeT3 ( FT3 ) , thyroid stimulating hormone ( TSH ) and plasma catecholamine, including norepinephrine (NE) , epinephrine ( E) and dopamine ( DA ) , were investigated by Chemoluminescence Immunoassay (CLIA) and High Performance Liquid Chromatography with electrochemical detection (HPLC-ECD) . Samples were taken at different time; (1)1 day before departure to Antarctica (16th expedition 1999/12/ 09; 17th expedition 2000/12/06). (2) 1 day after returned to China after living 54 weeks in Antarctica ( 16th expedition 2000/12/25 ; 17th expedition 2001/12/25 ). Comparing the data of before departure and returned, results showed that there was a significant decrease in the contents of TT4 (P <     

量子共振检测仪在南极医学研究中的应用初探

本研究应用量子共振检测仪 (QRS)一种基于量子分析技术的灵敏能量分析器 ,测定了 1 0名南极考察队员的生理和心理改变。在出发前 (BD)、南极居留 6月时 (AR)和居留一年返回后次日 (RE)分别采取头发进行磁场分析。测定生理和心理指标 :三碘甲状腺胺酸 (T3)、四碘甲状腺胺酸 (T4)、促甲状腺激素 (TSH)、抑郁、孤独、不容忍、压力 ,评分以正负数值表示。结果表明 ,AR和RE各项指标的量化值与BD基础值相比都明显下降 (p <0 .0 1 )。例如 ,抑郁 (平均值±标准误 , X±S X)为 :1 .1 0± 0 .80 (BD) ,- 8.3± 0 .30 (AR) ,- 7.7± 0 .36(RE) ;TSH为 :- 2 .2± 0 .92 (BD) , 9.4± 0 .45(AR) ,- 8.4± 0 .40 (RE)。QRS量化值的负向改变反映了功能的异常 ,这一初步结果证实了文献报道的在南极长期居留可引起甲状腺活动改变和心境失调。     

居留南极对考察队员血中甲状腺素和儿茶酚胺含量的影响

本文报道了中国第 1 6次南极考察队 (长城站 )队员赴南极前和在南极居留一年二周返回国内后 ,血中甲状腺素和儿茶酚胺含量的变化 ,以探讨考察队员在居留南极期间普遍存在的生理和心理变化的物质基础。 1 6次队 1 0名男性考察队员血样分别用化学发光法检测血清总甲状腺素 (TT3、TT4)和促甲状腺激素 (TSH)的含量 ,用高效液相色谱 -电化学法测定血浆中肾上腺素(E)、去甲肾上腺素 (NE)和多巴胺 (DA)的含量。结果表明 :长城站 1 6次队 1 0名男性考察队员赴南极前和在南极居留一年二周返回国内后相比 ,血清中甲状腺素TT3含量无显著性差异 ,TT4含量有非常显著性降低 (P <0 0 1 ) ,促甲状腺激素TSH含量有非常显著性升高 (P <0 0 1 ) ;血浆中的NE、DA含量无显著性差异 ,E的含量有显著性降低 (P <0 0 5 )。南极特殊环境对考察队员甲状腺功能具有减退作用 ;对肾上腺髓质E在血浆中含量有降低作用 ;甲状腺和肾上腺髓质系统共同参与南极综合应激反应 ,以调节机体与外界的平衡。     

A survey on changes of multiple humoral factors in Antarctic expedition members

ＡｓｕｒｖｅｙｏｎｃｈａｎｇｅｓｏｆｍｕｌｔｉｐｌｅｈｕｍｏｒａｌｆａｃｔｏｒｓｉｎＡｎｔａｒｃｔｉｃｅｘｐｅｄｉｔｉｏｎｍｅｍｂｅｒｓＸｕｅＱｕａｎｆｕ（薛全福）；ＺｈｕＧｕａｎｇｊｉｎ（朱广瑾）；ＣｈｅｎＸｉａｎｇｙｉｎ（陈祥银）；ＸｕＳｈｕｈｕ...     

Changes of serum thyroid hormone and plasma catecholamine of 16 th and 17 th Chinese Expeditioners in Antarctic environment

The serum thyroid hormone and plasma catecholamine were examined in 18 male and 2 female members of the Chinese Antarctic Expedition (who spent the 2000 or 2001 austral winter at the Great Wall Station) . The changes of serum thyroid hormone i. e. total thyroxine (TT4) and free T4 (FT4) , total triodothyronine (TT3) and freeT3 ( FT3 ) , thyroid stimulating hormone ( TSH ) and plasma catecholamine, including norepinephrine (NE) , epinephrine ( E) and dopamine ( DA ) , were investigated by Chemoluminescence Immunoassay (CLIA) and High Performance Liquid Chromatography with electrochemical detection (HPLC-ECD) . Samples were taken at different time; (1)1 day before departure to Antarctica (16th expedition 1999/12/ 09; 17th expedition 2000/12/06). (2) 1 day after returned to China after living 54 weeks in Antarctica ( 16th expedition 2000/12/25 ; 17th expedition 2001/12/25 ). Comparing the data of before departure and returned, results showed that there was a significant decrease in the contents of TT4 (P <