参附注射液建立自发性高血压病大鼠肝阳上亢证模型的研究

目的：探讨参附注射液建立自发性高血压大鼠（SHR）模型的可能性。方法：将30只3月龄SPF级健康雄性自发性高血压大鼠称重，随机分为SHR组，附子汤组，参附注射液低、中、高剂量组，每组6只。各组采用对应药物灌胃进行模型制备，另取同品系同周龄雄性魏-凯二氏大鼠（WKY）6只作为正常对照组（WKY组）。观察参附注射液对SHR大鼠24h饮水量、易激惹程度、痛阈、睑结膜充血及收缩压的影响。结果：附子汤组及参附注射液中、高剂量组造模后均出现了易激惹程度增高、睑结膜充血程度增高、饮水量增多、痛阈降低、收缩压升高等肝阳上亢的表现，与WKY组及SHR组比较，差异有统计学意义（P<0.05)，表明造模成功。结论：参附注射液可以制备新型高血压肝阳上亢证模型，但是具体造模机制以及造模药物用量需待进一步探讨确定。     

基于卫星遥感数据的森林病虫害监测与评价

森林病虫害由于在森林资源中造成的重大破坏而被人们称为“不冒烟的火灾”,其对生态系统的研究具有重要意义。现有基于遥感数据的病虫害研究多集中在森林病虫害的监测、爆发原因以及发病区域内生产力的变化情况,而对于森林病虫害发生后森林中植被指数与叶面积指数之间的相关性的变化情况还相对较少,处于需要持续性深入探讨的阶段。以加拿大不列颠哥伦比亚地区2002—2012年森林病虫害数据为基础,分析不同严重程度的病虫害对叶面积指数（LAI）与归一化植被指数（NDVI）和增强型植被指数（EVI）的影响。结果表明：① 受病虫害感染的像元在轻度（Light）、中度（Moderate）和重度（Severe）三个严重级别中,NDVI与LAI之间的相关性由弱变强,又由强变弱;② EVI与LAI之间的相关性,在轻度（Light）、中度（Moderate）和重度（Severe）三个严重级别的像元中则依次变强。这一研究将为今后利用遥感数据识别病虫害、评价生态系统影响提供基础。     

Retrieving volume FeO and TiO_2 abundances of lunar regolith with CE-2 CELMS data using BPNN method

The volume FeO and TiO_2 abundances(FTAs) of lunar regolith can be more important for understanding the geological evolution of the Moon compared to the optical and gamma-ray results. In this paper, the volume FTAs are retrieved with microwave sounder(CELMS) data from the Chang'E-2 satellite using the back propagation neural network(BPNN) method. Firstly, a three-layered BPNN network with five-dimensional input is constructed by taking nonlinearity into account. Then, the brightness temperature(TB) and surface slope are set as the inputs and the volume FTAs are set as the outputs of the BPNN network.Thereafter, the BPNN network is trained with the corresponding parameters collected from Apollo, Luna,and Surveyor missions. Finally, the volume FTAs are retrieved with the trained BPNN network using the four-channel TBderived from the CELMS data and the surface slope estimated from Lunar Orbiter Laser Altimeter(LOLA) data. The rationality of the retrieved FTAs is verified by comparing with the Clementine UV-VIS results and Lunar Prospector(LP) GRS results. The retrieved volume FTAs enable us to re-evaluate the geological features of the lunar surface. Several important results are as follows. Firstly, very-low-Ti(1.5 wt.%) basalts are the most spatially abundant, and the surfaces with TiO_2 5 wt.% constitute less than 10% of the maria. Also, two linear relationships occur between the FeO abundance(FA) and the TiO_2 abundance before and after the threshold, 16 wt.% for FA. Secondly, a new perspective on mare volcanism is derived with the volume FTAs in several important mare basins, although this conclusion should be verified with more sources of data. Thirdly, FTAs in the lunar regolith change with depth to the uppermost surface,and the change is complex over the lunar surface. Finally, the distribution of volume FTAs hints that the highlands crust is probably homogeneous, at least in terms of the microwave thermophysical parameters.     

Complete nuclear ribosomal DNA sequence analyses of the black-footed abalone Haliotis iris

The black-footed abalone Haliotis iris is an economically important shellfish species in New Zealand. We successfully amplified, sequenced and analysed the complete nuclear ribosomal DNA (nrDNA) of H. iris. The length of the nrDNA was determined to be around 9.6?kb and included, in order, small subunit ribosomal RNA (nrSSU, 1858bp), internal transcribed spacer (ITS, 749?bp), large subunit ribosomal RNA (nrLSU, 3412bp) and an intergenic spacer (IGS, 3560–3662?bp). The nrLSU genes were identical in two individuals, whereas the nrSSU and ITS regions existed at three and four base differences, respectively. The IGS was more variable than the other nrDNA regions. A phylogenetic tree was constructed based on the ITS sequence datasets, which revealed that Haliotidae has two major subclades, mainly distributed in the North Pacific, Europe and Australia. The complete nrDNA sequence will be useful for the classification, phylogeny and breeding of this shellfish.     

基于概率积分法的采动坡体稳定性预测与分析

地下采煤会引起地表沉降、变形,甚至引发山体、河堤滑坡等地质灾害。采动坡体的稳定性研究一直是采矿工程中实际关心的问题。该文首先介绍分析了概率积分法移动变形稳态、动态预测模型以及基于极限平衡理论的单滑面采动坡体稳定性预测模型,提出了使用概率积分法结合Knothe时间函数对采动坡体稳定性进行预测分析的方法,并使用C#及XML Schema语言编制了相关的计算程序。最后,结合一个工程实例对采动坡体稳定性和动态变化过程进行了预测与分析,通过实测数据验证了提出方法的可行性,得出了采动引起的坡体下沉是影响坡体稳定性的主要因素,并提出了在坡体拉伸阶段进行注浆加固的方法。     

秦皇岛近岸海域绿藻微观繁殖体的分布以及在绿潮形成中的作用

2015年以来，秦皇岛近岸海域暴发了绿潮，对北戴河旅游区的环境和生态系统造成了严重影响。绿藻微观繁殖体在绿潮的形成过程中起到重要作用，主要包括孢子、配子、幼苗和营养片段。绿藻微观繁殖体作为绿潮的“种源”，其分布规律可以反映绿潮的“藻源”位置。本研究于2016年4-9月和2017年1月对秦皇岛近岸海域绿藻微观繁殖体的调查，探究了其分布规律以及生物量变化。结果显示，绿藻微观繁殖体主要分布在近岸海域，由近岸向远岸海域逐渐降低。绿藻微观繁殖体的数量在7、8月份最高，在冬季最低。受绿潮影响严重的海域微观繁殖体数量高于其它海域。秦皇岛近岸海域的绿藻微观繁殖体为该海域绿潮的种源，其分布规律表明秦皇岛近岸海域绿潮起源于本地。     

两株南极枝孢霉属真菌Cladosporium sp.NJF4和NJF6的次级代谢产物研究

南极因其独特的自然环境成为潜在、重要的微生物资源库,是产生新型生物活性物质和先导化合物菌株的潜在种源地,南极微生物正在成为创新药物研究新的重要资源。虽然近年来对南极微生物次级代谢产物的研究逐渐增加,但与温带和热带微生物研究相比仍处于初级阶段。对从南极普里兹湾海洋沉积物中获得的两株枝孢霉属真菌Cladosporium sp. NJF4和NJF6进行次级代谢产物分离及结构鉴定,获得20个化合物。化合物结构类型包括甾醇(1)、倍半萜类(7—8)、生物碱类(9—14)、二酮哌嗪(2—5、15—17)、芳香酸(6、18—19)等,其中倍半萜类(7—8)为首次从枝孢霉属真菌中分离得到,以上研究将为丰富南极微生物次级代谢产物库奠定一定的研究基础。     

Influence of Stress on Void Ratios of Compacted Crushed Rock Masses in Coal Mine Gobs

The transfer and evolution of stress among rock blocks directly change the void ratios of crushed rock masses and affect the flow of methane in coal mine gobs. In this study, a Lagrange framework and a discrete element method, along with the soft-sphere model and EDEM numerical software, were used. The compaction processes of rock blocks with diameters of 0.6, 0.8, and 1.0 m were simulated with the degrees of compression set at 0%, 5%, 10%, 15%, 20%, and 25%. This study examines the influence of stress on void ratios of compacted crushed rock masses in coal mine gobs. The results showed that stress was mainly transmitted downward through strong force chains. As the degree of compression increased, the strong force chains extended downward, which resulted in the stress at the upper rock mass to become significantly higher than that at the lower rock mass. It was determined that under different degrees of compression, the rock mass of coal mine gobs could be divided, from the bottom to the top, into a lower insufficient compression zone (ICZ) and an upper sufficient compression zone (SCZ). From bottom to top, the void ratios in the ICZ sharply decreased and those in the SCZ slowly decreased. Void ratios in the ICZ were 1.2–1.7 times higher than those in the SCZ.

     

The relationship between the semi-major axis, mass index and age of the Leonid meteor shower

Owing to sublimation of ice, comet nuclei eject dust particles when they are near to the sun. Those particles assume velocities and then vary their orbits to ones similar to that of the comet. The most notable difference between the orbit of the parent comet and those of the particles is their semi-major axes. This difference (Δ a ) has been widely used in modern meteor shower predictions. Observational evidence of the distribution showed that it is a function of Δ a , and the age of the dust trail. However, the relation is not well known. In this paper, a simplified relation between Δ a , the mass index ( s ) and the age of the dust trail is presented, taking the instance of a recent Leonid meteor shower.