双因素判别分析胃癌组织与正常组织自体荧光光谱

通过对手术切除的37例胃癌患者的离体标本的自体荧光光谱检测,显示308nm,337nm激发光谱均呈双主峰结构,双主峰的比值均能区分胃癌与正常胃壁(P<0.001).分别用308nm,337nm激发荧光光谱单因素分析诊断胃癌的灵敏度、特异度、阳性预测值分别为88.8%,86.8%,86.4%和80.1%,72.1%,67.5%.对308nm及337nm激发荧光光谱双因素分析,癌诊断的灵敏度、特异度、阳性预测值分别为94.4%,92.1%,91.9%,其诊断正确符合率明显高于单因素分析的结果.研究表明,以308nm及337nm双波长激发检测胃壁浆膜,双因素判别算法可较好地区分胃癌,这种方法有望成为手术中快速识别胃癌在胃壁的浸润范围的有效方法.     

PLS-ANN分析血浆自体荧光光谱的二阶导数光谱识别胃癌

探讨偏最小二乘法结合神经网络法(简称PLS-ANN)分析血浆自体荧光光谱的二阶导数光谱识别胃癌的优势,对20例胃癌病人和23例健康人血浆进行以405nm为激发光的自体荧光光谱检测,采用PLS-ANN法分别对血浆自体荧光光谱和二阶导数光谱进行判别分析。PLS-ANN分析血浆的自体荧光光谱法诊断胃癌的灵敏度为75%,特异度为83%,准确率为79%,PLS-ANN分析血浆的二阶导数光谱法诊断胃癌的灵敏度为90%,特异度为96%,准确率为93%。结果表明PLS-ANN分析血浆的二阶导数光谱法识别胃癌,优于PLS-ANN分析血浆的自体荧光光谱法,有望成为快速识别胃癌的较理想方法。     

海洋对白垩纪——第三纪碰撞的振荡反应

海洋对白垩纪—第三纪碰撞的振荡反应ＳｔｅｖｅｎＤ’Ｈｏｎｄｔ等白垩纪—第三纪（Ｋ—Ｔ）碰撞对海洋和气候产生的长期影响鲜为人知，过去的研究往往用相隔很远的样品来估计海洋一气候系统碰撞前后的平均状态，其研究结果并未提供什么证据来说明长期的物理变化起因于Ｋ...     

Marine mammals from northeast Atlantic: relationship between their trophic status as determined by delta13C and delta15N measurements and their trace metal concentrations

The relationship between trophic position through delta13C and delta15N and trace metal concentrations (Zn, Cd, Cu and Hg) was investigated in the tissues of six marine mammal species from the Northeast Atlantic: striped dolphin Stenella coeruleoalba, common dolphin, Delphinus delphis, Atlantic white-sided dolphin Lagenorhynchus acutus, harbour porpoise Phocoena phocoena, white beaked-dolphin Lagenorhynchus albirostris, grey seal Halichoerus grypus stranded on French Channel and Irish coasts. White-beaked dolphins, harbour porpoises, white-sided dolphins, common and striped dolphins display the same relative and decreasing trophic position, as measured by delta15N values, along both the Irish and French channel coasts, reflecting conservative trophic habits between these two places. Hepatic and renal Cd concentrations were significantly correlated to muscle delta13C and delta15N values while Hg, Zn and Cu did not. These results suggest that Cd accumulation is partly linked to the diet while other factors such as age or body condition might explain Hg, Zn or Cu variability in marine mammals. Combined stable isotope and trace metal analyses appear to be useful tools for the study of marine mammal ecology.     

冀东马兰峪背斜南翼与西部倾伏端盖层变形特征及其构造意义

燕山中部冀东遵化、迁西、青龙一带以太古宇深变质结晶岩系为核部的东西向构造形迹长期以来被认为是一个复式背斜构造,近年来又有学者提出它是一个中生代变质核杂岩。这2种不同认识涉及到华北克拉通北部中生代区域大地构造演化和稳定克拉通内部大型基底结晶岩系的剥露机制问题。对马兰峪背斜南翼和西部倾伏端盖层岩系开展的详细构造研究表明,变形总体表现为连续的褶皱变形及伴生的逆冲构造;构造样式表现为基底卷入式的厚皮构造与盖层内部软弱岩系控制的薄皮构造共存的特征;变形机制表现为顺层挤压导致的纵弯弯曲和相关的断裂构造;近南北向的缩短率介于16%～27%之间。盖层岩系中未发现变质核杂岩构造模型所预期的系列高角度正断层。基底与盖层不整合面接触带尽管在后期构造变形过程中曾经发生过局部的差异性滑动,但并不是造成大规模构造剥蚀和地壳柱切失的剥离断层。因此,冀东马兰峪背斜不是中生代的变质核杂岩,而是水平挤压背景下基底结晶岩系与盖层共同卷入纵弯褶皱变形的厚皮式褶皱构造。     

A new approach for detecting and mapping sewage impacts

Increased nitrogen loading has been implicated in eutrophication occurrences worldwide. Much of this loading is attributable to the growing human population along the world's coastlines. A significant component of this nitrogen input is from sewage effluent, and delineation of the distribution and biological impact of sewage-derived nitrogen is becoming increasingly important. Here, we show a technique that identifies the source, extent and fate of biologically available sewage nitrogen in coastal marine ecosystems. This method is based on the uptake of sewage nitrogen by marine plants and subsequent analysis of the sewage signature (elevated delta 15N) in plant tissues. Spatial analysis is used to create maps of delta 15N and establish coefficient of variation estimates of the mapped values. We show elevated delta 15N levels in marine plants near sewage outfalls in Moreton Bay, Australia, a semi-enclosed bay receiving multiple sewage inputs. These maps of sewage nitrogen distribution are being used to direct nutrient reduction strategies in the region and will assist in monitoring the effectiveness of environmental protection measures.     

国防气象卫星计划中的微波成像仪／探测器专用传感器（SSMIS）

1.引言国防气象卫星计划(DMSP)打算在Block 5D-3卫星上装备一套空气喷气电子系统部目前正在设计和制造的微波成像仪/探测器专用传感器(SSMIS).空气喷气电子系统部还负责SSMIS上行链路飞行软件和包括反演算法的SSMIS地面处理软件的设计和开发.SSMIS将提供低层大气温度廓线和湿度廓线、高层大气温度廓线,以及12个附加的环境参数,包括海洋风速、降     

Recharge estimation for transient ground water modeling

Reliable ground water models require both an accurate physical representation of the system and appropriate boundary conditions. While physical attributes are generally considered static, boundary conditions, such as ground water recharge rates, can be highly variable in both space and time. A practical methodology incorporating the hydrologic model HELP3 in conjunction with a geographic information system was developed to generate a physically based and highly detailed recharge boundary condition for ground water modeling. The approach uses daily precipitation and temperature records in addition to land use/land cover and soils data. The importance of the method in transient ground water modeling is demonstrated by applying it to a MODFLOW modeling study in New Jersey. In addition to improved model calibration, the results from the study clearly indicate the importance of using a physically based and highly detailed recharge boundary condition in ground water quality modeling, where the detailed knowledge of the evolution of the ground water flowpaths is imperative. The simulated water table is within 0.5 m of the observed values using the method, while the water levels can differ by as much as 2 m using uniform recharge conditions. The results also show that the combination of temperature and precipitation plays an important role in the amount and timing of recharge in cooler climates. A sensitivity analysis further reveals that increasing the leaf area index, the evaporative zone depth, or the curve number in the model will result in decreased recharge rates over time, with the curve number having the greatest impact.