Abstract: | The Actinomycetes strain of the genus Rhodococcus having been isolated from the river Saale is able to use phenol as the sole carbon source up to concentrations of 2 g/l and metabolizes phenol via the β-ketoadipic acid path (ortho-cleavage). The synthesis of the inducable enzyme system can be inhibited by chloramphenicol. In detailed experiments in discontinuous and continuous cultures the growth rate and the yield coefficient attain their maxima of 0.256 h?1 and 0.62, resp., at phenol concentrations of 0.5 … 0.8 g/l. At higher substrate concentrations there occurs a substrate inhibition. In the range between 20 and 40°C growth and phenol utilization are highly dependent on temperature. |