| 二色桌片参的化学成分研究Ⅲ。二色桌片参多糖-1－岩藻聚糖的免疫调节作用 |
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| 引用本文： | 黄益丽,郑忠辉,苏文金,陈福,吴萍茹,方金瑞.二色桌片参的化学成分研究Ⅲ。二色桌片参多糖-1－岩藻聚糖的免疫调节作用[J].海洋通报,2001,20(1). |
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| 作者姓名： | 黄益丽 郑忠辉 苏文金 陈福 吴萍茹 方金瑞 |
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| 作者单位： | 1. 厦门大学肿瘤细胞工程国家专业实验室,
2. 福建海洋研究所, |
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| 摘 要： | 研究了二色桌片参多糖-1(PMI-1)在体内、体外的免疫调节作用。结果表明，二色桌片参多糖-1体外能促进小鼠脾淋巴细胞增殖，促进小鼠脾淋巴细胞分泌IL-2：体内能显著促进迟发型超敏反应，增加脾指数、胸腺指数；具有显著的免疫增强作用。
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| 关 键 词： | 二色桌片参多糖免疫调节IL-2迟发型超敏反应 |
Studies on the Chemical Composition of Sea Cucumber Mensamaria Intercedens Ⅲ. Immunomodulative Effects of PMI-1 |
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| HUANG Yili,Zheng Zhonghui,SU Wenjin,Chen Fu,Wu Pingru,Fang Jinrui.Studies on the Chemical Composition of Sea Cucumber Mensamaria Intercedens Ⅲ. Immunomodulative Effects of PMI-1[J].Marine Science Bulletin,2001,20(1). |
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| Authors: | HUANG Yili Zheng Zhonghui SU Wenjin Chen Fu Wu Pingru Fang Jinrui |
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| Abstract: | The immunoactivities of PMI-1 are studied in vivo and in vitro. PMI-1(5、 50、 100ц g/mL ) in vitro could promote the proliferation of mice lymphocyte, and increase IL-2 production as well. In vivo, PMI-I could significantly improve the delayed-type hypersensitivity (DTH) degree and the weights of spleen and thymus, although it has little effect on the production of hemolysin antibodies. The results indicate that PMI-1 could remarkedly enhance the immunofunction in mice. |
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