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CT扫描层厚和增强对I期非小细胞肺癌形态学测量的影响
引用本文:李靖煦,关玉宝,夏亭亭,朱巧洪,林翰菲,曾庆思,李宏,孙申申,康雁.CT扫描层厚和增强对I期非小细胞肺癌形态学测量的影响[J].CT理论与应用研究,2013(4):659-664.
作者姓名:李靖煦  关玉宝  夏亭亭  朱巧洪  林翰菲  曾庆思  李宏  孙申申  康雁
作者单位:[1]广州医科大学附属第一医院,广州510120 [2]东北大学中荷生物医学与信息学院,沈阳110819
基金项目:广东省医学科研基金项目(A2010237).
摘    要:目的:探讨CT扫描层厚、增强与否对I期非小细胞肺癌(NSCLC)三维最大径、体积及质量的影响。方法:92例I期NSCLC患者,其中76例在平扫基础上进行了增强扫描;扫描数据传至CT后处理工作站,采用计算机辅助诊断软件描绘并分割病灶,分别自动测量2nlm、7inn层厚及7nlm增强前后病灶的最大径d(mm)、体积V(mm3)、质量m(g),计算各均值及方差,运用配对T检验评价不同层厚、增强与否对肿瘤的三维测量结果有无统计学差异。结果:2into、7mm层厚CT扫描条件下,d、玖m的测量结果具有显著统计学差异(P〈0.05);7mm层厚扫描条件下,cT增强前后d、V的测量无显著统计学差异(P〉0.05),m的测量具有显著统计学差异(P〈0.05)。结论:胸部cT扫描2mm、7mm层厚的选取对I期NSCLC三维最大径、体积及质量的测量结果具有一定的影响;CT增强可影响肿瘤的质量测量评价。

关 键 词:非小细胞肺癌  定量CT  层厚  增强  形态学

Effect of CT Section Thickness and Enhancement on Morphology of Stage I Non-Small Cell Lung Cancer
LI Jing-xu,GUAN Yu-bao,XIA Ting-ting,ZHU Qiao-hong,LIN Han-fei,ZENG Qing-si,LI Hong,SUN Shen-shen,KANG Yan.Effect of CT Section Thickness and Enhancement on Morphology of Stage I Non-Small Cell Lung Cancer[J].Computerized Tomography Theory and Applications,2013(4):659-664.
Authors:LI Jing-xu  GUAN Yu-bao  XIA Ting-ting  ZHU Qiao-hong  LIN Han-fei  ZENG Qing-si  LI Hong  SUN Shen-shen  KANG Yan
Institution:(The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China)
Abstract:Objective: To assess the effect of computed tomographic (CT) section thickness, CT enhancement on stage I non-small cell lung cancer (NSCLC) measurements calculated with three-dimensional methods. Methods: 92 patients of the stage ] NSCLC were analyzed on CT scan with 2 mm, 7 mm CT section thickness; of which 76 had 7 mm CT section thickness enhanced scanning. The data were sent to the CT post-processing workstation, the lesions were automatically delineated by using computer-aided diagnostic software. The maximum diameter: d (ram), volume: V (mm3), mass: rn (g) of the lesions were measured on each section thickness, before and after enhancement. Means and variances were calculated, and the differences across the two section thicknesses, before and after enhancement were studied by using pair T-test. Results: Differences in the means of d, V, m were significant between a section thickness of 2 and 7 mm (P 〈 0.05); Differences in the means of d, V were not significant between 7 mm plain CT and contrast enhancement (P 〉 0.05), while differences in the means of m were significant (P 〈 0.05). Conclusion: Section thickness of 2 and 7 mm selection on chest CT scan had a certain influence on maximum diameter, volume and mass measurement result of stage I NSCLC; CT enhancement could affect measurement result of mass.
Keywords:non-small cell lung cancer  quantitative CT  section thickness  enhancement  morphology
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