| 除草剂丁草胺对黄鳝的遗传毒性 |
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| 引用本文： | 胡庚东,陈家长,吴伟,瞿建宏,范立民,吴进才. 除草剂丁草胺对黄鳝的遗传毒性[J]. 广东海洋大学学报, 2005, 25(1): 43-46 |
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| 作者姓名： | 胡庚东 陈家长 吴伟 瞿建宏 范立民 吴进才 |
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| 作者单位： | 1. 中国水产科学研究院淡水渔业研究中心,江苏,无锡,214081
2. 扬州大学农学院,江苏,扬州,225009 |
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| 摘 要： | 通过分析红细胞微核、核异常及染色体数目和结构畸变,研究了除草剂丁草胺对黄鳝细胞的遗传毒性。采用腹腔注射的方法染毒,质量分数分别为0. 05、0 .08和0. 12mg/kg,结果(经t检验)表明除草剂丁草胺在较低浓度时( <0. 05mg/kg)基本上不表现诱变性,但0. 12mg/kg浓度组可显著地提高黄鳝外周血红细胞的微核率(P<0 .01),对黄鳝染色体数目畸变率和结构畸变率也有影响(P<0 .01)。这表明除草剂丁草胺在一定浓度范围内对黄鳝具有明显的遗传学损伤作用。
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| 关 键 词： | 黄鳝 丁草胺 遗传毒性 微核 染色体畸变 |
| 文章编号： | 1007-7995(2005)01-0043-4 |
| 修稿时间： | 2004-07-30 |
Mutagenesis of Butachlor to Cells of Monopterus albus |
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| HU Geng-dong,CHEN Jia-zhang,WU Wei,QU Jian-hong,FAN Li-min,WU Jin-cai. Mutagenesis of Butachlor to Cells of Monopterus albus[J]. Journal of Zhanjiang Ocean University, 2005, 25(1): 43-46 |
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| Authors: | HU Geng-dong CHEN Jia-zhang WU Wei QU Jian-hong FAN Li-min WU Jin-cai |
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| Abstract: | The authors studied the genetic toxicity of Butachlor to the cells of Monopterus albus by analyzing micronulei, structural chromosomal and numerical aberrations. The Butachlor was intraperitoneally injected into Monopterus albus with the dosage of 0.05 mg/kg, 0.08 mg/kg and 0.12 mg/kg, respectively. The results (tested by t test) show that Butachlor in 0.05 mg/kg does not affect the rates of micronulenus, structural chromosomal and numerical aberrations. Butachlor in 0.12 mg/kg can increase the rates of micronulenus, structural chromosomal and numerical aberrations. It suggests that the Butachlor can cause significant genetic damage to the cells of Monopterus albus. |
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| Keywords: | Monopterus albus Butachlor genetic toxicity micronuclenus chromosomal aberration |
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