四川省盐亭县食管癌高发与环境地球化学关系

四川省盐亭县是中国著名的食管癌高发区。临床医学对癌变组织、血液等人体组织的研究发现Mn、Mo、Se和Zn 4种元素的缺乏与食管癌关系最为密切。为了探讨食管癌与饮食等环境因素的关系,选择发病率有明显差异的盐亭县高发村和低发村,分别采集分析蔬菜、粮食、土壤等环境介质中微量元素含量,并估算了盐亭县居民Mn、Mo、Se和Zn的日摄入量。结果表明:盐亭县居民Mn和Mo的日摄入量适宜,Se和Zn的日摄入量偏低。但由于食管癌高发村、低发村居民日摄入量没有显著差别,因此,造成研究区食管癌高发的确切原因还有待于进一步研究。

Relationship between Esophageal Cancer and Environmental Geochemistry in Yanting County,Sichuan Province

Yanting County,Sichuan Province is the high incidence area of esophageal cancer.The relationships between deficiency of trace elements(e.g.Mn,Mo,Se and Zn) and occurrence of esophageal cancer have been found in medical studies.In order to discuss the relationships between esophageal cancer and environmental elements(e.g.diet and so on),vegetables,grains and soils were collected and analysed for Mn,Mo,Se and Zn in high-and low-incidence villages,Yanting Country.Furthermore,daily intakes of Mn,Mo,Se,and Zn were estimated for residents in Yanting County.Results reveal that daily intakes of Mn and Mo are moderate,whereas those of Se and Zn are lack in all the villages.Due to the similarity of daily intakes between high-and low-incidence villages,the physical cause of severity of esophageal cancer in Yanting County need to be further researched in the future.