贻贝对麻痹性贝类毒素的蓄积代谢研究进展

麻痹性贝类毒素(paralytic shellfish toxins,PSTs)能够导致贝类、鱼类等海洋生物染毒或死亡,危害海洋生态安全及人类健康.其中,贻贝具有强蓄积性特点,在国外可作为PSTs的指示性生物.近年来,我国因食用贻贝造成多起PSTs中毒事件成为安全关注重点,因此急需弄清其风险形成机理.本文通过综述我国近...

Research progress on the accumulation and metabolism of paralytic shellfish toxin in mussels

Poisoning with paralysis shellfish toxins (PSTs) can cause death in shellfish, other fish, and other marine organisms as well as hamper the marine ecology and human health. Mussels are highly accumulative and serve as indicators of PSTs in foreign countries. In recent years, several cases of PST poisoning by mussel consumption in China have become the focus of safety attention. Therefore, understanding the mechanism of risk formation is essential and urgent. This study evaluates the risk degree of PSTs in offshore mussels and other shellfishes in China and the accumulation effect of mussels on PSTs from different toxigenic alga sources, analyzes the influence of environmental factors on the accumulation and metabolism, and explores in depth the specificity of mussel accumulation and metabolism. Furthermore, focusing on the expression regulation process of the mussel metabolic stage, our study clarifies the influencing factors, transformation functions, and modes. In future studies, we aim to focus on understanding the basic risk rule and change process of PSTs in mussels as well as other marine shellfish in certain target areas of China and establish regional risk prevention and control technology for active prevention and control of PST risk in mussels of China. This will contribute positively and significantly toward protecting consumer health and the marine ecology.