Interaction of CYP1A1 inducers in liver of rainbow trout and eelpout |
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Authors: | D. Ronisz,L. F rlin |
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Affiliation: | D. Ronisz,L. Förlin |
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Abstract: | The hepatic CYP1A1 (ethoxyresorufin-O-deethylase (EROD) and protein level) in rainbow trout and eelpout was induced by isosafrole, β-naphthoflavone, 3,3′,4,4′-tetrachlorobiphenyl and mixtures of two of the compounds. A potentiation effect of the CYP1A1 response was observed when isosafrole was given together with β-naphthoflavone, but not when isosafrole was given with 3,3′,4,4′-tetrachlorobiphenyl. |
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