Lysosomal and lipid-associated parameters in the livers of three species of arctic seabird chicks: species differences and relationships with contaminant levels |
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Authors: | Hegseth Marit Nøst Regoli Francesco Gorbi Stefania Bocchetti Raffaella Gabrielsen Geir Wing Camus Lionel |
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Institution: | a Akvaplan-NIVA AS, Fram Centre - High North Research Centre for Climate and the Environment, 9296 Tromsø, Norway b University of Tromsø, Brevika, 9037 Tromsø, Norway c Universita Polytechnica delle Marche, Facolta di Scienze, Via Brecce Bianche, 60131 Ancona, Italy d Norwegian Polar Institute, Fram Centre - High North Research Centre for Climate and the Environment, 9296 Tromsø, Norway |
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Abstract: | Lysosomal membrane stability, lipofuscin (LF), malondialdehyde (MDA), neutral lipid (NL) levels, as well as halogenated organic compounds (HOCs), Cr, Cd, Pb and Fe concentrations were analyzed in liver of black-legged kittiwake (BK), herring gull (HG), and northern fulmar (NF) chicks. There were significant species differences in the levels of NL, LF and lysosomal membrane stability. These parameters were not associated with the respective HOC concentrations. LF accumulation was associated with increasing Cr, Cd and Pb concentrations. HG presented the lowest lysosomal membrane stability and the highest.LF and NL levels, which indicated impaired lysosomes in HG compared to NF and BK. Lipid peroxidation was associated with HOC and Fe2+ levels. Specific HOCs showed positive and significant correlations with MDA levels in HG. The study indicates that contaminant exposure can affect lysosomal and lipid associated parameters in seabird chicks even at low exposure levels. These parameters may be suitable markers of contaminant induced stress in arctic seabirds. |
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