| 硬骨鱼类神经内分泌-免疫网络及其调控研究 |
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| 引用本文： | 温海深,高玲,李文阁.硬骨鱼类神经内分泌-免疫网络及其调控研究[J].中国海洋大学学报(自然科学版),2006,36(1):60-64. |
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| 作者姓名： | 温海深 高玲 李文阁 |
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| 作者单位： | 1. 中国海洋大学水产学院,山东,青岛,266003
2. 内蒙古民族大学,内蒙古,通辽,028042 |
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| 基金项目： | 农业部重点实验室基金;农业部重点实验室基金 |
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| 摘 要： | 综述了近10余年来国内外有关硬骨鱼类神经内分泌-免疫网络(N-E-IN)及其调控的研究概况。以下丘脑-垂体-肾间组织(HPI)轴为核心,阐述了下丘脑肽类激素、垂体激素、糖皮质醇(GC)、性类固醇激素(sexual steroid)对鱼类免疫功能的调节,环境胁迫(stress)对鱼类(N-E-IN)的影响,细胞因子(cytokine)对硬骨鱼类内分泌功能的影响,展望了今后该领域的研究方向。
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| 关 键 词： | 鱼类 内分泌 免疫 |
| 文章编号： | 1672-5174(2006)01-060-05 |
| 收稿时间： | 2005-07-04 |
| 修稿时间： | 2005-10-20 |
Studies on the Neur-Endocrin-lmmunoregulatory Network (N-E-IN) and Its Regulation/Control Mechanism in Teleosts |
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| WEN Hai-Shen,GAO Ling,LI Wen-Ge.Studies on the Neur-Endocrin-lmmunoregulatory Network (N-E-IN) and Its Regulation/Control Mechanism in Teleosts[J].Periodical of Ocean University of China,2006,36(1):60-64. |
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| Authors: | WEN Hai-Shen GAO Ling LI Wen-Ge |
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| Institution: | 1. College of Fisheries, Ocean University of China, Qingdao 266003, China; 2. Inner Mongolia University for Nationalities, Tongliao 028042, China |
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| Abstract: | The paper summarizes the advances in recent ten years on the neuro-endocrin-immunoregulatory network(N-E-IN) and its regulation/control mechanism in teleosts in terms of hypothalamus-pituitary-inerrenal(HPI) axis.The aspects involved in the immune function modulation are expounded.These are corticotrophin-releasing hormone(CRH),the polypeptide precursor,proopiomelanocortin(POMC),adrenocorticotropic hormone(ACTH),melanocytestimulating hormone(MSH),cortisol,growth hormone(GH),prolactin(PRL) and sexual steroid.The influence of environmental stress on the N-E-IN,and the effects of cytokines on the endocrine function are also elaborated.Future research directions in this field are presented. |
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| Keywords: | teleosts endocrine immune |
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