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Tissue enzymes as biomonitors of PCP intoxication in Notopterus notopterus
Authors:S. R. Verma  P. K. Tyagi  D. Dutt  R. Chand  A. K. Sharma
Abstract:In this paper, toxicity effects of pentachlorophenol have been studied using enzymes, phosphatases, transaminases and hydrogenases as indicators for toxicity. The sublethal concentrations used were 0.019, 0.0063 and 0.0038 mg/l (1/5th, 1/15th and 1/25th fractions of LC50) and the experimental fishes were exposed for the periods of 15, 30, 45 and 60 days. Most of the significant alterations in enzymes were observed at 1/5th and 1/10th fractions except at few places in the liver where a significant alteration in the enzyme acid phosphatase occurs at 1/15th fraction. Glutamic pyruvic transaminase (GPT) and glutamic oxaloacetic transaminase (GOT) and lactic dehydrogenase (LDH) showed a significant increase in different tissues in all the fractions of treatment.
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