Hyperglycemic response of Heteropneustes fossilis exposed to nickel

Freshwater Indian catfish H. fossilis was exposed to a sublethal concentration of 192 mg/1 nickel sulphate from 3 to 96 h. Blood glucose of the nickel exposed fish increased significantly at 6, 12, 24, 72 and 96 h. The maximum elevation was recorded at 72 h (P < 0.001). The possible role of glucagon and insulin has been discussed.