| 方格星虫多糖对小鼠免疫活性的影响 |
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| 引用本文： | 彭晓娜,雷晓凌.方格星虫多糖对小鼠免疫活性的影响[J].广东海洋大学学报,2007,27(4):54-57. |
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| 作者姓名： | 彭晓娜 雷晓凌 |
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| 作者单位： | 广东海洋大学食品科技学院,广东,湛江,524025 |
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| 摘 要： | 研究了方格星虫多糖对小鼠免疫功能的影响。结果表明:方格星虫粗多糖(CSG)能够对抗环磷酰胺引起的小鼠胸腺萎缩和脾萎缩,明显拮抗白细胞减少,对正常小鼠免疫器官没有明显的增重作用;对正常小鼠腹腔巨噬细胞吞噬中性红能力有显著的增强作用。方格星虫多糖粗品(CSG)和精制多糖(SG1和SG2)能够促进小鼠脾淋巴细胞增殖,且能与ConA协同作用。
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| 关 键 词： | 方格星虫 多糖 脾指数 胸腺指数 脾细胞 腹腔巨噬细胞 |
| 文章编号： | 1673-9159（2007）04-0054-04 |
| 修稿时间： | 2007-03-16 |
Effect of Polysaccharide Extracted from Sipunculus nudus on the Immunity of Mouse |
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| PENG Xiao-na,LEI Xiao-ling.Effect of Polysaccharide Extracted from Sipunculus nudus on the Immunity of Mouse[J].Journal of Zhanjiang Ocean University,2007,27(4):54-57. |
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| Authors: | PENG Xiao-na LEI Xiao-ling |
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| Institution: | College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524025,China |
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| Abstract: | The effect of polysaccharide extracted from Sipunculus nudus L. on immunity of mouse was studied. The results showed that crude polysaccharide extracted from S. nudus could antagonize the decrease of spleen and thymus weight caused by cyclophosphamide, but no remarkable effect on the normal mouse, and could obviously protect against leukocytopenia; crude and purified polysaccharide could enhance the proliferation of splenocyte, and had significant phagocytic function of peritoneal macrophages especially when cooperating with ConA. |
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| Keywords: | Sipunculus nudus L polysaccharide thymus index spleen index splenocyte peritoneal macrophage |
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