正常胰腺64层螺旋CT灌注成像的特征研究

应用多层螺旋CT对正常胰腺的CT灌注特点进行分析,研究正常胰腺灌注参数与年龄、性别的关系及正常胰腺不同部位灌注参数变化特征。30例胰腺正常者行腹部CT检查,其中3例健康志愿者,27例因其他疾病行腹部CT检查病人。按年龄分为3组:年龄小于40岁组、41岁~60岁组、大于61岁组。采用德国Siemens somatom Sensation64层螺旋CT进行胰腺动态增强扫描,层厚2.4mm,管电压100kV,管电流120mA。对比剂欧乃派克(300mgI/mL)100mL,Irich missouri高压自动注射器自动注射,注射速率为5mL/s,总量50mL。延迟6s开始扫描,共扫描30s。利用Siemens somatom Sensation型64层螺旋CT自带软件PCT进行处理得到灌注参数:F_b(血流量)、V_b(血容量)、T_tp(峰值时间)、P_S(表面通透性)等。正常胰腺血流灌注平均F_b、V_b、T_tp、P_S分别为(133.55±25.70)(mL/100mL/min)、(193.78±27.01)(mL/L)、(142.41±13.95)(0.1s)、(128.72±34.53)(0.5mL/100mL/min),不同年龄组间胰腺各灌注参数差异均无统计学意义(P>0.05)。男性平均F_b、V_b、T_tp、P_S分别为(127.59±22.90)(mL/100mL/min)、(188.72±25.19)(mL/L)、(142.91±13.17)(0.1s)、(133.30±42.86)(0.5mL/100mL/min)。女性平均F_b、V_b、T_tp、P_S分别为(142.48±28.04)(mL/100mL/min)、(201.37±28.94)(mL/L)、(141.66±15.63)(0.1s)、(121.85±14.80)(0.5mL/100mL/min)。两组间比较各灌注参数差异均无统计学意义(P>0.05),胰头、胰体、胰尾血流灌注平均F_b、V_b、T_tp、P_S差异均无统计学意义(P>0.05)。结果表明,螺旋CT灌注成像技术能有效检测胰腺血流灌注,正常胰腺灌注随年龄增长有下降趋势但无统计学意义。正常胰腺灌注与年龄、性别无关,胰腺各部位灌注均匀。

The Study to the Multisection Dynamic CT Perfusion on Normal Pancreas

To quantitative analysis and assess the blood perfusion characteristic of normal pancreas by Multisection dynamic CT.To investigate the perfusion parameters's change according to age, sex and difference locations of normal pancreas.30 cases with normal pancreas were examined for pancreatic perfusion and was divided into three sub-group according to age.The multisection dynamic CT perfusion series was performed for pancreatic perfusion on a multisection CT scanner(Siemens somatom Sensation 64), 120 kV, 100 m...