| 一种基于氨基酸物理化学性质上的DNA序列图形表示及相似性分析 |
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| 引用本文： | 刘法利,赵熙强.一种基于氨基酸物理化学性质上的DNA序列图形表示及相似性分析[J].中国海洋大学学报(自然科学版),2008,38(5). |
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| 作者姓名： | 刘法利 赵熙强 |
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| 作者单位： | 中国海洋大学数学系,山东,青岛,266071 |
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| 摘 要： | 基于氨基酸的物理化学性质,将氨基酸分为4类,疏水,带电荷,有极性,甘氨酸,在此基础上给出DNA序列一种新的图形表示方法:将1列DNA序列表示为二维空间中的3条特征曲线,利用计算C(i,j)矩阵的主特征值,给出DNA序列的3维特征向量,得到相似距离矩阵.最后计算10种不同物种β-球蛋白第一段外显子的欧式空间距离矩阵D(i,j),并利用UPGMA算法给出了这10种不同物种基于这种相似关系的系统发生树.
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| 关 键 词： | DNA序列 图形表示 氨基酸 相似性分析 进化树 |
A Novel Graphical Representation and Analysis of DNA Based on Physico-Chemical Properties of Amino Acids |
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| LIU Fa-Li,ZHAO Xi-Qiang.A Novel Graphical Representation and Analysis of DNA Based on Physico-Chemical Properties of Amino Acids[J].Periodical of Ocean University of China,2008,38(5). |
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| Authors: | LIU Fa-Li ZHAO Xi-Qiang |
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| Institution: | LIU Fa-Li,ZHAO Xi-Qiang(Department of Mathematics,Ocean University of China,Qingdao 266071,China) |
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| Abstract: | We considered a novel graphical representation of DNA sequences based on the physico-chemical properties of amino acids.For DNA sequences,using the classification of genetic codes and physico-chemical properties of amino acids,we constructed three curves of DNA sequences.The leading eigenvalues and normalized leading eigenvalues from the C(i,j) matrix were selected as invariants to characterize the degree of similarity between the DNA sequences.Construction of similarity/dissimilarity distance matrices base... |
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| Keywords: | DNA sequences graphical representation amino acids similarity or dissimilarity phylogenetic tree |
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