河南省肺癌空间分布格局及环境因素影响

肺癌是最常见的恶性肿瘤之一,也是主要的肿瘤死因,河南省肺癌发病率和死亡率常年居恶性肿瘤首位,研究肺癌的空间分布格局及其与环境因子的关系对肺癌的相关防控工作意义重大。本文以2016—2018年河南省肺癌发病数据为研究对象,使用空间自相关分析方法研究河南省肺癌的空间分布格局,基于地理探测器量化各个环境因子及其两两交互作用对肺癌发病率的解释力。结果表明：空间上肺癌具有明显的集聚特征,高发区集中分布于豫中、豫东和豫南的平原和盆地地区。在所选的12种环境因子中,PM_2.5浓度、O₃浓度、年均风速、采矿业从业人员占比、人均GDP具有更高的决定力,人均GDP和医护人员占比则对多种要素的决定力均具有明显的非线性增强的作用。研究结果可以为河南省肺癌发病机理研究和相关防治工作提供科学支撑。

Spatial distribution pattern and environmental impact of lung cancer in Henan

Lung cancer is one of the most common malignant tumors and the main cause of death related with cancer. The incidence rate and mortality rate of lung cancer in Henan are the highest of the cancers. Therefore, it is of great significance to study the spatial distribution pattern of lung cancer and the effects of environmental factors on it for the prevention and control of lung cancer. Based on the data of lung cancer incidence in Henan from 2016 to 2018, the spatial distribution pattern of lung cancer in the province was studied by using spatial autocorrelation analysis. Using the software Geodetector, we quantified the explanatory power of each factor and its interactions on lung cancer incidence rate. The results showed that lung cancer has obvious characteristics of agglomeration, the high incidence areas are concentrated in the plains and basins of central, eastern and southern Henan. Among the 12 environmental factors selected, PM_2.5 concentration, O₃ concentration, annual average wind speed, proportion of employees in mining industry and per capita GDP have decisive power, while the per capita GDP and proportion of medical staff have a non-linear enhancement effect on the determination of various factors. The results can provide technical support for research on pathogenesis, prevention and treatment of lung cancer in Henan.