磁共振成像早期诊断激素诱导股骨头缺血性坏死

目的探讨激素诱导股骨头缺血性坏死早期磁共振成像特征,和激素应用剂量,时间长短与股骨头缺血性坏死之间关系。材料和方法对108例患者有短期大量激素应用史患者行双髋关节平片及磁共振成像检查,分析图像特征,并应用统计学方法评价股骨头坏死与激素的关系。结果108例平片检查均为阴性,磁共振成像出现异常征象者35例,激素总量,日最大剂量及应用时间与股骨头坏死有统计学意义。结论:磁共振成像可以早期诊断激素诱导股骨头缺血性坏死,影像上单线征和双线征具有特异性;激素可以导致股骨头缺血性坏死。

Early Diagnose Corticosteroids-Induced Avascular Necrosis of Femoral Head by MRI

Objective:To evaluate the MRI sign of early corticosteroids-induced avascular necrosis of femoral head and the relationship between avascular necrosis of femoral head and total dosage,maximal daily dosage,course of using corticosteroids.Materials and methods:108 cases with heavy corticosteroids in a short period were enrolled,all examined with plain film and MRI.Analyze obtained image characteristics and the relationship between corticosteroids and avascular necrosis with statistical method.Results:Among the 108 cases,35cases show MRI abnormalities and all negative with plain films.There are statistical significance between avascular necrosis of femoral head and total dosage,maximal daily dosage,course of using corticosteroids.Conclusion:MRI can diagnose early avascular necrosis of femoral head,the single and double line sign have specificity.Corticosteroids can induce avascular necrosis of femoral head.