| 脑靶向紫杉醇纳米胶束的体外实验研究 |
| |
| 引用本文： | 陆恒,王雅杰. 脑靶向紫杉醇纳米胶束的体外实验研究[J]. 寒旱区科学, 2017, 9(5): 55-59 |
| |
| 作者姓名： | 陆恒 王雅杰 |
| |
| 作者单位： | 200433 上海, 第二军医大学附属长海医院;200433 上海, 第二军医大学附属长海医院 |
| |
| 基金项目： | 上海市自然科学基金资助项目（13NM1401504） |
| |
| 摘 要： | 目的 研发一种新型的治疗乳腺癌脑转移的靶向递药系统。方法 采用薄膜水化法制备载药胶束，将胶束与脑靶向分子Angiopep-2连接，使胶束具有脑靶向功能。结果 体外细胞实验证实该胶束具有良好的靶向性。结论 连接有靶向分子Angiopep-2的纳米胶束具有良好的脑靶向功能。
|
| 关 键 词： | 乳腺癌 脑转移 纳米 靶向 胶束 |
| 收稿时间： | 2016-11-21 |
| 修稿时间： | 2016-11-29 |
Brain Targeting Drug Nano Micelle in Vitro Experimental Study. |
| |
| Lu Heng and Wang Yajie. Brain Targeting Drug Nano Micelle in Vitro Experimental Study.[J]. Sciences in Cold and Arid Regions, 2017, 9(5): 55-59 |
| |
| Authors: | Lu Heng and Wang Yajie |
| |
| Affiliation: | Changhai Hospital, Second Military Medical University, Shanghai 200433, China;Changhai Hospital, Second Military Medical University, Shanghai 200433, China |
| |
| Abstract: | Objective To develop a novel targeted delivery system for the treatment of brain metastases from breast cancer. Methods Micelles were prepared by membrane hydration method, and the micelles were connected to Angiopep-2. Results The mi |
| |
| Keywords: | Breast cancer Brain Metastases Nano Targeting Micelles |
|
| 点击此处可从《寒旱区科学》浏览原始摘要信息 |
|
点击此处可从《寒旱区科学》下载全文 |
