Effects of Scotian shelf natural gas condensate on the mummichog |
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| Institution: | 1. Stem Cell Glycobiology Group, Division of Cancer & Stem Cells, School of Medicine, University of Nottingham, UK;2. Manchester Cancer Research Centre, Division of Molecular & Clinical Cancer Sciences, University of Manchester, UK;3. Laboratory of Biophysics and Surface Analysis, School of Pharmacy, University of Nottingham, UK;4. Stem Cell and Neurotherapies Group, University of Manchester, UK;5. Office of Business Relations, Faculty of Biology, Medicine and Health, University of Manchester, UK;6. Division of Cancer & Stem Cells, School of Medicine, University of Nottingham, UK;7. Division of Biomedical Engineering, School of Engineering, University of Glasgow, UK;8. Optics and Photonics Research Group, Faculty of Engineering, University of Nottingham, UK;9. SGC, Botnar Research Centre, NDORMS, University of Oxford, UK |
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| Abstract: | The 96h LC50 of the water soluble fraction (WSF) of natural gas condensate from the Sable Is., N.S. area to Fundulus heteroclitus was between 4 and 5 μg · ml?1 naphthalene equivalents (initial concentration). Behavioural responses in the fish to sub-lethal concentrations of WSF were similar to those recorded for crude and fuel oils. Induction of the hepatic mixed function oxidase enzyme enthoxyresorufin O-de-ethylase (EROD) in sexually immature fish occurred at WSF concentrations below the LC50, but during the prespawning period no induction occurred. EROD activity in unexposed fish showed seasonal variation consistent with differences in its inducibility. |
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