对比剂注射方案优化联合低管电压在主动脉CTA中的探讨

目的：探讨对比剂注射方案优化联合低管电压在主动脉CT血管成像（CTA）中应用的可行性。方法：临床行主动脉CTA检查患者80例，根据对比剂碘浓度及管电压分为A、B两组（n=40），A组根据对比剂碘浓度及注射速率分A1组和A2组（n=20）。A1组，注射300 mgI/mL北陆碘海醇溶液、注射速率4 mL/s，管电压100 kV；A2组，注射300 mgI/mL北陆碘海醇溶液、注射速率3.5 m L/s，管电压100 k V。B组，注射350 mgI/mL北陆碘海醇溶液、注射速率3.5 m L/s、管电压120 k V。其他扫描参数，注射对比剂容量，重建方式，自动管电流调节技术一致。采用两独立样本t检验（非正态分布采用Mann-Whitney U检验）来比较两组的临床资料、CT的辐射剂量、主观及客观评价图像质量等指标。结果：A组与B组比较，在年龄、性别、体质量指数（BMI）均无统计学差异（P>0.05）；在图像质量上主观评价及客观评价亦无统计学意义（P>0.05），B组CNR优于A组均达到诊断要求，测量主动脉各段的CT值均>300 HU；A组与B组辐射剂量有显著统计学意义（P<0.05），A组比B组有效辐射剂量（ED）降低了17.73%；在对比剂碘含量上A组比B组减少了14.29%。结论：注射300 mgI/mL碘海醇溶液、注射速率3.5 m L/s联合低管电压（100 kV）在主动脉CTA检查中取得了满意的图像质量，为临床提供了精准诊断依据，不仅降低了辐射剂量，还降低了碘含量。

Research on the Contrast Medium's Best Injection Combined with Low Tube Voltage in Aortic CTA

Objective: To explore the feasibility of contrast medium's best injection combined with low tube voltage in aortic CTA.Methods: Divided 80 patients who will be done aortic CTA examination into A, B two groups(n=40) by different contrast medium concentrations and tube voltages, while group A is divided into group A1, group A2(n=20) by different contrast medium concentrations and injection rate.Group A1: Injecting 302 mg I/mL Iohexol as contract medium, injection rate 4 mL/s, tube voltages 100 kV;group A2: Injecting 300 mg I/mL Iohexol as contract medium, injection rate 3.5 mL/s, tube voltages 100 kV;group B: Injecting 350 mg I/mL Iohexol as contract medium, injection rate 3.5 mL/s, tube vantage 120 kV;Other scanning parameters: Injection contrast dose, reconstruction mode, automatic tube current regulation technologies are consistent.Two independent sample tests are used(Mann-Whitney U test for non-normal distribution) to compare the clinic data, radiation dose of CT, subjective and objective evaluation of image quality in the two groups.Results: There was no significant difference in age, gender, body mass index(BMI) between group A and group B(P>0.05);there was also no statistical significance in the subjective and objective evaluation of image quality(P>0.05).The CNR of group B was better than group A, which met the diagnostic requirements, the CT values of the aortic trunk and branches were all>300 HU.There was statistically significant differences between group A and group B in radiation dose and iodine content(P<0.01).Effective radiation dose(ED) of group A was 17.73%lower than that of group B, and iodine content was 14.29%lower.Conclusion: injection of 300 mgI/mL Iohexol solution and injection rate of 3.5 mL/s combined with low tube voltage(100 kV) obtained satisfactory image quality in aortic CTA examination, providing accurate diagnostic basis for clinical practice, which not only reduced the radiation dose, but also reduced the iodine content.