| 汞、铅对非洲鲫鱼肝线粒体功能影响的初步研究 |
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| 引用本文： | 刘克强. 汞、铅对非洲鲫鱼肝线粒体功能影响的初步研究[J]. 海洋科学, 1985, 9(4): 36-38 |
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| 作者姓名： | 刘克强 |
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| 作者单位： | 中国科学院海洋研究所 |
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| 摘 要： | 为了研究和探讨重金属毒物对海洋生物的致毒机理及其对生物体内各种生化过程的影响,继镉、铜对非洲鲫鱼肝线粒体功能影响的研究之后,本实验继续以非洲鲫鱼(Tilapia mossambica)为实验材料,采用氧电极法测定了氯化汞、硝酸铅对鱼肝线粒体(离体)呼吸控制率和氧化磷酸化效率的影响。
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THE EFFECT OF MERCURIC CHLORIDE AND LEAD NITRATE ON THE FUNCTION OF LIVER MITOCHONDRIA OF TILAPIA MOSSAMBICA |
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| Abstract: | Mercuric chloride and lead nitrate were used separately at different concentrations as toxic agent on the liver mitochondria of Tilapia mossambica in vitro. The degree of coupling of oxidative phosphorylation-respiratory control and ADP/0 ratios of the liver mitochondria were examined by oxygen electrode measurements. In cases where sodium succinate was used as substrate, owing to inhibition of 2.5 ppm mercuric chloride on liver mitochondria, RCR and ADP/O ratios decreased markedly. |
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