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Detection of mRNA sequences homologous to the human glutathione peroxidase and rat cytochrome P-450IVA1 genes in Mytilus edulis
Authors:Peter Goldfarb   J.Andy Spry   Deborah Dunn   David Livingstone   Alan Wiseman  G.Gordon Gibson
Abstract:In this study we have used cloned gene probes for human glutathione peroxidase (GPX), rat cytochrome P-450IVA1 and rat cytochrome P-450IIE1 to detect homologous sequences in RNA from the hepato-pancreas of Mytilus edulis. The presence of sequences hybridising to the GPX and P-450IVA1 probes, but not to the P-450IIE1 probe, confirms the ancient origin of the former genes and indicates that conserved-sequence DNA probes from higher organisms can be used to examine the structure and function of genes of environmental interest in marine organisms.
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