Effects of ionizing radiation on the survival of bacterial spores in artificial martian regolith |
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Authors: | Ralf Moeller Manfred Rohde Günther Reitz |
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Institution: | a German Aerospace Center, Institute of Aerospace Medicine, Radiation Biology Department, Linder Hoehe, D-51147 Cologne (Köln), Germany b Helmholtz Centre for Infection Research, Department of Microbial Pathogenesis, Inhoffenstraße 7, D-38124 Braunschweig, Germany |
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Abstract: | Bacterial spores of Bacillus subtilis were used as a model system to study the effects of ionizing radiation on the survivability of spores uncovered and covered with artificial martian regolith. Spore survival after X-ray exposure was mainly depending on the role of non-homologous end-joining (NHEJ) as the major DNA double-strand break repair pathway during germination, the involvement of major small, acid-soluble spore proteins (SASP) as DNA radioprotectants and the coverage by martian regolith, whereas spores covered with martian regolith were significantly more sensitive to X-rays than uncovered spores, which is mainly due to the interaction of X-rays with artificial martian regolith resulting in the formation of secondary electrons and reactive oxygen species. |
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Keywords: | Mars Regoliths Astrobiology Exobiology |
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