| Abstract: | There is a body of literature indicating that pre-exposure to low levels of metals may increase tolerance during subsequent exposure.1 We have previously demonstrated that exposure to cadmium at 100 to 500 μg/liter will retard the rate of fin regeneration in the killifish Fundulus heteroclitus.2 These experiments were designed to investigate the effects of pre-exposure to cadmium, using fin regeneration as the parameter of effect. The results indicate that pretreatment allows this species to regenerate faster during cadmium treatment as compared to non-pretreated fish, and that the relationship between the pretreatment and treatment concentrations is relevant to pretreatment effects. |
