Coal mine workers' pneumoconiosis |
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Authors: | H-M Schulz H W Hagemann M Wolf A Brammertz H-J Einbrodt |
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Institution: | (1) Baltic Sea Research Institute, Department of Marine Geology, Seestrasse 15, 18119 Rostock, Germany, DE;(2) Department of Geology, Geochemistry and Deposits of Petroleum and Coal, Aachen University of Technology, Lochnerstrasse 4–20, 52056 Aachen, Germany, DE;(3) Department of Hygiene and Environmental Medicine, Aachen University of Technology, Pauwelsstrasse, 52074 Aachen, Germany, DE |
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Abstract: | The fibrogenic and cytotoxic potential of coal mine dust is independent of the amount of quartz and other inorganic parameters.
Results of coal petrographical and organic geochemical investigations of coals and coal mine dust from the Ruhr and Ibbenbüren
Region of Germany demonstrate variations of organic dust amount possibly influencing these noxious properties. Coal mine dust
of high rank coals is characterized by a pronounced fibrogenic risk. This risk, independent of the quantity of quartz, is
probably based on shape variations of different coal macerals. With increasing coalification of the corresponding seam, the
vitrinite is enriched in its dust; however, lower concentrations have been determined for inertinite. Vitrinite shows constant
shapes and sizes independent of the rank of coal. Inertinite particles with elongated to fibrous shapes tend to larger sizes
with increasing coalification. Strikingly, coal mine dust from miners' lungs with high degrees of coal mine workers' pneumoconiosis
(CWP) is enriched in inertinite. In contrast, high cytotoxicities in cell tests are known for coal mine dust from low coalified
coals. High concentrations of phenolic compounds can be extracted by dichloromethane from low coalified coal mine dust. These
compounds, which are characterized by a high water solubility and therefore high bioavailability, explain the high cytotoxicities
of coal mine dust. Contamination of dust by diesel emissions in the coal mine can act as additionally supporting parameters
for extended cytotoxicities.
Received: 18 August 1995 · Accepted: 15 October 1995 |
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Keywords: | Coal mine workers' pneumoconiosis Coalification Macerals Organic compounds Phenols |
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