人发中微量元素的原子光谱法测定及癌症病人初级临床诊断方法的研究

收集了厦门地区１３８例非癌症患者发样及６４例癌症病人发样。样品经湿法消化后，用电感耦合等离子体原子发射光谱（ＩＣＰ－ＡＥＳ）法测定其中２２种元素含量，用石墨炉原子吸收光谱（ＧＦ－ＡＡＳ）法测定了Ｓｅ含量，确定了厦门地区不同年龄段，不同性别发样中多种微量元素的含量范围。实验中通过对采样部位，采样方式，样品预处理方法（包括洗涤方法）、消化温度的比较及研究，选择了最佳实验条件，对发样中元素含量的纵向分布

Atomic Spectrometric Determination of Trace Elements in Hair Samples and Study on Preliminary Clinical Diagnostic for Cancer Patients

air samples were collected from Xiamen area which include 138 cases of normal people and 64 cases of cancer patients.The samples were analyzed for 22 elements by ICP-AES and for Seby GFAAS after a wet digestion. Background value of trace elements in the sarnples for differentages and sexes in Xiamen area were obtained.Experimental conditions were optimized,includingthe sampling position,the sampling method,the pretreatment methods and the digestion temperature of the samples.Concentration distribution along the growing length was also discussed.The results were treated with of PCA and PLS methods in order to distinguish cancer patientsand normal people. A preliminary clinical diagnostic model was established with a validity of92.3%.