运输系统的区域效应研究

运输系统改进—运距缩短—产业布局调整这一空间过程对不同的区域可能具有完全不同的意义。本文通过对一个两区域—两部门经济模型的研究得出结论:当较落后的资源产区与经济中心之间的距离由于运输系统的改进而缩短时,资源产区的经济结构向单一化转变,初级产品的生产和输出在经济建设中逐渐占主导地位,加工工业逐渐萎缩,地方经济发展受到阻碍,而且这种变化是在距离的某一特定值处突然出现的,带有跃变的性质。这一研究结果表明,对区域运输系统的任何改进措施都应该慎而行之,以免造成与本来目标相悖的区域效应。     

基于AGA的SVM需水预测模型研究

需水预测是一个由城市人口、工业水平、社会经济水平共同作用的多因素、多层次的复杂非线性系统.其结果将直接影响受区域水资源承载力约束的产业结构、布局形态等决策.作为一种集中参数预报方法,支持向量机方法具有对未来样本的较好的泛化性能,对于这类资料缺乏、系统结构尚欠清晰的问题可以取得较好的模拟和预测结果.基于此,本文将支持向量机方法引入需水预测领域,建立了需水预测支持向量机模型.同时,本文将加速遗传算法和支持向量机方法耦合起来,构造了支持向量机模型参数的自适应优化算法.模型在珠海市的应用实例表明:与简单遗传算法比较,AGA的模型参数寻优效率更高;与BP神经网络模型相比,SVM模型较好地解决了小样本、经验性等问题,并取得了较高的预测精度.     

基于生物信息学探讨骨质疏松症与2型糖尿病的关系

目的：基于生物信息学探讨骨质疏松症与 2 型糖尿病的关系。方法：通过基因表达汇编（GEO）数据库检索骨质疏松症和2型糖尿病的相关数据集,并筛选骨质疏松症-2型糖尿病共同差异表达基因,将数据导入STRING数据库找寻关键基因,以一个单细胞测序数据集作为检验集验证关键基因细胞层面的表达水平,对筛选结果进行基因本体（GO）功能及京都基因与基因组百科全书（KEGG）通路富集分析,并对关键靶点、相关中药进行频数统计及功效分类。结果：骨质疏松症与 2 型糖尿病相关通路集中在 ErbB信号通路、丝活化蛋白激酶（MAPK）信号通路、神经营养素信号通路、NOD样受体信号通路。频数统计结果显示,与骨质疏松症-2型糖尿病关键基因相关的中药有51味,以功效分类,可分为清热解毒药、止痛药、祛风药、补虚药、止呕药。结论：骨质疏松症和2型糖尿病都是复杂的代谢性疾病,涉及众多基因表达网络和信号通路。尽管两种疾病存在复杂的基因网络背景,但是分析结果表明两种疾病之间仍存在高度重合的差异基因表达和信号通路。这表明两种疾病的分子机制密切相关,可能存在共同调控的靶点,因此这些靶点可能成为药物同时干预两种疾病的治疗靶点。     

南海北部主要经济鱼类体长与体重关系

文中根据1997～1999年和2001～2002年期间在南海北部底拖网调查的43种共33 389尾鱼的体长（叉长、肛长）和体重数据,应用统计分析方法对各鱼种体长与体重关系进行分析.结果表明,43种鱼分别隶属于4目16科25属,相关系数R^2的范围为0.764～0.993,相关系数R^2值相对较高,其中58%的R^2值超过0.95.幂指数b值范围为2.50～3.44,平均2.90.盒须图分析表明,50%的b值在2.79～3.01范围.经初步分析,43种主要经济鱼类中,有16种为等速生长、22种负的异速生长和5种正的异速生长.     

Study on copper complexing ligand concentrations in several China’s coastal waters

Copper complexing ligand concentrations in the Daya Bay, Qingdao coast, Jiaozhou Bay, South China Sea and Huanghe Estuary waters were determined by the anodic stripping voltammetry technique. The distribution regularity and the relationship with other parameters were discussed. The results were as follows: Copper complexing ligand concentrations of the South China Sea were a little higher than those of other sea areas, and they were apparently higher than those of the ocean. Compared with the subsurface layer (SSL) in the sea surface microlayer copper complexing ligand concentrations showed an enrichment phenomenon, of which the mechanism is similar to dissolved organic matter. The metal complexing ligand concentration profiles of the South China Sea showed that the value in the sea surface was the highest, then it decreased with depth accruing, and a higher value appeared at the bottom. Copper complexing ligand concentrations were higher than those of cadmium and lead. Ligands in each sea area exhibited a complicated property. In short, the distribution regularity of copper complexing ligand concentrations in China' s coastal waters was consistent with that of other regions in the world. Meanwhile, the positive relationship between the copper complexing ligand concentrations and biological oxygen demand, chemical oxygen demand, dissolved organic carbon, and viscosity were found clearly.     

完全混合活性污泥法处理含海水污水时基质降解与需氧量之间的关系

文章采用完全混合活性污泥法研究了大生活用海水进入城市污水系统后 ,不同海水盐度下基质降解与需氧量之间的关系。结果表明随着污水中海水比例的增加 ,代谢单位重量有机物所需的氧量和污泥自身氧化需氧率也呈增加趋势     

Application of Microbial BOD Sensors in Marine Monitoring

A strain of yeast, which can endure high osmotic pressure, is employed for the sensitive material of the microbial BOD sensor. Two immobilization methods are used, I.e. Calcium alginate gel be ads and PV A gel beads. The results show that the PVA gel beads is better. The influences of osmosis and heavy metal ions on the yeast entrapped in the PVA gel beads are also studied in the experiment.