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白细胞介素17受体(Interleukin 17 receptor,IL-17R)家族与IL-17细胞因子家族介导的各类反应有着密切联系.IL-17RE-like(IL-17REL)是一类最新发现的IL-17受体,其结构与IL-17RE相似,但尚未发现其配体.本研究克隆得到大黄鱼(Larimichthys crocea)IL-17REL(Lyc IL-17REL)的全长c DNA,其开放阅读框全长1 659个核苷酸,推断可编码一个由552个氨基酸组成的蛋白,含有信号肽、胞外段、跨膜区和胞内段.与其他物种的IL-17REL相似,Lyc IL-17REL蛋白的胞外段具有一个保守的FN I-like结构域,而胞内段缺少IL-17受体家族保守的SEFIR(SEF and IL-17R)结构域.多序列比对分析表明Lyc IL-17REL与日本河豚(Takifugu rubripes)IL-17REL的氨基酸序列同源性最高,序列一致性可达57.0%.系统进化分析表明,脊椎动物的IL-17受体家族可分为2类,IL-17RA/RB/RD为一类,IL-17RC/RE/REL为一类.其中鱼类及高等脊椎动物的IL-17REL与IL-17RE亲缘关系最近,并且推测二者可能是由同一基因从硬骨鱼类之前的物种中分化而来.组织分布表明Lyc IL-17REL在所有被检测的组织中为组成型表达,在黏膜相关组织如小肠和鳃中的表达量最高.大黄鱼受嗜水气单胞菌(Aeromonas hydrophila)诱导刺激后,Lyc IL-17REL在其头肾及鳃中的基因转录水平均显著上调.这表明Lyc IL-17REL可能在细菌感染引起的免疫反应中起着重要作用.  相似文献   
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We present results of CCD photometric observations of the short-period W UMatype contact binary system, RZ Com. The light curve of the binary has changed from Wsubtype to A-subtype from 1998 to 2003, then back to W-subtype in 2004. An analysis was carried out using the 2003 version of the Wilson-Devinney code. It is confirmed that RZ Com is a low-degree, overcontact f = 20.1% (±7.4%) binary system with a high inclination of i = 81.°40 (±0.°40), and a mass ratio q = 2.351 (±0.031). Combining four newly determined times of light minimum with others in the literature, the variations in orbital period is examined. A small-amplitude oscillation (A=0.0065d), with a period of 41.5 year, is discovered superimposed on a long-term increase at rate dP/dt = +3.97×10-8d yr-1. The period oscillation can be explained either by the light-time effect due to the presence of an unseen third body, or by cycles of magnetic activity on the components. Combining our photometric solution with the spectroscopic elements obtained by Mclean & Hilditch, the absolute dimensions of RZ Com are: M1 = 1.14 (+0.19)Mo, M2 = 0.50 (-4-0.09)Mo, R1= 1.12 (±0.01)R⊙, R2 = 0.78 (±0.01)R⊙ and A = 2.41 (±0.02)R⊙.  相似文献   
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We present and analyze long‐term optical photometric measurements of the three active stars V2253 Oph, IT Com and IS Vir. All three systems are single‐lined spectroscopic binaries with an early K giant as primary component but in different stages of orbital‐rotational synchronization. Our photometry is supplemented by 2MASS and WISE near‐IR and mid‐IR magnitudes and then used to obtain more accurate effective temperatures and extinctions. For V2253 Oph and IT Com, we found their spectral energy distributions consistent with pure photospheric emission. For IS Vir, we detect a marginal mid‐IR excess which hints towards a dust disk. The orbital and rotational planes of IT Com appear tobe coplanar, contrary to previous findings in the literature. We apply a multiple frequency analysis technique to determine photometric periods, and possibly changes of periods, ranging from days to decades. New rotational periods of 21.55±0.03 d, 65.1±0.3 d, and 23.50±0.04 d were determined for V2253 Oph, IT Com, and IS Vir, respectively. Splitting of these periods led to tentative detections of differential surface rotations of δP/P ≈ 0.02 for V2253 Oph and 0.07 for IT Com. Using a time‐frequency technique based on short‐term Fourier transforms we present evidence of cyclic light variations of length ≈ 10 yr for V2253 Oph and 5–6 yr for IS Vir. A single flip‐flop event has been observed for IT Com of duration 2–3 yr. Its exchange of the dominant active longitude had happened close to a time of periastron passage, suggesting some response of the magnetic activity from the orbital dynamics. The 21.55‐d rotational modulation of V2253 Oph showed phase coherence also with the orbital period, which is 15 times longer than the rotational period, thus also indicating a tidal feedback with the stellar magnetic activity. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)  相似文献   
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UBVRI photometric observations and models of spotting are presented for four noneclipsing RS CVn systems: IN Com (G5III/IV), IL Com (F8V+F8V), UX Ari (K01V+G5V), and V711 Tau (K1IV+G5V). A low amplitude variability caused by cold (T=1700K)spots which can occupy up to 19% of the star's surface is confirmed for the little-studied star IL Com. Long-term light curves are constructed and the stellar magnitudes and color indices of the unspotted photospheres are estimated for IN com, UX Ari, and V711 Tau. It is shown that UX Ari becomes bluer with decreasing brightness, so its variability cannot be fully explained in terms of cold spots. Models of spotting on In Com and V711 Tau are constructed from the full set of available photometric observations. The spots on both of these variables lie at middle latitudes and occupy up to 22% (In Com) and 33% (V711 Tau) of the stars' surfaces. Both stars manifest a tendency for the width of the spots to decrease as their area increases. This is a crude analog of the Maunder butterflies. These stars experience cyclical spot activity and have a differential rotation of the type found on the sun.  相似文献   
7.
针对宅基地管理的具体需求,在.NET框架的Visual Studio集成开发环境中,以Visual C#为开发语言,利用ArcGIS Engine组件开发了与用户交互的宅基地管理系统。该系统以大型关系数据库Oracle为核心,采用空间数据库引擎ArcSDE实现空间数据在关系数据库中的存储和管理,实现了地图浏览、宗地信息查询、规划分析等功能。系统的建立有利于促进宅基地管理工作的科学化和规范化,并且实现了城乡规划许可证审批功能,大大地提高了工作效率和管理水平,对基层国土部门的国土资源信息化建设具有实际意义。  相似文献   
8.
We present the frequency analysis of the multicolour time series photometry of the field RRd variable BS Comae. The large number of data points in each of the BV (RI)C bands and the ∼0.01 magnitude accuracy of the individual measurements allow us a high precision analysis of the properties of the combination frequencies due to nonlinear coupling. Through the combination of the frequency spectra in different colors we show that except for the components corresponding to the linear combinations of the two pulsation modes, there are no other components present above the millimagnitude amplitude level. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)  相似文献   
9.
Due to the unique chemical properties and therefore wide range of applications, significant amounts of reactive dyes often end up in waste waters and this issue raises the need for more efficient treatment technologies. This work investigates the ability of magnetite nanoparticles functionalized with imidazolium based ionic liquid (IL) as an efficient sorbent for the removal of the Reactive black 5 from wastewater. Fourier transform infrared spectroscopy, X‐ray diffraction, transmission electron microscopy, thermo‐gravimetric analysis, and zeta potential measurement were used to characterize the synthesized nanosorbent. The results showed that under optimal conditions, the dye removal efficiency of the grafted IL is 98.5% after a single run. Regeneration of the used sorbent could be possible and the modified magnetic nanoparticles exhibited good reusability. The isothermal data of RB5 sorption conformed well to the Langmuir model and the maximum sorption capacity of IL@Fe3O4 for RB5 was 161.29 mg g?1. Thermodynamic study indicated that the adsorption is endothermic and spontaneous. The use of such a system can provide fast and efficient removal of the reactive dyes from wastewater by using an external magnetic field.  相似文献   
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