紫阳滑坡治理工程实例分析

本文介绍紫阳骨坡治理工程中有关抗滑桩的设计与施工。文中详细地论述了设计中设计人员应根据工程的具体情况去灵活处理的一些技术问题，如确定有关参数的选择原则，计算上的条件简化和一些具体技术细节的处理方法等．     

天文(重力)水准的新手段及其计算方法

介绍当今确定天文大地垂偏差的新仪器－CCD自动天体测量仪和确定两点间高程异常差的新方法，该方法用单极坐标代替繁琐的双极坐标进行计算，讨论了天文重力水准的误差及垂线偏差非线性影响等问题，估计在不久的将来，用这一手段施测山区似大地水准面的精度可望达到厘米级。     

基于Poulos弹性理论的被动桩改进算法

传统的Poulos弹性理论仅适合于均质土中土体侧向位移时桩的性状分析,无法考虑土的层状特性。通过引入层状地基中作用一水平集中力的广义Mindlin解和地面作用有竖向荷载时的应力和位移通解,对Poulos方法进行了改进,使之扩展到多层土中,还用于研究堆载条件下的被动桩变形和受力响应。算例分析表明,改进弹性理论要比Poulos方法更为严密、合理,提高了计算精度,应用范围也更广。     

基于生物信息学探讨骨质疏松症与2型糖尿病的关系

目的：基于生物信息学探讨骨质疏松症与 2 型糖尿病的关系。方法：通过基因表达汇编（GEO）数据库检索骨质疏松症和2型糖尿病的相关数据集,并筛选骨质疏松症-2型糖尿病共同差异表达基因,将数据导入STRING数据库找寻关键基因,以一个单细胞测序数据集作为检验集验证关键基因细胞层面的表达水平,对筛选结果进行基因本体（GO）功能及京都基因与基因组百科全书（KEGG）通路富集分析,并对关键靶点、相关中药进行频数统计及功效分类。结果：骨质疏松症与 2 型糖尿病相关通路集中在 ErbB信号通路、丝活化蛋白激酶（MAPK）信号通路、神经营养素信号通路、NOD样受体信号通路。频数统计结果显示,与骨质疏松症-2型糖尿病关键基因相关的中药有51味,以功效分类,可分为清热解毒药、止痛药、祛风药、补虚药、止呕药。结论：骨质疏松症和2型糖尿病都是复杂的代谢性疾病,涉及众多基因表达网络和信号通路。尽管两种疾病存在复杂的基因网络背景,但是分析结果表明两种疾病之间仍存在高度重合的差异基因表达和信号通路。这表明两种疾病的分子机制密切相关,可能存在共同调控的靶点,因此这些靶点可能成为药物同时干预两种疾病的治疗靶点。     

Efficiency analysis of open trench for impact pile driving through a single-variable method

Abstract

The ground vibrations during pile driving operation have a drastic potential to undermine the surrounding structures both in land and reclaimed land. Particularly, reclaimed land necessitates ample application of pile driving due to the weak land condition. To prevent the structural damage, attenuation of the ground vibrations to an allowable level through active isolation of circular open trench is the scope of this study. In this research, finite element simulations of continuous impact pile driving process from the ground surface was executed with particular attention to the pile-soil interaction, and thereby, the efficiency of open trench application in attenuation of the unsafe distance of different structures was surveyed using the vibration sensitivity degree. Regarding the crucial parameters of an open trench (depth, width, and location), it was concluded that a sufficient high depth can attenuate the unsafe distance up to 68%, the trench width variations are less effective, and an average pile-trench distance is the most efficient option. The excavation volume was also concluded as another crucial parameter in open trench design which takes all three parameters into account. The trench depth equal to the pile’s maximum critical depth of vibration was inferred for an optimum design.     

ISD单片语音录/放器件及电路设计

指出ＩＳＤ单片语言器件的独特之处，是采用直接模拟存储技术，语音信号以其原本的模拟形式直接存入模拟量存储器中并长远保存。省去了传统的Ａ／Ｄ和Ｄ／Ａ数模转换机制，能高保真的将语音内容再生。这是一种高新录／放技术。另外，给出的ＩＳＤ基本录／放电路十分简单易用。可方便地为微机系统、测控仪表电器和广播等设备所采用，使设备具有高效功能     

Wave-Current Forces on Vertical Cylinders in Side-by-Side Arrangement for Irregular Waves Combined With Opposing Current

- The wave-current forces on vertical piles in side-by-side arrangement induced by irregular waves with opposing current are investigated experimentally in this paper. The characteristics in both time and frequency domain of in-line, lift and resultant forces are analyzed. The grouping effect coefficients of inline, lift and resultant forces on piles related to KC number and relative spacing parameters are given. These results are compared with those in the case of irregular waves combined with following currents. It is found that the results in these two cases are quite different. The range of KC number tested is 10- 60, the range of Reynolds number is (0.55-3.43) ×104.     

An Approach to Stability Analysis of Embedded Large-Diameter Cylinder Quay

The large-diameter cylinder structure, which is made of large successive bottomless cylinders placed on foundation bed or partly driven into soil, is a recently developed retaining structure in China. It can be used in port, coastal and off-shore works. The method for stability analysis of the large-diameter cylinder structure, especially for stability analysis of the embedded large-diameter cylinder structure, is an important issue. In this paper, an idea is presented that is, em-bedded large-diameter cylinder quays can be divided into two types, i.e. the gravity wall type and the cylinder pile wall type. A method for stability analysis of the large-diameter cylinder quay of the cylinder pile wall type is developed and a method for stability analysis of the large-diameter cylinder quay of the gravity wall type is also proposed. The effect of sig-nificant parameters on the stability of the large-diameter cylinder quay of the cylinder pile wall type is investigated through numerical calculation.     

Behavior of Pile Groups under Lateral Load

Based on investigation and model tests, and in combination with the research work on group effect for pile groups under lateral loads relating to the code of fixed offshore platforms, a series of studies have been performed on the behavior and failure mechanism of laterally loaded pile groups, critical pile spacing inducing group effect, lateral bearing capacity of pile groups and its main influence factors, the stress-strain relationship for single piles and pile groups and so on. Some new laws about non-uniformity of load distribution in the longitudinal direction of pile groups and load-deflection (p - y) curves for pile groups have been discovered, and an empirical formula is presented in order to remedy the defect of current calculating methods at home and abroad. These results can be used for reference in the design of pile foundation under lateral loads.