Human spaceflight in the UK: the cost of non-participation

Human space exploration is not considered a strategic priority in the United Kingdom at present. However the UK would benefit from participating in human spaceflight, for both scientific and social reasons. From the point of view of medical science there are many parallels between the physiology of spaceflight and terrestrial disease processes, and studies of the response of astronauts to long-duration spaceflight can therefore help in the development of therapeutic strategies on Earth. On the social side, human spaceflight is an attractive vehicle for stimulating the interest of young people in science and engineering, something that must be of value for an aspiring ‘knowledge-based’ economy.     

Framing in geographical analysis of environmental conflicts: Theory, methodology and three case studies

When applied to environmental concerns, framing offers a rigorous conceptual and analytic approach with potentially practical significance for dealing with complex issues relevant to geography. The purpose of this article is to introduce framing concepts, typology and modes of analysis to address issues which geographers commonly treat: disputes over land ownership and uses, competition for water resources, cultural clashes over control of territory and resources and the impact of spatial patterns and structures when siting noxious sites. Framing analysis is applied to three cases of environmental conflict in Israel and, more generally, for understanding conflicts revolving around the management of human habitats in relation to the physical environment.     

二色桌片参酶解液对转化细胞的效应

用二色桌片参（Mensamariaintercedens）酶解液处理转化的人胚肺成纤维细胞（NLF）后，细胞生长受到显著抑制，抑制率达64．84％，光镜下细胞透光性加强，铺展较好，细胞核形更为规则，核畸形现象减少；线粒体结构趋于正常；软琼脂集落实验表明，细胞集落形成率由23ｘ10－5下降至12．5ｘ10－5，裸小鼠致瘤实验显示抑瘤率为82．39％，差异显著（p＜5％）。结果提示，二色桌片参酶解液可能逆转转化的HLF细胞的恶性表型，对其有一定的诱导分化作用。     

Results from a Multi-disciplinary Sedimentary Pilot Study of Tectonic Lake Iznik (NW Turkey) – Geochemistry and Paleolimnology of the Recent Past

A limnogeological reconnaissance study was carried out on Lake Iznik, located in the southeast of the Marmara region of Turkey, involving a seismic survey and collection of short sediment cores. This lake is located on the middle branch of the North Anatolian Fault Zone (NAFZ), a transform plate boundary between the Eurasian and Anatolian Plates. It is, therefore, tectonically active and offers an opportunity to investigate the interplay of sedimentary and seismo-tectonic processes, as well as climate change and human impact in the region. Short cores of the three sub-basins, maximum length of 35.5 cm, recovered non-laminated, blackish clays and silts with varying amounts of biogenic and minerogenic (allochthonous, autochthonous) material, which documented almost the last 80 years of deposition and environmental history. High sedimentation rates in the deeper core sections are accompanied by changes in land use (conversion of woodland to farmland) in the northern areas of Lake Iznik, which caused the deposition of more weathered material (high K/Na ratios) and higher contents of Mn in the lake. A tendency towards eutrophic conditions within the last 20 years is indicated by high nutrient content (N, TOC, P), decreasing C/N-ratios, and characteristic diatom and cladoceran associations. Also increased pollution is revealed by higher Pb, Cu, and Zn contents and increased supply of human and animal faeces (high coprostanol content) during the last two decades. But simultaneous lower sedimentation rates towards the core tops complicate the reconstruction of recent and past eutrophication and pollution states of Lake Iznik. This requires an extension of the pilot study and deeper sediment cores, to recover non-anthropogenic influenced sediment levels.     

Arsenic, antimony and other toxic elements in the drinking water of Eastern Thessaly in Greece and its possible effects on human health

Twenty-six groundwater samples were collected from the Eastern Thessaly region and analysed by ICP-ES for these elements: Al, As, P, Pb, Zn, Mn, Fe, Cr, Sb, Cu, Na, Br, Cl, Si, Mg, Ag, Be, Bi, Dy, Er, Eu, Au, Ge, Ho, In, Ir, Os, Pt, Re, Rh, Ru, Lu, Hf, Hg, Tm, Zr and Nb. The objectives of the study were to assess the level of water contamination with respect to the EC and the USEPA health-based drinking water criteria. The geology of the studied area includes schists, amphibolites, marbles of Palaeozoic age, ophiolites, limestones of Triassic and Cretaceous age, Neogene and Quaternary deposits. The element ranges for groundwater samples are: Al 7–56 μg l⁻¹, As 1–125 μg l⁻¹, Br 6–60 μg l⁻¹, Cl 500–25,000 μg l⁻¹, Cr 1–6 μg l⁻¹, Cu 1–15 μg l⁻¹, Fe 10–352 μg l⁻¹, Mg 2,940–40,100 μg l⁻¹, Mn 0–8 μg l⁻¹, Na 3,650–13,740 μg l⁻¹, P 20–48 μg l⁻¹, Pb 0–7 μg l⁻¹, Sb 0–21 μg l⁻¹, Si 3,310–13,240 μg l⁻¹ and Zn 7–994 μg l⁻¹. The results of groundwater analyses from the region of Eastern Thessaly showed elevated concentrations of As and Sb. Factor analysis explained 77.8% of the total variance of the data through five factors. Concentration of Br, Cl, Mg, Na and Si is directly related to the presence of saltwater in the aquifer, so grouping of these variables in factor 1 probably reflects the seawater intrusion. Al, As and Sb are known to form complexes in the environment, so grouping of these elements in factor 2 indicates their similar geochemical behaviour in the environment. The high negative loading of Mn in factor 2 indicates the presence of manganese oxides–hydroxides in the study area. Pb and Zn are associated together in sulphide mineralisation; so grouping of these elements in factor 3 reflects the sulphide mineralization paragenesis in the Melivoia area. P and Cu are associated together in phosphate fertilizers; so grouping of these variables in factor 4 could be related to agricultural practices. Cr, Fe, Mn and Mg are associated together in iron and manganese oxides–hydroxides and the weathering products of the olivine of the ultrabasic rocks; so grouping of these elements in factor 5 reflects the lithology of the area. There is a natural contamination of groundwaters with elevated concentrations of As and Sb due to the presence of the arsenopyrite and stibnite mineralisation in the Melivoia, Sotiritsa and Ano Polydendri areas. Contamination over the health-based drinking water guidelines given by EC and EPA has been investigated from nine sampling sites out of 26 of Eastern Thessaly region.     

Environmental and health risk assessment in abandoned mining area, Zlata Idka, Slovakia

The Zlata Idka village is a typical mountainous settlement. As a consequence of more than 500 years of mining activity, its environment has been extensively affected by pollution from potentially toxic elements. This paper presents the results of an environmental-geochemical and health research in the Zlata Idka village, Slovakia. Geochemical analysis indicates that arsenic (As) and antimony (Sb) are enriched in soils, groundwater, surface water and stream sediments. The average As and Sb contents are 892 mg/kg and 818 mg/kg in soils, 195 mg/kg and 249 mg/kg in stream sediments, 0.028 mg/l and 0.021 mg/l in groundwater and 0.024 mg/l and 0.034 mg/l in surface water. Arsenic and Sb concentrations exceed upper permissible limits in locally grown vegetables. Within the epidemiological research the As and Sb contents in human tissues and fluids have been observed (blood, urine, nails and hair) in approximately one third of the village’s population (120 respondents). The average As and Sb concentrations were 16.3 μg/l and 3.8 μg/l in blood, 15.8 μg/l and 18.8 μg/l in urine, 3,179 μg/kg and 1,140 μg/kg in nails and 379 μg/kg and 357 μg/kg in hair. These concentrations are comparatively much higher than the average population. Health risk calculations for the ingestion of soil, water, and vegetables indicates a very high carcinogenic risk (>1/1,000) for as content in soil and water. The hazard quotient [HQ=average daily dose (ADD)/reference dose (RfD)] calculation method indicates a HQ>1 for groundwater As and Sb concentrations.     

区域环境变迁与持续发展的互动关系

区域历史进程中持续发展与环境变迁表现出了复杂的互动关系，两种动态过程紧密地交织在一起，通过人类活动互相作用，互相影响，持续发展，环境变迁与人类活动的内容在不同时代表现出不同的主题，并受到自然和人为因素的调节与控制，文中还简要阐明了当代可持续发展的主题，指出解决PRED问题要注意控制人口数量，提高人口素质；消除贫困，达到全球环境共有共治共保共享。     

Natural environmental changes and human impact reflected in sediments of a high alpine lake in Switzerland

From the high alpine Sägistalsee (1935 m a.s.l.), 13.50 m of continuously laminated sediments comprising the last 9050 years, were analyzed. Even though Sägistalsee is a high elevation site, human-induced environmental changes start as early as 4300 cal. BP and leave a clearly detectable signal in the mineralogy of the sediments, which is much stronger than the signal from natural environmental changes that occurred before this time. Variations in the physical and mineralogical sediment properties of this clastic sequence reflect erosional changes in the catchment, where almost pure limestone contrasts with carbonaceous, quartz-bearing marl, and shist. The calcite/quartz (Cc/Qz) ratio was found to be most indicative of these changes, which occurred around AD 1850 and at 650, 2000, 3700, and 6400 cal. BP. The first four are interpreted as erosion events, which are related to human-induced changes in the vegetation cover and land use. We associate them to the recent development of tourism and grazing, the medieval intensification of pasturing, Roman forest clearance, and Bronze Age forest clearance, respectively. The Cc/Qz-ratio increases significantly within less than 100 years during these events, reflecting the erosion of unweathered or poorly weathered soils. The time intervals in between are characterized by a gradually decreasing Cc/Qz-ratio and reflect the stabilization or formation of new soils. Only the change at 6400 cal. BP, which represents the initial gradual stabilization of the catchment, is related to the immigration of Picea abies.     

晚更新世以来青海北部的人类活动与湖泊演变

作为高海拔生态环境的青海北部是青藏高原的重要组成部分。晚更新世晚期以来 ,青海北部气候环境一直处于冷暖、干湿波动过程之中 ,湖泊水域也发生了相应的扩张和收缩 ,成为高原人类迁移和发展的自然背景。约 3 0kaB .P .,在晚期智人出现和迁徙的关键时期 ,青海北部开始有了最早的人类活动 ;更新世末—全新世初 ,气候转暖 ,古人类再次来到青海北部 ;进入全新世中期 ,气候暖湿 ,湖水位回升 ,细石器技术变得十分普通 ,青海北部的人类活动渐趋频繁。