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1.
Collagen of squid(Ommastrephes bartrami) skin was examined in the present study. Histology showed that collagen fiber in the skin was partially cross-linked with muscle fiber. Acid-solubilized collagen(ASC) and pepsin-solubilized collagen(PSC) were extracted from the skin and characterized. The results of amino acid composition and electrophoretic patterns revealed that ASC and PSC were both type Ⅰ collagen,containing α1 and α2 chains. FTIR(fourier transform infrared spectroscopy) investigations confirmed t...  相似文献   
2.
Analysis of multivariate response data by modelling the principal components of the response has beenapplied to two sets of data. In both cases principal components analysis revealed the relationships amongthe response variables and exploited them to simplify the problem of modelling and optimizing themultivariate response. The models and optima obtained from the principal components comparedfavourably with the individual models and simultaneous optima.  相似文献   
3.
In this study,we evaluated the anti-proliferative activity of phlorotannins derived from brown algae Laminaria japonica Aresch extracts on the human hepatocellular carcinoma cell (BEL-7402) and on murine leukemic cells (P388) by MTT assay.Cells were incubated with 100 μg/mL of the phlorotannin extract (PE) for 48 h.The inhibitory rate of PE on BEL-7402 and P388 cells was 30.20±1.16% and 43.44±1.86%,respectively,and the half-inhibitory concentration of PE (IC50) on P388 and BEL-7402 cells was 120 μg/mL and >...  相似文献   
4.
A ROBUST PLS PROCEDURE   总被引:1,自引:0,他引:1  
A robust partial least squares(PLS)regression algorithm is developed.This is achieved by substitutionof the univariate regression steps in the iterative PLS2 algorithm by a robust alternative.The anglebetween loading vectors from both perturbed and unperturbed solutions is used as a measure ofrobustness.By means of a perturbation study on a structure-activity data set,it is demonstrated thatthe stability of the robust method is superior to standard PLS.  相似文献   
5.
When the number of variables exceeds the number of samples, one method of multivariate discriminationis to use principal components analysis to reduce the dimensionality and then to perform canonicalvariates analysis (PC-CVA). This paper proposes an alternative approach in which discriminant analysisis carried out by a weighted principal component analysis of the group means (DPCA). This method doesnot require prior data reduction and produces discriminant factors that are orthogonal in the original dataspace. The theory and performance of the two methods are compared. Although the individual factors ofDPCA are found to be less discriminating than PC-CVA, the overall discrimination, calculated bymultivariate analysis of variance, and the predictive value, estimated by the leaving-one-out error rate,are broadly comparable.  相似文献   
6.
城市环境地球化学研究综述   总被引:20,自引:0,他引:20  
近年来地球科学越来越多地面向城市,城市环境受到人类活动的广泛影响,自然及人类活动引起的城市地球化学问题日益受到人们的重视。城市环境地球化学是应用地球化学的原理和方法研究城市生态环境问题,主要研究城市土壤、沉积物、尘埃、地表水、地下水、生物、空气等介质中化学元素及同位素的分布、演化、环境作用及健康效应,重点解决城市地球化学环境质量变化的原理及由此产生的生态环境效应及人体健康效应。城市环境地球化学的主要研究对象是传统工业城市、典型矿业城市及国际化的大都市。在城市地球化学概念出现之后短短的10余年时间内,很多国家开展了城市环境地球化学调查和研究工作,取得了重要的成果和进展,并发展成为环境地球化学与城市环境的重要方向,但仍存在着一定的问题,需要深入研究。目前,城市环境系统的地球化学填图、城市地球化学与环境污染研究、城市地球化学与生态风险研究、城市地球化学与人体健康研究、城市地球化学系统的调控与环境规划等领域是国际城市环境地球化学的热点和前沿。  相似文献   
7.
A TEST OF SIGNIFICANCE FOR PARTIAL LEAST SQUARES REGRESSION   总被引:1,自引:0,他引:1  
Partial least squares (PLS) regression is a commonly used statistical technique for performingmultivariate calibration, especially in situations where there are more variables than samples. Choosingthe number of factors to include in a model is a decision that all users of PLS must make, but iscomplicated by the large number of empirical tests available. In most instances predictive ability is themost desired property of a PLS model and so interest has centred on making this choice based on aninternal validation process. A popular approach is the calculation of a cross-validated r~2 to gauge howmuch variance in the dependent variable can be explained from leave-one-out predictions. Using MonteCarlo simulations for different sizes of data set, the influence of chance effects on the cross-validationprocess is investigated. The results are presented as tables of critical values which are compared againstthe values of cross-validated r~2 obtained from the user's own data set. This gives a formal test forpredictive ability of a PLS model with a given number of dimensions.  相似文献   
8.
Coccolithophorid is unicellular marine microalgae with a global distribution in temperate and sub-temperate oceanic regions and has the ability to produce ‘the coccoliths'. It is considered to be the second most productive calcifying organism on earth and becoming an important factor in the global carbonate cycle. Emiliania huxleyi is one of the only two bloom-forming coccolithophores and becomes a species crucial to the study of global biogeochemical cycles and climate modeling. Coccolithoviruse is a recently discovered group of viruses infecting the marine coccolithophorid E. huxleyi. They are a major cause of coccolithophore bloom termination, and DMSP concentration is increasing in the process of viral lysis. Phylogenetic evidences support that some genes are functional both in E. huxleyi and its virus(Eh V). Horizontal gene transfer(HGT) of multiple functionally coupled enzymes occurs in E. huxleyi and its DNA virus Eh V has been confirmed, which contributes to the diversification and adaptation of plankton in the oceans and also critically regulates virus-host infection by allowing viruses to control host metabolic pathways for their replication. Therefore, it is of particular interest to understand this host-virus interaction. On this issue, we have made a minireview of coccolithoviruses focusing on the basic characteristics, phylogenesis, horizontal gene transfer and the interaction between the host and its viruses, as well as its important role in global biogeochemical cycling.  相似文献   
9.
For the investigation of anti-infection immune response of Pseudosciaena crocea, 160 healthy fish samples were categorized into infected and control groups. Each individual fish in the infected group was injected intraperitoneally (i.p.) with 0.2 ml bacterial suspension of Vibrio alginolyticus in density of 2×107 CFU/ml, while each individual in the control group was injected i.p. with 0.2 ml sterile saline solution (0.85%). It was observed that the artificial injection of V. alginolyticus significantly inc...  相似文献   
10.
从声波波场理论出发,首先在不考虑自由表面反射的情况下研究了有效波波场传播及反射规律,继而考虑自由表面反射的情况,并详尽推导了压制自由表面多次波的正演和反演数学模型。从物理本质上对自由表面多次波的产生、预测及压制做了深入的剖析,讨论了基于数据一致性时空域褶积的多次波预测方法原理,实现了自由表面相关多次波自适应压制的迭代方法过程。复杂起伏海底的理论模型试算实例表明:在多次波产生系统非常复杂的情况下,本方法仍能非常有效地压制各种与自由表面相关的多次波,同时还能很好地保持有效波的能量,取得了很好的压制多次波效果。  相似文献   
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