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Several environmentally relevant contaminants are characterized as xenoestrogens by virtue of their ability to induce responses similar to 17β-estradiol (E2). There is concern that exposure to these xenoestrogens may result in endocrine and, thus, reproductive disruption. The objective of the present research was to determine whether xenobiotics known to elicit estrogenic responses in mammals were estrogenic in channel catfish, and if these compounds were capable of altering normal physiological response to E2. Sexually immature catfish were exposed by intraperitoneal injection to E2, suspected xenoestrogens or combination doses of E2 and xenoestrogen. Appearance of vitellogenin (Vg) in serum was used as the bioindicator of estrogenicity; Vg was measured by ELISA 7 days after injection. The ED50 of E2 for the appearance of Vg in blood, 0.6 mg/kg, was used as the positive control. Synthetic estrogens, ethinylestradiol, mestranol and DES were effective in inducing Vg; the antiestrogen tamoxifen inhibited response to E2 when given in a combination dose. Treatment by both methoxychlor and p-nonylphenol resulted in Vg appearance in serum; the doses required were 300 times that of E2, and the vitellogenic response was less when compared to the E2-induced response. In addition, a combination dose of methoxychlor with E2 decreased the magnitude of the response to E2. Other mammalian xenoestrogens, o,p′-DDT, chlordecone, lindane and β-HCH, were not able to produce a vitellogenic response in this study.  相似文献   
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The major fisheries on the Pacific coast of Canada can be grouped into 12 species that have consistently represented about 80–90% of the total catch from the past to the present. A review of population dynamics of these species indicates that climate and the ocean environment have a major impact on their productivity. We review the history of Canada's Pacific coast fishery to show that trends in catch were similar to trends in the climate and ocean environment. Decadal scale patterns in climate and the ocean are termed regimes and we show that it is the regime scale of climate variability that most influences the long-term trends in the catches in these major fisheries. Ignoring the impacts of regime shifts on the abundance trends in the future could result in collapses of major fisheries. The difficulty of knowing when a regime shift will occur may be overcome as we discover more about the mechanisms that affect the decadal-scale trends in the rotational velocity of the solid earth which is measured as the length of day (LOD).  相似文献   
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Although the supply and fate of suspended sediment is of fundamental importance to the functioning and morphological evolution of muddy estuaries, reliable sediment budgets have been established in only a few cases. Especially for smaller estuaries, inadequate bathymetric surveys and a lack of intertidal sedimentation data often preclude estimation of the sediment budget from morphological change, while instrument-derived residual fluxes typically lie well within the errors associated with measurement of much larger gross tidal transports. Given suitably long-term records of continuously monitored suspended sediment concentration (SSC), however, analysis of the major scales of variation in sediment transport and their relation to hydrodynamic and meteorological forcing permits qualitative testing of hypotheses suggested by directly measured residual fluxes. This paper analyzes data from a 1-year acoustic Doppler profiler deployment in the Blyth estuary, a muddy mesotidal barrier-enclosed system on the UK east coast. Flux calculations indicate a small sediment import equivalent to just 1.5% of the gross flood tide transport. Little confidence can be assigned to either the magnitude or direction of such a small residual when considered in isolation. However, the inference that the sediment regime is finely balanced is qualitatively supported by the close similarity between flood-tide and ebb-tide SSC values. Singular spectrum analysis of the SSC time series shows the expectedly large contributions to the variance in SSC at intratidal and subtidal (semimonthly and monthly) scales but also picks out intermittent variability that is initially attributed to a combination of non-tidal surge and wind stress forcing. Closer examination of the data through cross-correlograms and event-scale analysis indicates that local meteorological forcing is the major factor. Acting through the resuspension of intertidal mudflat sediments at times of strong westerlies, meteorological forcing is directly implicated in episodic sediment export from the estuary. Thresholding of tide-averaged fluxes using a range of critical wind stress values further indicates that ‘tide-dominated’ (i.e., low wind stress) and ‘wave-dominated’ (high wind stress) conditions are associated with sediment import and export. Sediment balance is potentially sensitive to the frequency of high wind stress events, since the associated sediment exports are several times larger than the average import under calm conditions. Intermittent meteorological forcing may thus exert an important control on the sedimentary balance of otherwise tidally dominated muddy estuarine systems, and the role of wind climate should not be overlooked in studies of estuary response to environmental change.  相似文献   
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Risk and uncertainty assessments for waste containment systems employing clay barriers often include spatial variability in the hydraulic conductivity as part of the analysis. The two-parameter log-normal distribution is often used to describe the spatial variability, but for compacted clays the three-parameter form can be more appropriate. A statistical hypothesis test was developed that can be used to determine if the two- or three-parameter form of the log-normal distribution is more appropriate. The test is based on a likelihood ratio, comparing likelihood functions for the two- and three-parameter forms at their maximums. Likelihood functions are used assuming that a data set can be segregated into a set of distinct groups of hydraulic conductivities. A step-by-step calculation procedure is described and the test is applied to data collected from 45 sites.  相似文献   
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A migration algorithm appropriate for moderately varying lateral velocity changes is developed as an extension of phase-shift migration by using a variable-length spatial transform. This process significantly reduces the number of lateral wave-numbers necessary to downward continue the data, and it replaces the spatial FFT with a simple recursion relationship. For a given frequency and position x, ten lateral wavenumbers are typically sufficient, and the migration algorithm produces accurate images when the velocity structure V (X, z) changes over a few depth intervals of thickness Δz, with lateral velocity gradients up to 1.4 to 1.0.  相似文献   
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Air was injected through a well in a thin transparent tank filled with saturated glass beads to study how the size and air saturation of air sparging plumes are affected by particle size and gradation; operational parameters such as injection pressure, well depth, injection pressure pulsing; and well outlet configuration. V-shaped air plumes with an apex between 40° and 60° were obtained for all tests. The air pressure required to initiate sparging agreed closely with the sum of the air entry pressure and the hydrostatic pressure, with higher initiation pressures required in the fine and well-graded beads. Higher air flow rates and air saturations were obtained in coarser beads at a given pressure, and the variation in flow rate was consistent with estimated air permeabilities. Peak average air saturations were 28–56% for the coarse-medium beads, 10% for the well-graded beads, and 8% for the fine beads. Air saturation and the radius of influence increased modestly (<40%) as the normalized injection pressure exceeded 0.1. Radius of influence increased by approximately a factor of two as the well depth increased, but leveled off once the ratio of radius of influence to well depth reached 0.60–1.05. Pulsing of injection pressure had no effect on the initiation pressure, air flow rate, or air saturation, but increased the size of the air plume and the radius of influence slightly (<15%). Well outlet configuration had only a slight affect the radius of influence (<10%), air saturation (<10%), or air flow rate (<12%). Dye testing showed that water surrounding the air plume circulated during continuous and pulsed sparging. However, pulsed sparging resulted in greater and more defined circulation of water within and adjacent to the air plume, which should reduce mass transfer limitations during sparging.  相似文献   
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This paper presents a new method, called the equivalent force control method, for solving the nonlinear equations of motion in a real‐time substructure test using an implicit time integration algorithm. The method replaces the numerical iteration in implicit integration with a force‐feedback control loop, while displacement control is retained to control the motion of an actuator. The method is formulated in such a way that it represents a unified approach that also encompasses the effective force test method. The accuracy and effectiveness of the method have been demonstrated with numerical simulations of real‐time substructure tests with physical substructures represented by spring and damper elements, respectively. The method has also been validated with actual tests in which a Magnetorheological damper was used as the physical substructure. Copyright © 2007 John Wiley & Sons, Ltd.  相似文献   
10.
—Whereas the coast of Peru south of 10°S is historically accustomed to tsunamigenic earthquakes, the subduction zone north of 10°S has been relatively quiet. On 21 February 1996 at 21:51 GMT (07:51 local time) a large, tsunamigenic earthquake (Harvard estimate M w = 7.5) struck at 9.6°S, 79.6°W, approximately 130 km off the northern coast of Peru, north of the intersection of the Mendaña fracture zone with the Peru–Chile trench. The likely mechanism inferred from seismic data is a low-angle thrust consistent with subduction of the Nazca Plate beneath the South American plate, with relatively slow rupture characteristics. Approximately one hour after the main shock, a damaging tsunami reached the Peruvian coast, resulting in twelve deaths. We report survey measurements, from 7.7°S to 11°S, on maximum runup (2–5m, between 8 and 10°S), maximum inundation distances, which exceeded 500 m, and tsunami sediment deposition patterns. Observations and numerical simulations show that the hydrodynamic characteristics of this event resemble those of the 1992 Nicaragua tsunami. Differences in climate, vegetation and population make these two tsunamis seem more different than they were. This 1996 Chimbote event was the first large (M w >7) subduction-zone (interplate) earthquake between about 8 and 10°S, in Peru, since the 17th century, and bears resemblance to the 1960 (M w 7.6) event at 6.8°S. Together these two events are apparently the only large subduction-zone earthquakes in northern Peru since 1619 (est. latitude 8°S, est. M w 7.8); these two tsunamis also each produced more fatalities than any other tsunami in Peru since the 18th century. We concur with Pelayo and Wiens (1990, 1992) that this subduction zone, in northern Peru, resembles others where the subduction zone is only weakly coupled, and convergence is largely aseismic. Subduction-zone earthquakes, when they occur, are slow, commonly shallow, and originate far from shore (near the tip of the wedge). Thus they are weakly felt, and the ensuing tsunamis are unanticipated by local populations. Although perhaps a borderline case, the Chimbote tsunami clearly is another wake-up example of a "tsunami earthquake."  相似文献   
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