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Excessive alcohol consumption leads to liver disease. Extensive evidence suggests that C-phycocyanin (C-PC), a chromophore phycocyanobilin derived from Spirulina platensis, exerts protective effects against chemical-induced organ damage. In this study, we investigated whether C-PC could protect against ethanol-induced acute liver injury. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (CHOL), low-density lipoprotein (LDL), liver homogenate malondialdehyde (MDA), superoxide dismutase (SOD) content were measured, and pathological examination of liver sections were examined. C-PC showed obvious inhibitory effects on serum ALT, AST, TG, CHOL, LDL and MDA, and SOD content significantly increased in the liver. The structure of hepatic lobules was clear, liver sinus returned to normal, and liver cell cords were arranged in neat rows. Cloudiness, swelling, inflammatory cell infiltration and spotty necrosis of liver cells were significantly reduced. Therefore, C-PC can significantly protect against ethanol-induced acute liver injury. 相似文献
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可持续发展能力评价方法是识别人地协同规律、支撑科学决策的重要工具和热点需求。通过文献回顾与理论分析框架构建,耦合能值及?方法,提出自组织能力指数(SO)、生态压力指数(EP)、可持续发展能力指数(SC)构成的,基于热力学理论的可持续发展能力分析模型,利用文献荟萃法筛选17个典型发达国家1985年状态值计算SO与EP阈值,划分了4个阶段。利用中美两国1985-2015年特征对比验证,结果显示:① 2005年以前中国属“低自组织能力、低生态压力”阶段,之后进入“低自组织能力、高生态压力”阶段,存在低生态效率、规模扩张驱动特征;美国一直属“高自组织能力、高生态压力”阶段,存在高生态效率驱动、经济与生态脱钩特征,与全球生态足迹网络和世界自然基金会等的研究结果一致,模型具有较好适应性和可靠性。② 模型利用“获得?量/输入能值量”表达经济社会生态效率、“经济社会?损耗量/生态系统年产?量”表达生态压力,连接了经济社会对生态基底的熵化路径,可识别区域所处可持续发展阶段、分析水平变化和驱动因素。③ 模型以人类与生态并重的视角,从深度上反映经济社会的生态效率、从广度上评价生态空间被占用比例,具有宏观规模与微观效率分析相结合的优势,是对经典方法的补充。 相似文献
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石家庄市大气PM1、PM2.5和PM10中重金属元素分布特征及来源的对比研究 总被引:1,自引:0,他引:1
为了解元素(尤其是重金属元素)在不同粒径大气颗粒物中的分布规律、污染特征及来源,于2016年在石家庄市采集PM1、PM2.5和PM10样品。利用等离子体质谱仪(ICP-MS)测定了Al、Ti、V、Cr、Mn、Fe、Cu、Zn、As、Sb、Hg、Pb和Cd共13种元素的质量浓度,采用富集因子(EF)法分析各种元素在PM1、PM2.5和PM10中的分布特征,并通过主成分分析法讨论了这些元素的主要来源。富集因子分析显示出Al、Fe、Ti、Mn受人为因素影响较少(EF<10),其他元素则出现显著至极强的人为影响,尤其是Cd元素(EF>103),并发现颗粒物粒径较小时,富集因子较大,即人为因素影响更重。主成分分析表明:PM1中元素有工业冶炼及燃煤活动、机动车燃油排放、生活燃煤3个来源,PM2.5中元素有地壳源、电厂及居民生活燃煤、金属冶炼等工业活动、机动车尾气4个来源,PM10中元素有化石燃料燃烧和地壳源、与机动车相关的道路扬尘及工业尘、垃圾焚烧及机动车排放与磨损、燃煤活动4个来源。 相似文献
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The scattering of plane SH-waves by topographic features in a layered transversely isotropic (TI) half-space is investigated by using an indirect boundary element method (IBEM). Firstly, the anti-plane dynamic stiffness matrix of the layered TI half-space is established and the free fields are solved by using the direct stiffness method. Then, Green’s functions are derived for uniformly distributed loads acting on an inclined line in a layered TI half-space and the scattered fields are constructed with the deduced Green’s functions. Finally, the free fields are added to the scattered ones to obtain the global dynamic responses. The method is verified by comparing results with the published isotropic ones. Both the steady-state and transient dynamic responses are evaluated and discussed. Numerical results in the frequency domain show that surface motions for the TI media can be significantly different from those for the isotropic case, which are strongly dependent on the anisotropy property, incident angle and incident frequency. Results in the time domain show that the material anisotropy has important effects on the maximum duration and maximum amplitudes of the time histories. 相似文献
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本文对东昆仑夏日哈木退变质榴辉岩开展岩石地球化学和年代学研究,探讨其原岩性质和构造背景。岩石SiO2含量为46.77%~49.31%,Al2O3含量为13.6%~14.6%,TiO2含量为0.93%~2.29%,全碱(K2O+Na2O)含量为1.61%~2.66%,原岩属亚碱性玄武岩系列中的拉斑玄武岩。(La/Yb)N=0.98~1.63,(La/Sm)N=0.98~1.41,δEu=1.10~1.28,稀土元素球粒陨石标准化图呈弱Eu正异常的右倾型,岩石相对富集大离子亲石元素Rb、Ba和不相容元素U,相对亏损高场强元素Zr、Hf,Hf/Th=0.59~0.97,Th/Yb=0.13~0.27,显示其原岩具E-MORB特征。退变质榴辉岩的锆石Th/U比值为0.002~0.091,为变质成因锆石,其锆石SIMS U-Pb年龄为414.2 ±7.3 Ma,代表了退变质榴辉岩的峰变质年龄,结合区域地质背景,认为该岩石形成于早泥盆世早期由碰撞作用向碰撞后伸展作用转换的构造环境。 相似文献
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采用间接边界元法(IBEM)结合"分区契合"技术,研究qP波入射下横观各向同性(TI)场地中衬砌隧道的动力响应问题。方法充分利用半空间和全空间动力格林函数在分别构造含孔半无限空间域和闭合域内散射波场方面的优势,将含有衬砌隧道的层状弹性半空间分解为含孔半无限空间域和一个环形衬砌闭合域来分别进行波场构造,有效地降低了求解时间和存储量。文中验证方法的正确性,并以均匀TI半空间和基岩上单一TI土层为例,计算分析弹性半空间场地中隧道衬砌内表面动应力放大问题。结果表明qP波入射下,TI介质与各向同性介质场地中埋置衬砌隧道的动力响应差异显著,TI介质参数的变化导致场地动力特性的改变,进而改变场地与衬砌隧道的动力相互作用机制,显著影响着衬砌内表面动应力的大小及其空间分布。 相似文献
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