Artificial Upwelling of Deep Seawater Using the Perpetual Salt Fountain for Cultivation of Ocean Desert

Deep seawater in the ocean contains a great deal of nutrients. Stommel et al. have proposed the notion of a “perpetual salt fountain” (Stommel et al., 1956). They noted the possibility of a permanent upwelling of deep seawater with no additional external energy source. If we can cause deep seawater to upwell extensively, we can achieve an ocean farm. We have succeeded in measuring the upwelling velocity by an experiment in the Mariana Trench area using a special measurement system. A 0.3 m diameter, 280 m long soft pipe made of PVC sheet was used in the experiment. The measured data, a verification experiment, and numerical simulation results, gave an estimate of upwelling velocity of 212 m/day. This revised version was published online in July 2006 with corrections to the Cover Date.     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

人工神经网络在地质学判别分析中的应用

将现代人工神经网络方法应用于地质学的判别分析，通过实例计算表明，无论是对于两组判别分析还是多组判别分析，人工神经网络方法都是切实可行的。     

A Linear Programming Model for Seabed Oil-Gas Pipe Network

This paper analyzes the pipe network system of oil-gas collection and transportation foroffshore oilfield development.A"0-1"integer linear programming model is constructed to optimize theinvestment of seabed pipe network.The mathematical model is solved by the spanning tree method ofgraph theory and network analysis.All spanning trees of a network graph compose all the feasible solu-tions of the mathematical model.The optimal solution of the model is the spanning tree with the minimumcost among all spanning trees.This method can be used to optimize the seabed pipe network system andgive a minimum cost plan for the development of offshore marginal oilfield groups.     

排铅奶粉对在岗交警体内粪铅排除作用

研究了青岛市南、市北、四方三区交警在服用排铅奶粉（ＬｅａｄＥｘｃｒｅｔｉｎｇＭｉｌｋＰｏｗ－ｄｅｒ，ＬＥＭＰ）前后，体内粪铅含量变化情况。实验结果表明，服用ＬＥＭＰ后，粪铅含量先呈上升趋势，达到最高值后，又呈下降趋势。在整个实验过程中，粪铅含量四方区最高，而市南区最低。服用ＬＥＭＰ前，三区交警粪铅平均含量为０．６８７ｍｇ／ｋｇ，服用７ｄ后达到峰值（１．９６ｍｇ／ｋｇ，Ｐ＜０．０１），第１５ｄ降到１．６１（ｍｇ／ｋｇ）（Ｐ＜０．０５），表明ＬＥＭＰ能排除体内铅起到预防铅中毒的作用     

Pressure prediction in the Bullwinkle Basin through petrophysics and flow modeling (Green Canyon 65, Gulf of Mexico)

Reservoir pressures within the Bullwinkle minibasin (Green Canyon 65, Gulf of Mexico continental slope) increase at a hydrostatic gradient whereas pressures predicted from porosity within mudstones bounding these reservoirs increase at a lithostatic gradient: they are equal at a depth 1/3 of the way down from the crest of the structure. Two- and three-dimensional steady-state flow models demonstrate that bowl-shaped structures will have lower pressures than equivalent two-dimensional structures and that if a low permeability salt layer underlies the basin, the pressure is reduced. We conclude that at Bullwinkle, pressure is reduced due to an underlying salt body and the bowl-shape of the basin. A geometric approach to predict sandstone pressure is to assume that the reservoir pressure equals the area-weighted average of the mudstone pressure. When the mudstone pressure gradient is constant, as at Bullwinkle, the reservoir pressure equals the mudstone pressure at the average depth (centroid) of the reservoir.     

Responses of a Mediterranean soft bottom community to short-term (1993-1996) hydrological changes in the Rhone river

The polychaete fauna of muddy bottoms off the Rhone delta (NW Mediterranean) was seasonally sampled at two sites at 70 m depth, from 1993 to 1996. During this period, five severe flood events occurred. A clustering analysis (distance coefficient of Whittaker) and three way fixed factor ANOVAs (site x season x year) showed strong year-to-year changes in species density and community structure, changes that masked seasonal variations. Total density increased by a factor of 3 and density of most species significantly increased following the first flooding event. Changes in the community structure were due to the successive dominance of a few species. The opportunistic species, such as Cossura sp., Mediomastus sp. and Polycirrus sp., exhibited peaks in density 1-3 months after the flood. These peaks were followed by a drastic decline. For species with a long life span, such as Sternaspis scutata, a slower but continuous increase in density was observed which was maintained for several months. The density fluctuations of these species exhibited a good correlation with river flow with time lags of 1-2 years. The successional dynamics observed are explained according to the geographical origin of the floods and the biology and feeding ecology of species.     

A Numerical Study on the Structure and Dynamics of Turbulence in Oscillatory Bottom Layer Flow over A Flat or Rippled Bed

1 .IntroductionUnder the influence of surface waves ,sandripples often appear on beaches . Whenthe amplitudeof water oscillationis sufficientlylarge ,vortices are formed onthe lee of every sand ripple crest . A-mongthese vortices ,the most important are t…     

Numerical study of enhanced energy dissipation near a seamount

Using a two-dimensional primitive equation model, we examine nonlinear responses of a semidiurnal tidal flow impinging on a seamount with a background Garrett-Munk-like (GM-like) internal wavefield. It is found that horizontally elongated pancake-like structures of high vertical wavenumber near-inertial current shear are created both in the near-field (the region over the slope of the seamount) and far-field (the region over the flat bottom of the ocean). An important distinction is that the high vertical wavenumber near-inertial current shear is amplified only at mid-latitudes in the far-field (owing to a parametric subharmonic instability (PSI)), whereas it is amplified both at mid-and high-latitudes (above the latitude where PSI can occur) in the near-field. In order to clarify the generating mechanism for the strong shear in the near-field, additional numerical experiments are carried out with the GM-like background internal waves removed. The experiments show that the strong shear is also created, indicating that it is not caused by the interaction between the background GM-like internal waves and the semidiurnal internal tides. One possible explanation is proposed for the amplification of high vertical wavenumber near-inertial current shear in the near-field where tide residual flow resulting from tide-topography interaction plays an important role in transferring energy from high-mode internal tides to near-inertial internal waves.     

黄河断流对河口空间场后效反馈的遥感复合信息研究

就黄河断流对河口空间场后效所涉及的地理要素的演变,以所建河口演变概念-遥感信息系统,分析研究了黄河口近期演变的互关联信息基础,并依据研究目标的信息需求分析(IRA)与水下地貌趋势面分析的结果,阐述了河口空间场诸种反馈信息、变异中直观信息及隐伏信息.