Anti-inflammatory and Immunomodulatory Effects of Marine n-3 Polyunsaturated Fatty Acids on Human Health and Diseases

The pharmaceutical effects of n-3 polyunsaturated fatty acids(n-3 PUFAs) as dietary nutrients on human health and diseases have gained much attention and are investigated for decades. Docosahexaenoic acid(DHA), eicosapentaenoic acid(EPA) and docosapentaenoic acid(DPA) are the three major n-3 PUFAs enriched in marine organisms, such as fish, shrimp, algae, and so on. It has been well known that n-3 PUFAs, especially DHA and EPA, are beneficial in reducing the risk of cardiovascular and cerebrovascular diseases. Accumulating evidence suggests that n-3 PUFAs might cure inflammatory diseases through several mechanisms, such as plasma membrane remodeling of lymphocytes, down-regulating pro-inflammatory cytokines, and alternating adhesion molecule expressions. Several molecular targets of n-3 PUFAs on immune-regulation have also been identified, such as GPR120(FFA4), protein kinase C(PKC), and PPAR-γ. However, it remains inconclusive if dietary n-3 PUFAs function the same both in vitro and in vivo based on cohort studies. This review will focus on the molecular targets and mechanisms of anti-inflammatory and immunomodulatory effects of n-3 PUFAs on human health and diseases, such as obesity, tumor, diabetes, and autoimmune diseases.     

土壤粒径的光谱响应特性研究

以实验室制备的5个不同粒径水平的土壤样本和室内高光谱数据为基础,通过对光谱数据进行重采样、数学变换等预处理并进行单因素方差分析、相关性分析和回归分析,探讨土壤粒径的高光谱特性,建立了光谱数据预测土壤粒径的校正模型。结果表明,土壤粒径对反射光谱有显著的影响,波长越长影响越大;在全波段范围内土壤粒径和光谱数据都呈负相关关系,对原始光谱数据进行微分变换能增加其与土壤粒径的相关性;以反射率一阶微分建立的回归模型为反演土壤粒径的最佳模型,其建模决定系数■、预测决定系数■、预测相对偏差RPD分别为0.666,0.653,2.043,预测均方根误差RMSE为0.175。     

中国半干旱草原施氮梯度下的土壤激发效应（英文）

为了探究施氮对土壤有机质(SOM)的激发效应,本研究在施氮梯度样地(0、4和16 g N m^–2 yr^–1)上进行了¹³C标记葡萄糖的原位添加实验,并对土壤CO_2排放量和磷脂脂肪酸(PLFA)含量进行了测定。研究发现施氮降低了土壤CO_2排放、土壤PLFA含量以及土壤真菌细菌比。在0 g N m^–2 yr^–1样地上葡萄糖添加导致的正向激发效应最强,同时4 g N m^–2 yr^–1样地释放的葡萄糖来源的碳最多。因此,施氮减少了土壤中SOM转化产生的CO_2,微生物碳的来源由SOM转变为添加的易分解碳。本研究采样早期土壤微生物生物量和群落结构稳定,表明该草原存在"表观激发效应",因此未来研究应着重对微生物功能的多样性进行探讨。     

Reliability of mooring lines and piles for a permanently manned vessel in a tropical cyclone environment

The factors of safety for stationkeeping systems in current standards (ISO, API) are not derived or validated using reliability analyses. As the oil and gas exploration and production is breaking new boundaries, deploying new floating systems and moving into regions with harsher environments, it is of paramount importance to understand what level of reliability these new marine structures are achieving. This paper presents a reliability analysis of the mooring system of a Floating LNG (FLNG) vessel permanently moored and permanently manned offshore North West Australia in a tropical cyclone environment. The reliability analysis addresses both the mooring chain and the pile foundation. The analysis accounts for the long term characteristics of the environment, including the short term variability, in response to a given sea state and the variability and uncertainty in strength of the mooring chain and the pile. The stationkeeping system was analysed using detailed time domain simulations, capturing system non-linearities and low frequency oscillations as well as wave frequency responses and, thereby, reducing modelling uncertainties to a minimum.It is found that for the conditions modelled, neither the chain nor the pile meet a target reliability of 10⁻⁴/annum using the factors of safety commonly used in design following current ISO and API standards. New factors of safety are proposed to achieve this target reliability. For the pile design, one complicating factor is that current design standards do not explicitly define the exceedance probability that should be associated with the characteristic value of the undrained shear strength to be used in the design. It is demonstrated that the required factor of safety is crucially dependent on the definition of this characteristic value and on the level and the type of uncertainty in the soil strength profile. A recommendation is made regarding the definition of this characteristic value and the associated factor of safety. Furthermore, it is found that designing the mooring system to an environmental condition with a return period of 10,000 yr (as an Abnormal Limit State event), and setting the factor of safety to unity, meets the target reliability of 10⁻⁴/annum for the pile, if the characteristic undrained shear strength is a lower bound, defined in this paper by the 10th percentile value. For the chain however, this target reliability is not achieved.     

拟穴青蟹(Scylla paramamosain)六个地理群体肌肉氨基酸和脂肪酸的比较分析

本文对广西钦州(Gq)、福建霞浦(Fx)、浙江温州(Zw)、浙江三门(Zs)、浙江宁海(Zn)、浙江慈溪(Zc)等6个野生群体拟穴青蟹(Scylla paramamosain)肌肉进行了氨基酸及脂肪酸分析。共测定出19种游离氨基酸和26种脂肪酸。氨基酸含量在80.94—191.39mg/g之间, Gq为最高;总脂肪酸含量在7.97—11.38mg/g之间,Zn为最高。主要氨基酸为甘氨酸和精氨酸;主要脂肪酸为C20:5n3(EPA),占总脂肪酸含量的平均值为(22.47±5.84)%。各群体风味氨基酸和多不饱和脂肪酸含量丰富,占总氨基酸比例(TDAA/TFAA)和总脂肪酸比例(PUFA/TFA)分别为(53.62±5.43)%和(59.27±5.29)%。Zs群体的必需氨基酸含量及C22:6n3(DHA)均为最高。主成分分析结果表明:各群体的氨基酸与脂肪酸组成与含量相似性与地理距离分布具有一定的相关性,特别是Gq群体,在氨基酸与脂肪酸的分类中与其他群体区分比较明显。各群体风味氨基酸和多不饱和脂肪酸的聚类分析结果均表明:Zw、Zc与Gq群体较为接近,具有较强的甜味; Fx、Zn与Zs群体较为接近,具有较强的香味及不饱和脂肪酸营养价值。     

人工冻土观测的冻点对应的土壤温度研究

基于2018年12月至2020年3月喀左、沈阳、辽阳、满洲里4个国家级地面气象站人工冻土器与测温式冻土自动观测仪观测的资料,对人工冻土观测获得的冻点与测温式冻土自动观测仪获得的相应深度的温度进行对比分析.结果表明:人工冻土器获取的冻点对应的土壤温度与0℃总体一致,又不完全重合;0—35 cm深度范围,冻点对应的温度变化...     

利用气象要素计算五道梁地区土壤热流量的试验

根据五道梁地区1994—1997年的热流板测量土壤热流值,初步分析了该地区土壤热流随时间的变化特征。利用1994—1996年的月平均资料分别分析了总辐射、地表温度、地表温度和80 cm深度温度差和2 cm、10 cm深度的土壤热流的相关性,并建立了相应的回归方程;利用得到的回归方程对1997年的土壤热流作计算检验,就月平均资料来说,用总辐射和地温差来计算浅层土壤热流结果是比较可靠的。     

广西农业干旱动态评估模型

以自然条件下大气-作物-土壤系统的水量平衡方程为基础,结合广西干旱灾害特点,建立广西农业干旱评估模型。与广西历史农业旱情实况对比分析表明,该模型能够较客观、定量地对农业干旱的发生、发展过程进行逐日动态监测和灾中、灾后评估。     

土氡测量在海口市活动断层探测中的初步应用

运用土壤氡射气(土氡)测量方法对海口市的六条隐伏断层进行探测,检验土壤氡射气(土氡)测量在海口市地区的有效性,结果表明,土氡测量探测晚更新世(Q3)和全新世(Q4)隐伏断层具有较好的效果,可以作为海口市活动断层探测一种有效手段。     

利用反射GPS信号遥感土壤湿度

在水文、气候、农业等问题的研究中,土壤湿度信息十分重要。近年来,利用GPS系统进行遥感的新方法,已经越来越多地引起研究者们的关注。特别是GPS卫星广播的L1（1.57542GHz）频率信号,是土壤湿度遥感的最佳频率。反射GPS信号功率是土壤介电常数的函数,而土壤介电常数又和土壤湿度有关。根据这一原理,美国国家航空与航天局于2002年进行了基于地表面反射GPS信号的遥感土壤湿度实验。结果证明反射GPS信号对土壤湿度特性十分敏感,由于植被的影响对反射率进行了修正,并用此方法模型与其它方法进行了比较。在利用GPS遥感土壤湿度方面,研制高增益天线,更好的修正信号波动的影响,发展更加完善的遥感土壤湿度方法等是今后在此项研究中所要解决的问题。