几丁糖酯原料药稳定性研究

该文建立高效凝胶渗透色谱法 (HPGPC) ,明胶比浊法 ,氧瓶燃烧法三种分析方法考察海洋硫酸多糖药物几丁糖酯的稳定性 ,采用这三种方法分别考察几丁糖酯原料药在高温、高湿、强光照射及加速条件下分子量及分布宽度、样品中硫酸根含量及样品含量的变化情况。结果表明 :三种方法均适用于几丁糖酯的稳定性考察 ,几丁糖酯在上述影响因素条件下稳定性良好     

Seasonal variations of water system distribution and flow patterns in the southern sea area of Hokkaido,Japan

Hydrographic data and composite current velocity data (ADCP and GEK) were used to examine the seasonal variations of upper-ocean flow in the southern sea area of Hokkaido, which includes the “off-Doto” and “Hidaka Bay” areas separated by Cape Erimo. During the heating season (April–September), the outflow of the Tsugaru Warm Current (TWC) from the Tsugaru Strait first extends north-eastward, and then one branch of TWC turns to the west along the shelf slope after it approaches the Hidaka Shelf. The main flow of TWC evolves continuously, extending eastward as far as the area off Cape Erimo. In the late cooling season (January–March), part of the Oyashio enters Hidaka Bay along the shallower part of the shelf slope through the area off Cape Erimo, replacing almost all of the TWC water, and hence the TWC devolves. It is suggested that the bottom-controlled barotropic flow of the Oyashio, which may be caused by the small density difference between the Oyashio and the TWC waters and the southward migration of main front of TWC, permits the Oyashio water to intrude along the Hidaka shelf slope.     

东南沿海海堤现状调研报告（福建部分）

这部分是福建省正在建设中的四大海堤现状调研，包括达标设计各项指标及其加高加固的技术经验。同时调研了围海工程堵口海堤的施工过程，并对灌砂防渗措施加以评述。最后介绍了兴化湾的莆田海堤试验站和木兰陂水利工程     

比较原理在多有理数时滞区间系数离散系统的应用

应用多组有理数时滞离散系统的比较原理和频域法,将多组有理数时滞区间系数离散系统化为多组有理数时滞定常离散系统,以判定其时滞无关稳定性,并举例说明了新定理的有效性和实用性。     

水动力作用下管道稳定性的试验研究

利用振荡流水槽在以下两种约束条件下，研究波浪作用下直接铺设于砂质海底的管道失稳临界条件：1）管道两端自由；2）管道可水平、垂直自由运动，但流动受到限制。试验结果表明，管重无量纳数G与管道失稳的临界Fr数之间大致呈线性关系，而当G超过一定数值时，管道是侧向稳定的。管道的约束条件、砂床特性和加载速度对管道稳定性均有影响。     

Spatial Modeling and Analysis for Shoreline Change Detection and Coastal Erosion Monitoring

Coastal erosion presents a serious problem throughout U.S. coastal areas. The Ohio Geological Survey estimates that more than 3,200 acres of Ohio's Lake Erie shore have been lost to erosion since the 1870s, resulting in economic losses exceeding tens of millions of dollars per year. This article presents research results of a project that monitors shoreline erosion using high-resolution imagery and examines erosion causes. Spatial modeling and analysis methods are applied to the project area along the south shore of Lake Erie. The shoreline is represented as a dynamically-segmented linear model that is linked to a large amount of data describing shoreline changes. A new method computes an instantaneous shoreline using a digital water level model, a coastal terrain model, and bathymetric data. This method provides an algorithm for deriving the Mean-Lower Low Water (MLLW) and the Mean High Water (MHW) shorelines that are essential to navigation charts. The results describe a part of our effort towards a coastal spatial information infrastructure to support management and decision-making in the dynamic coastal environment.     

Trace metals in the Western Pacific: temporal and spatial variability in the concentrations of Cd, Cu, Mn and Ni

Profiles of total dissolvable Cd, Cu, Mn and Ni are reported for samples collected from the southwest Pacific in 1989, from the western equatorial Pacific along 155°E at 5°S, 0° and 5°N in 1990 and 1993, and along the equator from 143°E to 152°E and in the Bismarck Sea in 1997 and 2000. Profiles of Cd along 155°E in 1990 and along the equator were essentially the same but, in 1993, Cd values at 5°N were higher by a factor of about 1.5–2 than at 5°S over the depth range 500–1500 m. Similar, but less pronounced, differences were observed for PO₄ and Ni. Cd and Ni were both strongly correlated with PO₄, and an even stronger correlation was found between Ni and Cd. The concentration of Ni did not fall below ≈2 nmolkg⁻¹, even in the nitrate-depleted waters of the western equatorial Pacific, where primary production is strongly dependent on recycled nitrogen (mainly ammonia and urea). It is proposed that this residual Ni is not bioavailable and that Ni could be biolimiting, since the metabolism of urea requires the nickel-containing enzyme urease. The impact of the Sepik River on Cd, Cu and Ni concentrations was small but elevated concentrations of Mn were observed near the Sepik River and close to the coast suggesting that the rivers and sediments on the north coast of New Guinea are a significant local source of Mn to the Bismarck Sea. Simple mass balance calculations show that the elevated levels of Mn observed in the Equatorial Undercurrent cannot be due to input from the rivers of New Guinea and they were attributed to the trapping of particulate matter due to strong current shear. A strong hydrothermal source of Mn was observed in the central Bismarck Sea.     

海岸工程中海浪数值模拟和环境参数选取的进展

主要介绍了我国近的来在海岸工程设计，建设中有关海浪数值模拟及环境参数选取方面的研究进展。     

Circulation and Brackish Water Dispersal in a Coastal Lagoon of Southwest Taiwan

Modest observations and numerical experiments were conducted to investigate circulation and brackish water dispersal in a coastal lagoon southwest of Taiwan. The Chi-Ku Lagoon, partially shielded from the sea by a string of sandbar barriers with two entrances among them, receives modest and episodic runoff from Chi-Ku Stream. Flood and ebb tidal streams entering and leaving the two entrances are found to converge and diverge in a flow stagnation area inside the lagoon. Under weak wind conditions, brackish water is preferentially retained in the flow stagnation area. Besides the observations, scenario runs using a three-dimensional numerical model also indicate strong modulation by monsoon winds. Both summer southwest monsoon and winter northeast monsoon reduce brackish water retention; the latter is found to be more effective. This revised version was published online in August 2006 with corrections to the Cover Date.     

Manganese and iron distributions off central California influenced by upwelling and shelf width

In July 2002, a combination of underway mapping and discrete profiles revealed significant along-shore variability in the concentrations of manganese and iron in the vicinity of Monterey Bay, California. Both metals had lower concentrations in surface waters south of Monterey Bay, where the shelf is about 2.5 km wide, than north of Monterey Bay, where the shelf is about 10 km wide. During non-upwelling conditions over the northern broad shelf, dissolvable iron concentrations measured underway in surface waters reached 3.5 nmol L⁻¹ and dissolved manganese reached 25 nmol L⁻¹. In contrast, during non-upwelling conditions over the southern narrow shelf, dissolvable iron concentrations in surface waters were less than 1 nmol L⁻¹ and dissolved manganese concentrations were less than 5 nmol L⁻¹. A pair of vertical profiles at 1000 m water depth collected during an upwelling event showed dissolved manganese concentrations of 10 decreasing to 2 nmol L⁻¹, and dissolvable iron concentrations of 12–20 nmol L⁻¹ in the upper 100 m in the north, compared to 3.5–2 nmol L⁻¹ Mn and 0.6 nmol L⁻¹ Fe in the upper 100 m in the south, suggesting the effect of shelf width influences the chemistry of waters beyond the shelf.These observations are consistent with current understanding of the mechanism of iron supply to coastal upwelling systems: Iron from shelf sediments, predominantly associated with particles greater than 20 μm, is brought to the surface during upwelling conditions. We hypothesize that manganese oxides are brought to the surface with upwelling and are then reduced to dissolved manganese, perhaps by photoreduction, following a lag after upwelling.Greater phytoplankton biomass, primary productivity, and nutrient drawdown were observed over the broad shelf, consistent with the greater supply of iron. Incubation experiments conducted 20 km offshore in both regions, during a period of wind relaxation, confirm the potential of these sites to become limited by iron. There was no additional growth response when copper, manganese or cobalt was added in addition to iron. The growth response of surface water incubated with bottom sediment (4 nmol L⁻¹ dissolvable Fe) was slightly greater than in control incubations, but less than in the presence of 4 nmol L⁻¹ dissolved iron. This may indicate that dissolvable iron is not as bioavailable as dissolved iron, although the influence of additional inhibitory elements in the sediment cannot be ruled out.