Stress Sharing Behavior and Its Mechanism during Consolidation Process in Composite Ground Improved by Sand Compaction Piles with Low Replacement Area Ratio

In order to accurately design a sand compaction pile (SCP) with low replacement area ratio, it is important to understand the mechanical interaction between the sand pile and clay ground and its mechanism during consolidation process in composite ground. In this article, therefore, a series of numerical analyses on composite ground improved by SCP with low replacement area ratio were carried out. The applicability of numerical analyses, in which an elasto-viscoplastic consolidation finite element method was applied, were confirmed by comparing the results obtained from a series of laboratory model tests with the composite ground improved by SCP. Through the results of the numerical analyses, mechanical behavior of the sand pile and clay in composite ground during consolidation is elucidated, together with a stress sharing mechanism between sand pile and clay.     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

黄河口及渤海中南部沉积物工程特性及其机理

采用Ｋａｓｔｅｎ取样器从黄河口及渤海湾中南部海底沉积物中取样，对样品通过土工性质、微结构研究以及粘土矿物分析，阐明本研究区三维空间展布的海底沉积物形成机理及其工程地质规律，论证水动力作用和斜坡不稳定性对工程特性和微结构的重要影响．     

秦皇岛昌黎黄金海岸的沙丘沉积和发育机理

昌黎黄金海岸长40km，分布1～1．5km宽的风成沙丘。主沙丘链高30～40m，顺岸线分布，与其斜交数列新月形横向沙丘链。沙丘以中细砂组成，分选极好，层理构造十分丰富。距今3～4ka以前，沙坝形成时就开始形成沙丘；1915年滦河新三角洲发育以来增加了风沙的输沙量，增高沙丘和扩宽了沙丘带。     

黄河三角洲河道沉积规律研究Ⅱ. 建林边滩沉积作用机理

通过对建林边滩沉积物粒度分布、粒度参数及水体流变性质的分析，阐述了黄河三角洲上河道水流属于牵引流范畴，与低含沙水流无本质上的差别，并探讨沉积物搬运和沉积的基本特征。     

Summer Arctic sea fog

I~IOXSea fog is a kind of dangerous weather. Chinese sea fog experts, Wang Binhua (1983),Hu Ruijin and Zhou Faxiu (1998) and Hu Jifu et al. (1996) studied sea fog rather Systematically. FOreign Experts also Paid great attention to sea fog. Ernlnons and Montgomery(1974), chipper (1994) and Rayrnond et al. (1989) have studied sea fog thorOUghly.HOwever, studies on Arctic sea ice have rarely been carried Out becauSe of the sever environment and less htnnan activity in the region. There …     

黄骅沿海赤潮发生机制的初步探讨

报道了黄骅沿海赤潮发生的过程和形成赤潮的生物种类及造成的危害,并对赤潮成因作了初步分析。     

台湾海峡及其西边地区正常地震动态及危险性特征

本文从地震的时，空分布特征，区域应力场动态，能量释放方式，ｂ值及震群特征６个方面研究了台湾海峡及其西边地区地震活动的正常动态及异常特征。结果表明，具有前兆意义的变化模式表现为区域地震活动在时间，空间及功能方面的有序性变化，即：（ａ）地震空间分布由分散转为集中，形成条带或空区；（ｂ）断裂活动由多组转为单一，应力场趋向一致；（display status