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螺旋藻多糖对肿瘤细胞生长及Hela细胞早期凋亡作用的实验研究 总被引:1,自引:0,他引:1
采用MTT法(四甲基偶氮唑盐比色法)研究了钝顶螺旋藻多糖(PSP)对Hela细胞及HepG2细胞生长的抑制作用。结果表明,随PSP浓度及培养时间的增加,肿瘤细胞存活率逐渐降低,抑制率逐渐增加,以PSP40 mg/L作用72 h最为显著。应用Annexin V/PI双染色流式细胞仪检测了早期Hela细胞凋亡,未经PSP处理的正常Hela细胞凋亡细胞极少,经PSP处理的细胞,凋亡细胞的百分比明显高于正常对照组,其作用随着剂量的增加和时间的延长而增强,具有量效关系和时效关系。结果说明PSP的抗肿瘤机制,除了诱导肿瘤细胞凋亡,还存在细胞毒性等其他机制,是多种机制共同作用的结果。 相似文献
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The proper motions of stars in the main sequence and of luminosity class III giants are analyzed kinematically. A new method has been used for reliably separating all the parameters of the Ogorodnikov-Milne model based on representing the proper motions of the stars in coordinate systems whose poles lie on each of the three principal axes of the galactic trihedron. Solutions for stars in different spectral classes are obtained. The main sequence is found to subdivide into two zones (near and far stars) with a fairly sharp boundary at B-V=0.5. It is shown that the Parenago effect may be related to the different distances from the sun of the main sequence stars. 相似文献
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Manjari Bagchi Rachid Ouyed Jan Staff Subharthi Ray Mira Dey † Jishnu Dey ‡ 《Monthly notices of the Royal Astronomical Society》2008,387(1):115-120
We study the effects of temperature on strange stars. It is found that the maximum mass of the star decreases with the increase of temperature, as at high temperatures the equations of state become softer. Moreover, if the temperature of a strange star increases, keeping its baryon number fixed, its gravitational mass increases and its radius decreases. This leads to a limiting temperature, where it turns into a black hole. These features are the result of a combined effect of the change of gluon mass and the quark distribution with temperature. We report on a new type of radial oscillation of strange stars, driven by what we call 'chromothermal' instability. We also discuss the relevance of our findings in the astrophysics of core collapse supernovae and gamma-ray bursts. 相似文献
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GAO Jianyun CHEN Li WANG Jiaji 《中国科学院上海天文台年刊》2005,(1):60-78
利用上海天文台相隔35年的两期照相底片资料,测定了疏散星团NGC2244所在天区55’×55’范围内495颗恒星基于Tycho-2星表的位置和绝对自行,并对自行精度作了初步分析。 相似文献
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Chris Koen 《Monthly notices of the Royal Astronomical Society》2000,316(3):613-620
One of the tools used to identify the pulsation modes of stars is a comparison of the amplitudes and phases as observed photometrically at different wavelengths. Proper application of the method requires that the errors on the measured quantities, and the correlations between them, be known (or at least estimated). It is assumed that contemporaneous measurements of the light intensity of a pulsating star are obtained in several wavebands. It is also assumed that the measurements are regularly spaced in time, although there may be missing observations. The amplitude and phase of the pulsation are estimated separately for each of the wavebands, and amplitude ratios and phase differences are calculated. A general scheme for estimating the covariance matrix of the amplitude ratios and phase differences is described. The first step is to fit a time series to the residuals after pre-whitening the observations by the best-fitting sinusoid. The residuals are then cross-correlated to study the interdependence between the errors in the different wavebands. Once the multivariate time-series structure can be modelled, the covariance matrix can be found by bootstrapping. An illustrative application is described in detail. 相似文献