Evaluation of the biological toxicity of lfuorine in Antarctic krill

Antarctic krill is a potentially nutritious food source for humans, but lfuorine （F） toxicity is a matter of concern. To evaluate the toxicity of F in Antarctic krill, 30 Wistar rats were divided into three groups with different dietary regimens：a control group, a krill treatment group （150 mg＆#183;kg-1 F）, and a sodium lfuoride （NaF） treatment group （150 mg＆#183;kg-1 F）. After three months, F concentrations in feces, plasma, and bone were determined, and the degree of dental and skeletal lfuorosis was assessed. The F concentrations in plasma and bone from the krill treatment group were 0.167 0＆#177;0.020 4 mg.L-1 and 2 709.8＆#177;301.9 mg＆#183;kg-1, respectively, compared with 0.043 8＆#177;0.005 5 mg＆#183;L-1 and 442.4＆#177;60.7 mg＆#183;kg-1, respectively, in samples from the control group. Concentrations of F in plasma and bone in the krill treatment group were higher than in the control group, but lower than in the NaF treatment group. The degree of dental lfuorosis in the krill treatment group was moderate, compared with severe in the NaF treatment group and normal in the control group. The degree of skeletal lfuorosis did not change signiifcantly in any group. These results showed that the toxicity of F in Antarctic krill was lower than for an equivalent concentration of F in NaF, but it was toxic for rats consuming krill in large quantities. To conclude, we discuss possible reasons for the reduced toxicity of F in Antarctic krill. The present study provides a direct toxicological reference for the consideration of Antarctic krill for human consumption.     

一种基于Harris角点检测的SVG转换可视化效果评价方法

SVG作为移动互联时代获得各种丰富图形信息的有效表达方法,已成为LBS中空间信息表达与描述的热点应用之一,但目前的研究大多没有考虑多源数据格式向SVG格式转换后的图像质量评价问题。针对多源空间数据向SVG格式转换方法和转换效果评价技术,本文设计了栅格数据和矢量数据向SVG格式转换的表达方法,分别利用直接载入栅格图像和编程实现矢量数据转换的方法实现了多源空间数据向SVG格式的有效转换;从定性与定量相结合的角度分析了转换前后的图像质量,设计了角点检测评价指标和流程,提出了基于Harris角点检测的SVG转换前后图形几何质量的评价方法。实验证明:SVG格式比较适用于位置服务中对空间数据尤其是矢量数据的表达,经过SVG转换后的图像,无论是栅格数据还是矢量数据都具有较高的图像质量,且栅格数据的转换效果相对略差于矢量数据;验证了一种基于SVG的移动位置空间服务信息表达和组织模式,对普及和强化SVG在位置服务系统中的应用具有一定的推动作用。     

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Distributed fiber optic monitoring and stability analysis of a model slope under surcharge loading

In the discipline of geotechnical engineering, fiber optic sensor based distributed monitoring has played an increasingly important role over the past few decades. Compared with conventional sensors, fiber optic sensors have a variety of exclusive advantages, such as smaller size, higher precision, and better corrosion resistance. These innovative monitoring technologies have been successfully applied for performance monitoring of geo-structures and early warning of potential geo- hazards around the world. In order to investigate their ability to monitor slope stability problems, a medium-sized model of soil nailed slope has been constructed in laboratory. The fully distributed Brillouin optical time-domain analysis （BOTDA） sensing technology was employed to measure the horizontal strain distributions inside the model slope. During model construction, a specially designed strain sensing fiber was buried in the soil mass. Afterward, the surcharge loading was applied on the slope crest in stages using hydraulic jacks and a reaction frame. During testing, an NBX-6o5o BOTDA sensing interrogator was used to collect the fiber optic sensing data. The test results have been analyzed in detail, which shows that the fiber optic sensors can capture the progressive deformation and failure pattern of the model slope. The limit equilibrium analyses were also conducted to obtain the factors ofsafety of the slope under different surface loadings. It is found that the characteristic maximum strains can reflect the stability of the model slope and an empirical relationship was obtained, This study verified the effectiveness of the distributed BOTDA sensing technology in performance monitoring of slope.     

安徽铜山铜(金)矿床锆石U-Pb年代学和Hf同位素地球化学

安徽池州的铜山岩体是长江中下游地区沿江岩浆岩主带中的含矿岩体之一,其形成年龄及岩石成因尚存在争议。该岩体主要由石英闪长玢岩、石英二长斑岩和花岗闪长岩组成,与铜金矿化关系密切。对铜山矽卡岩型铜(金)矿床的花岗闪长岩开展了锆石U-Pb定年和Hf同位素地球化学研究。岩石地球化学及同位素年代学研究结果表明:花岗闪长岩侵入年龄为(146.3±3.2)Ma,形成于早白垩世;锆石εHf(t)值平均为-5.23,说明铜山侵入岩具有壳幔混合的岩浆岩源区性质;锆石的二阶段Hf模式年龄分布在1 184.51~1 422.72Ma之间,说明岩浆源区与皖南地区出露的中元古代基底有密切关系。构造判别图解显示,铜山岩体属火山弧花岗岩,与长江中下游铜金矿床含矿岩体形成于同一构造背景下,据此推测铜山地区大地构造背景形成于与古太平洋板块俯冲密切相关的大陆边缘岩浆弧环境。     

青海德尔尼铜(钴)矿床矿石矿物特征及其地质意义

青海德尔尼铜(钴)矿床赋存于东昆仑阿尼玛卿蛇绿岩套中部,岩石类型主要有蛇纹石化的方辉橄榄岩、纯橄榄岩和二辉橄榄岩,矿石类型主要为块状、条带状含铜黄铁矿矿石,矿床成因存在多种认识。通过野外详细观察、室内显微镜下矿石矿物特征鉴定以及电子探针分析,确定德尔尼铜(钴)矿床的矿石矿物主要为黄铁矿,其次为磁铁矿、磁黄铁矿、黄铜矿、闪锌矿和方铅矿等,矿石结构以半自形粒状结构为主;钴元素在早期黄铁矿中比较富集,晚期黄铁矿中较贫,w(Co)/w(Ni)值指示黄铁矿与巴西Sossego铁氧化物-铜-金矿一致;早期黄铁矿、黄铜矿、闪锌矿的微量元素质量比值指示矿床成矿温度为200℃~300℃,属于中温环境,进一步证明了该矿床不是岩浆型矿床,属于海底喷流-沉积成因。矿床成矿过程可划分为4个阶段:海底喷流-沉积阶段、构造变形阶段、热液阶段和表生氧化阶段,其中前两个阶段为铜、钴、锌的主要成矿期。     

不同前处理方法对微拟球藻脂肪酸组成的影响

采用直接甲酯化、乙醚抽提、正己烷提取等3种方法对微拟球藻进行前处理,用索氏法提取油脂,经气相色谱分析,对比前处理方法对微拟球藻油脂提取率及脂肪酸组分的影响。结果表明:乙醚提取藻粉油脂的提取率(微藻的油脂质量分数)为12.70%,正己烷提取藻粉油脂的提取率为11.00%,乙醚提取油脂的提取率大于正己烷的提取率;直接甲酯化后测得微拟球藻脂肪酸中多不饱和脂肪酸(Polyunsaturated Fatty Acids,PUFAs)质量分数为20.04%,多不饱和脂肪酸中二十碳五烯酸(Eicosapentaenoic Acid,EPA)含量最丰富,占总脂肪酸13.0%;经过乙醚和正己烷提取后的油脂,脂肪酸组成更加简单,PUFAs含量明显增加,乙醚提取油脂EPA含量是直接甲脂化法的2.3倍,正己烷提取所得油脂EPA含量是直接甲脂化法的2.08倍。     

溶藻弧菌Ⅲ型分泌系统注射装置蛋白VscO的原核表达及免疫原性

为探究溶藻弧菌(Vibrio alginolyticus)ZJ03株Ⅲ型分泌系统(Type III secretion system,T3SS)注射装置蛋白VscO作为疫苗候选抗原的可能性,根据GeneBank上登陆的溶藻弧菌VscO序列(NO.KJ179947),设计1对带酶切位点的特异性引物,PCR扩增vscO基因,序列分析结果显示,该基因全长462 bp,理论分子质量为18.430ku。将vscO基因定向插入原核表达载体pET-28a(+),构建重组表达质粒pET-vscO。用异丙基-β-D-硫代半乳糖苷(IPTG)诱导后,可在大肠杆菌(Escherichia coli)BL21(DE3)中表达分子质量约为22 ku的VscO融合蛋白,且该蛋白主要以包涵体形式存在。VscO蛋白表达和纯化的最优条件为:0.1 mmol/L IPTG、37℃条件下诱导4 h,咪唑洗脱浓度为400 mmol/L。用纯化后的融合蛋白免疫SPF级小鼠,获得高效多克隆抗体。Western-blotting结果表明,鼠抗VscO血清既能与重组VscO蛋白发生反应,也能与分离自溶藻弧菌约22 ku的天然蛋白发生反应,提示T3SS注射装置蛋白VscO可能是溶藻弧菌的重要保护性抗原之一。     

重庆地区人体舒适度日数时空变化特征

利用1981-2010年重庆地区34个地面气象站资料日值数据集,基于人体舒适度指数模型和气候影响评价标准,综合采用线性回归、M－K突变、小波理论和EOF分析等方法分析人体舒适度日数时空分布特征。结果表明：重庆地区年平均人体舒适日数为199 d,主要舒适季节为春、秋季,占全年的71 %;人体舒适日数年际变化较大,总体呈上升趋势,存在4 a、7-8 a的周期振荡,其中热不舒适日数呈上升趋势,冷不舒适日数呈下降趋势;年平均人体舒适日数和热不舒适日数空间分布渝西南及渝东北日数较其他地区偏多,且存在季节性差异,而人体冷不舒适日数则相反。     

1961—2012年河南省夏季降水时空及环流特征

根据1961--2012年河南省111个气象观测站逐日降水资料,采用经验正交函数分解、小波分析等方法,研究了近52a河南省夏季降水的时空分布及环流特征。结果表明,河南夏季降水呈现从东南向西北减少的空间分布,淮河沿线为降水最多的区域,豫西和豫西北太行山一线为降水偏少区。全省夏季降水以全省偏多或偏少一致性为主,此外,还呈现南北反相、东西反相的分布特征。夏季降水存在多时间尺度的周期特征分布：在年代际变化尺度上,降水存在22a左右的周期,且在1977年后信号较强;年际变化尺度上以7a周期为主。在降水偏多年,中高纬存在一个东高西低的环流形势,有利于冷空气南下;低层有气旋式环流,高层有明显的东风环流,有利于水汽的聚集。在降水偏少年,环流形势相反,不利于夏季降水。