The BEAM-project: prediction and assessment of mixture toxicities in the aquatic environment

Freshwater and marine ecosystems are exposed to various multi-component mixtures of pollutants. Nevertheless, most ecotoxicological research and chemicals regulation focus on hazard and exposure assessment of individual substances only, the problem of chemical mixtures in the environment is ignored to a large extent. In contrast, the assessment of combination effects has a long tradition in pharmacology, where mixtures of chemicals are specifically designed to develop new products, e.g. human and veterinary drugs or agricultural and non-agricultural pesticides. In this area, two concepts are frequently used and are thought to describe fundamental relationships between single substance and mixture effects: Independent Action (Response Addition) and Concentration Addition. The question, to what extent these concepts may also be applied in an ecotoxicological and regulatory context may be considered a research topic of major importance, as the concepts would allow to make use of already existing single substance toxicity data for the predictive assessment of mixture toxicities. Two critical knowledge gaps are identified: (a) There is a lack of environmental realism, as a huge part of our current knowledge about the applicability of the concepts is restricted to artificial situations with respect to mixture composition or biological effect assessment. (b) The knowledge on what exactly is needed for using the concepts as tools for the predictive mixture toxicity assessment is insufficient. Both gaps seriously hamper the necessary, scientifically sound consideration of mixture toxicities in a regulatory context.In this paper, the two concepts will be briefly introduced, the necessity of considering the toxicities of chemical mixtures in the environment will be demonstrated and the applicability of Independent Action and Concentration Addition as tools for the prediction and assessment of mixture toxicities will be discussed. An overview of the specific aims and approaches of the BEAM project to fill in the identified knowledge gaps is given and first results are outlined.     

A Simplified Analytical Procedure for the Determination of Organically Bound Halogens in Salt‐containing Water Samples

A method was developed for the determination of organic halogens in water samples with the aim of minimizing matrix effects and simplifying the sample preparation technique commonly used. The method is based on the adsorption of organic halogens in modified hydrophilic divinylbenzene polymer columns and their elution with methanol. The adsorbent used enables rapid adsorption and desorption due to comparatively high operating flow rates and minimized solvent amounts. Furthermore, no additional reconcentration steps are needed. The methanol extract obtained is combusted with a standard EOX (extractable organic halogen) analyzer and the concentration of organically bound halogens is determined by microcoulometric analysis. The matrix effects are considerably reduced compared to the standard procedure (EN 1485) commonly used. A detection limit of 13 μg/L was established.     

一个中尺度流复合体的环境场、云场的特征分析

利用常规天气图、物理量诊断分析、逐时红外云图、单站资料等,对2003年4月12日影响鹰潭市的强对流、暴雨天气过程进行分析,认为该过程是在一定的大尺度环流背景下,由不同层次的天气系统共同作用下产生的;其触发机制是冷空气从近地层楔入暖空气中,在高、低空急流、层结不稳定等诸多有利条件下,由几个小尺度对流云团合并发展成1个中尺度对流复合体(MCC).     

振动采油工艺及增产效果分析

振动采油工艺是近两年研究开发的一种物理采油新工艺，尽管起步晚，增产机理还不清楚，但它的应用效果及推广前景引起了人们的关注和重视。本文就这一工艺研究开发进展情况作了概述，地增产效果进行了分析。     

Gaschromatographische Bestimmung von polychlorierten Biphenylen in Wasser nach Headspace-Festphasenmikroextraktion

Gas-chromatographic Determination of Polychlorinated Biphenyls in Water after Headspace Solid-phase Microextraction Headspace-analytical techniques are usually applied to the determination of easily volatile substances in water, whereas semivolatiles are generally isolated by liquid-liquid or solid-phase extraction. In the present paper, a method is presented for isolating high boiling polychlorinated biphenyls (PCB) using headspace solid-phase microextraction at elevated temperature. In spite of their low vapor pressure, the analytes are adsorbed very efficiently on a poly-dimethylsiloxane-coated fiber. Thus, in combination with GC/ECD, a very simple and sensitive solventless determination of PCB is accomplished. Using the simplest possible standard conditions, limits of determination in the lowest nanogram-per-liter range are achieved. Further increased sensitivity down to the ppq (parts per quadrillion) range is possible by stirring and increasing the sample volume and adsorption time. Moderate matrix effects have been observed in some surface and groundwaters.     

Toxic Cyanobacteria in Greek Freshwaters, 1987—2000: Occurrence,Toxicity, and Impacts in the Mediterranean Region

In a survey in Greece from 1987 to 2000 hepatotoxic cyanobacterial blooms were observed in 9 out of 33 freshwaters. Microcystins (MCYSTs) were detected by HPLC in 7 of these lakes, and the total MCYST concentration per scum dry weight ranged from 50.3 to 1638 ± 464 μg g^—1. Cyanobacterial genera (Microcystis, Anabaena, Anabaenopsis, Aphanizomenon, Cylindrospermopsis) with known toxin producing taxa were present in 31 freshwaters. From our data and a review of the literature, it would appear that Mediterranean countries are more likely 1) to have toxic cyanobacterial blooms consisting of Microcystis spp. and 2) to have higher intracellular MCYST concentrations. A case study in Lake Kastoria is used to highlight seasonal patterns of cyanobacterial and MCYST‐LR occurrence and to assess cyanotoxin risk. Cyanobacterial biovolume was high (> 11 μL L^—1) throughout the year and was in excess of Guidance Level 2 (10 μL L^—1) proposed by WHO for recreational waters and Alert Level 2 for drinking water. Further, surface water samples from April to November exceeded Guidance Level 3, with the potential for acute cyanobacterial poisoning. Intracellular MCYST‐LR concentrations (max 3186 μg L^—1) exceeded the WHO guideline for drinking water (1 μg L^—1) from September to November with a high risk of adverse health effects. Preliminary evidence indicates that in 3 lakes microcystins are accumulated in some aquatic organisms. Generally, a high risk level can be deduced from the data for the Mediterranean region.     

A size classification for debris flows

A 10-fold classification for debris flow size is proposed based on total volume, peak discharge and area inundated by debris. Size classes can be used for regional overview studies where detailed site investigations are either unnecessary, too costly or where the highest hazard and risk creeks need to be identified for further study. They are also useful to compare the regional impact between affected areas and the effects of rainstorms, and they allow lay-people to obtain an understanding of debris flow magnitude and consequences. Finally, different size classes allow the estimation of travel times to points of interest based on empirically derived equations. It is proposed that agencies concerned with debris flows should establish a documentation of debris flow size according to this classification, which serves as a data base for hazard and risk planning.     

Representing and communicating deep uncertainty in climate-change assessments

IPCC reports provide a synthesis of the state of the science in order to inform the international policy process. This task is made difficult by the presence of deep uncertainty in the climate problem that results from long time scales and complexity. This paper focuses on how deep uncertainty can be effectively communicated. We argue that existing schemes do an inadequate job of communicating deep uncertainty and propose a simple approach that distinguishes between various levels of subjective understanding in a systematic manner. We illustrate our approach with two examples. To cite this article: M. Kandlikar et al., C. R. Geoscience 337 (2005).     

中国高铁网络结构特征及其组织模式

基于2018年高铁网络OD数据,运用社会网络分析方法从高铁网络、城市节点等方面探讨中国城市高铁网络结构特征及其地域组织模式,结果表明:①中国高铁网络整体较为松散,东北地区网络密度最高,东部和中部地区作为整体网络的中介作用明显;②重要高铁线路的"廊道效应"突出,中心度呈现出以京广、京沪和沪昆高铁组成的"三角旗状"空间格局并向两侧城市呈不规则递减的态势;③多层级网络识别出紧密关联高铁线路和四横四纵向八横八纵格局的转变;④高铁网络的地域组织形式表现为点-轴串珠模式、双核组团模式和极核模式,高铁网络的完善使组织模式由单核趋向于网络化转变。