健脾解毒活血汤对幽门螺杆菌相关性胃炎脾胃湿热证模型小鼠IL-1β、GAS的影响

目的：观察健脾解毒活血汤对幽门螺旋杆菌相关性胃炎（HAG）脾胃湿热证模型小鼠血清白介素-1β（IL-1β）、胃泌素（GAS）及胃内组织Hp感染数的影响,为研制新型抗Hp感染的中药提供实验依据。方法：选取40只SPF级昆明小鼠为实验对象,将其随机分为空白组、模型组、西药组和中药组,每组各10只。采用Hp菌液灌胃以建立HAG脾胃湿热证小鼠模型,西药组予以奥美拉唑钠肠溶胶囊灌胃,中药组予以健脾解毒活血汤灌胃,均连续给药14d。观察比较各组小鼠血清IL-1β、GAS与胃内组织Hp感染情况。结果：模型组小鼠血清IL-1β、GAS的含量较空白组明显升高（P<0.01,P<0.05）;与模型组比较,中药组和西药组血清IL-1β显著降低（P<0.05,P<0.01）,GAS水平2组无明显差异。模型组小鼠胃组织Hp感染数较空白组明显增加（P<0.01）,中药组和西药组胃组织Hp感染数较模型组显著降低（P<0.05）。结论：健脾解毒活血汤对HAG脾胃湿热证模型小鼠血清IL-1β及Hp感染数有明显改善作用,但对GAS影响不大,在一定程度上可有效治疗脾胃湿热型HAG。     

集成虚拟格网和八叉树的点云数据管理方法

为实现大规模点云的快速组织和检索,提出了基于内外存动态调度的虚拟格网与八叉树相结合的点云数据索引和组织策略。该方法利用虚拟格网对点云进行节点分割和存储,并结合磁盘映射与内外存动态调度技术,将节点进行构八叉树以实现点云数据高效的组织与检索。实验证明,该方法可在计算机内存资源有限的情况下,以较小的内存消耗实现十亿级规模点云的快速组织和检索操作。     

基于Zemax外海观测光纤探针传感器探头结构的优化设计

光纤探针法是一种适合观测波浪破碎瞬间卷入微气泡羽流的方法,现有的观测探针探头多采用塑料、玻璃等材质,存在脆性大、损耗大、不耐低温、易腐蚀等缺点,拟设计一种蓝宝石光纤探针克服其局限性,提升探测性能.文章在介绍光纤探针传感器测量原理的基础上,采用光学仿真软件Zemax建立了光纤探针传感器探头的仿真模型,并利用模型对其每针的材质、形状、角度等结构设计关键因素进行了优化设计,由仿真结果确定了每针形状为圆锥形、传输材质为蓝宝石.该仿真结果将为后续光纤探针传感器系统的整体设计及光路优化奠定基础.     

不同形状振荡浮子入水冲击的实验研究

振荡浮子在波浪能转换装置中应用非常广泛,在其服役期间,由于较小的设计吃水深度或为防避极端海况的需要,它们经常会离开水面;当其再次入水的时候,浮子底部就会受到入水冲击。入水冲击总是伴随着巨大的冲击压强以及冲击载荷,会导致浮子的结构性及疲劳性破坏,从而影响浮子的工作寿命。本文对锥形、半球形和横圆柱形三种形状的浮子入水冲击过程进行了实验研究,分析了浮子表面压强和冲击加速度的变化规律。主要结论如下:(1)在巨大的水阻力作用下,入水瞬间三种浮子表面压强急剧上升,迅速达到最高峰值;之后由于空气垫的作用,压强出现二次峰值现象。(2)在空气垫的作用下,三种浮子的最高压强峰值均未出现在浮子的最低点处,而是出现在外围某处。(3)三种浮子在触水瞬间的加速度均达到hm/s~2的量级,而后急剧下降,并在较短时间内达到一平衡值并沿其小幅震荡。(4)横圆柱形浮子由于其非垂直轴对称性,其表面压强和加速度的震荡更加明显。     

基于破碎临界区的新型拍岸浪统计计算模型研究

When waves propagate from deep water to shallow water, wave heights and steepness increase and then waves roll back and break. This phenomenon is called surf. Currently, the present statistical calcula...     

海洋环境数据在线服务系统设计与实现

文章针对海洋数据信息孤岛、服务对象单一等问题,设计了海洋环境数据在线服务系统。采用并行数据库技术实现数据的快速组织整理、查询检索,解决数据高耦合、高冗余等问题,提高对数据的快速检索能力。利用虚拟化技术完成存储、服务器、网络设备资源整合与集群建设,解决物理设备分布散乱、利用率低的问题,提高资源利用率,节约成本。利用域控管理机制,实现系统信息安全与数据在线服务。     

基于近岸GPS RTK技术的潮位和波浪提取算法研究

由于潮汐和波浪的周期相差甚远,对实时海面高程数据进行相应的低通和带通滤波即可提取潮位和波浪信息。通过对仿真的实时海面高程数据进行平滑滤波、中值滤波、小波滤波等低通滤波,以及椭圆、巴特沃斯等带通滤波结果分析表明:近岸GPS RTK技术可用于潮位和波浪同步测量;对于潮位信息的提取方面,平滑、中值、小波等低通滤波均能很好的提取出潮位信息,其中平滑滤波最佳,且工程中易于实现;对于波浪信息的提取方面,椭圆滤波、巴特沃斯、切比雪夫Ⅰ型等带通滤波均能很好提取出波浪信息。     

A Bingham-plastic model for fluid mud transport under waves and currents

Simplified equations of fluid mud motion, which is described as Bingham-Plastic model under waves and currents, are presented by order analysis. The simplified equations are non-linear ordinary differential equations which are solved by hybrid numerical-analytical technique. As the computational cost is very low, the effects of wave current parameters and fluid mud properties on the transportation velocity of the fluid mud are studied systematically. It is found that the fluid mud can move toward one direction even if the shear stress acting on the fluid mud bed is much smaller than the fluid mud yield stress under the condition of wave and current coexistence. Experiments of the fluid mud motion under current with fluctuation water surface are carried out. The fluid mud transportation velocity predicted by the presented mathematical model can roughly match that measured in experiments.     

Numerical simulation and experimental research on hydrodynamic performance of propeller with varying shaft depths

In order to study hydrodynamic performance of a propeller in the free surface, the numerical simulation and open-water experiments are carried out with varying shaft depths of propeller. The influences of shaft depths of a propeller on thrust and torque coefficient in calm water are mainly studied. Meanwhile, this paper also studies the propeller air-ingestion under special working conditions by experiment and theoretical calculation method, and compares the calculation results and experimental results. The results prove that the theoretical calculation model used in this paper can imitate the propeller air-ingestion successfully. The successful phenomenon simulation provides an essential theoretical basis to understand the physical essence of the propeller air-ingestion.     

Design of a hydraulic power take-off system for the wave energy device with an inverse pendulum

This paper describes a dual-stroke acting hydraulic power take-off （PTO） system employed in the wave energy converter （WEC） with an inverse pendulum. The hydraulic PTO converts slow irregular reciprocating wave motions to relatively smooth, fast rotation of an electrical generator. The design of the hydraulic PTO system and its control are critical to maximize the generated power. A time domain simulation study and the laboratory experiment of the full-scale beach test are presented. The results of the simulation and laboratory experiments including their comparison at full-scale are also presented, which have validated the rationality of the design and the reliability of some key components of the prototype of the WEC with an inverse pendulum with the dual-stroke acting hydraulic PTO system.