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Endocrine disrupting chemicals (EDCs) are increasingly viewed as persistent pollutants, similar to natural hormones in function. This paper describes the expression profiles of 7 genes (DMRT, VTG, GnRHR, FSHR, CYP17A, CYP19A, and CYP19B) involved in sex steroid synthesis and action as well as sexual development in adult male and female Cynoglossus semilaevis, after exposure to different concentrations of Bisphenol A (BPA) and 17β-estradiol (E2). Both BPA (1, 10, 50, 125, and 250 mg/kg) and E2 (0.5, 5, and 10 mg/kg) induced changes in target gene expression, although the estrogenic effects of E2 as a model estrogen were stronger. Among the 7 genes, VTG, CYP17A and CYP19 responded strongly to BPA or E2 exposure and can thus serve as reference biomarkers for estrogenic EDCs exposure in marine teleosts. These data will provide a window to establish a hypothalamic-pituitary-gonadal model in C. semilaevis to better understand the effect pathways of EDCs. 相似文献
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热带气旋过境期间黑潮流轴变化的初步分析 总被引:1,自引:0,他引:1
利用卫星高度计资料分析了热带气旋"艾碧"(Abe,9315)、"贝姬"(Becky,9316)、"莫拉克"(Morakot,0309)和"茉莉"(Melor,0319)对吕宋海峡及其附近海域黑潮流轴的影响。研究表明:1)吕宋海峡附近海域黑潮流轴容易受到热带气旋的影响而发生一定的变化。2)在热带气旋的作用下,黑潮流轴因中尺度涡的变异而变化;当吕宋海峡东侧的暖涡西移时,将使黑潮的流轴向西弯曲,有利于黑潮在该处的入侵。 相似文献
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Paul Sava 《Geophysical Prospecting》2012,60(1):29-48
Seismic waves propagate through the earth as a superposition of different wave modes. Seismic imaging in areas characterized by complex geology requires techniques based on accurate reconstruction of the seismic wavefields. A crucial component of the methods in this category, collectively known as wave‐equation migration, is the imaging condition that extracts information about the discontinuities of physical properties from the reconstructed wavefields at every location in space. Conventional acoustic migration techniques image a scalar wavefield representing the P‐wave mode, in contrast to elastic migration techniques, which image a vector wavefield representing both the P‐ and S‐waves. For elastic imaging, it is desirable that the reconstructed vector fields are decomposed into pure wave modes, such that the imaging condition produces interpretable images, characterizing, for example, PP or PS reflectivity. In anisotropic media, wave mode separation can be achieved by projection of the reconstructed vector fields on the polarization vectors characterizing various wave modes. For heterogeneous media, because polarization directions change with position, wave mode separation needs to be implemented using space‐domain filters. For transversely isotropic media with a tilted symmetry axis, the polarization vectors depend on the elastic material parameters, including the tilt angles. Using these parameters, we separate the wave modes by constructing nine filters corresponding to the nine Cartesian components of the three polarization directions at every grid point. Since the S polarization vectors in transverse isotropic media are not defined in the singular directions, e.g., along the symmetry axes, we construct these vectors by exploiting the orthogonality between the SV and SH polarization vectors, as well as their orthogonality with the P polarization vector. This procedure allows one to separate all three modes, with better preserved P‐wave amplitudes than S‐wave amplitudes. Realistic synthetic examples show that this wave mode separation is effective for both 2D and 3D models with strong heterogeneity and anisotropy. 相似文献
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AbstractShort waste fibers are used to suppress the expansion and improve the tensile strength of cement-stabilized marine clay (CMC). The fiber-reinforced mechanism and characteristics are revealed by experimental and numerical methods. First, the curing effect of the CMC when adding a composite curing agent is observed by scanning electronic microscopy, as is the contact surface between the fiber and the matrix. Then, the expansion rate and the tensile strength of fiber-reinforced cement-stabilized marine clay (FCMC) are illustrated by an expansion experiment and a direct tensile experiment, respectively. The results show that the sample with the cement content of 0.1% and the fiber length of 10?mm is the best in terms of strength enhancement and expansion inhibition. Finally, the mechanism of fiber reinforcement is discussed following a single fiber pullout experiment and some comprehensive explanations are proposed to verify the results of the tensile experiment. A numerical simulation of a single fiber pullout from a matrix is established by using a cohesive contact model. The comparison between the numerical results and the experimental results shows that the two models can be in good agreement, indicating that the calculation model of the interaction between the fiber and the matrix is realistic. 相似文献