Mathematical Models for Combined Refraction-Diffraction of Waves on Non-Uniform Current and Depth

Two mathematical models for combined refraction-diffraction of regular and irregular waves on non-uniform current in water of slowly varying topography are presented in this paper. Model I is derived by wave theory and variational principle separately. It has two kinds of expressions including the dissipation term. Model n is based on the energy conservation equation with energy flux through the wave crest lines in orthogonal curvilinear coordinates and the wave kinematic conservation equation. The analysis and comparison and special cases of these two models are also given.     

基于网络药理学-分子对接探索大黄牡丹汤治疗大肠癌的作用机制

目的：利用网络药理学-分子对接技术探索经方大黄牡丹汤治疗大肠癌的作用机制。方法：通过TCMSP、TCMID数据库获得大黄牡丹汤药物成分,通过PubChem、Swisstarget prediction数据库获得药物成分对应靶点,分析GSE113513芯片获得差异基因,随即获取大黄牡丹汤与大肠癌的共同靶点。利用R、Cytoscape、Autodock软件进行PPI、GO、KEGG、分子对接等分析。结果：获得大黄牡丹汤靶点561个,大肠癌差异基因1227个,共同靶点71个。共同靶点的通路富集分析显示主要与PPAR、p53等信号通路相关,Reactome机制分析显示大黄牡丹汤治疗大肠癌主要通过影响信号转导、免疫系统、疾病等产生作用,分子对接结果显示大肠癌核心靶点与大黄牡丹汤主要成分亲和力较好,能够有效自由结合。结论：经方大黄牡丹汤可通过多层次、多途径、多靶点发挥对大肠癌的治疗作用。     

Ancient and modern cold-climate aeolian sand deposition: A review

Although partly active aeolian sand sheets and dunes cover large areas in the zones of (dis)continuous permafrost, little precise information is available about the influence of cold-climate conditions on modern aeolian processes. This means that palaeoenvironmental reconstructions in the stabilised, mainly Late Pleistocene dune fields and cover sand regions in the ‘sand belts’ of the European Lowlands and the Northern Great Plains of the USA and Canada, are necessarily still based on ancient evidence. Cold-climate wind deposits are typically derived from areas of abundant sediment supply like unvegetated flood plains, glacial outwash plains, till plains and lake shores. The common parabolic and transverse dune forms resemble those observed in temperate regions. Although a variety of periglacial features has been identified in Late Pleistocene dune and cover sands none of them indicate that permafrost is crucial to aeolian activity. Specific structures in aeolian strata permit tentative interpretation of the moisture content of depositional sand surfaces, the nature of annual sedimentation cycles and the processes by which strata were deposited and/or contorted. But surprisingly little is known about the role of vegetation in the process of sand accumulation. Dunes are most informative with respect to reconstructions of past wind regimes, which offer important data for verification of palaeoclimatic simulations.     

波浪作用下单桩基础周围海床液化机制研究

建立波浪作用下单桩周围三维海床动力响应模型,考虑自重影响下的海床长时间固结过程。采用已有物理模型试验数据对模型进行验证,证实其具有较好的适用性。模拟波浪作用下单桩周围三维海床液化区域,通过定量分析超孔隙水压力和土体初始有效应力的变化,讨论单桩插入深度对海床液化的影响机制。研究表明,单桩插入深度发生变化时,土体初始有效应力对海床液化的影响要大于超孔隙水压力,且影响程度随着插入深度的增加而逐渐增大。     

低聚羧甲基壳聚糖的抗氧化性能

将低聚壳聚糖(chitosan oligosaccharide,COS)醚化得到O-羧甲基壳聚糖(O-carboxymethyl chito-sanolig osaccharide,O-CMCOS)和N-羧甲基壳聚糖(N-carboxymethyl chitosanolig osaccharide,N-CMCOS),其取代度(substituting degree,DS)均为0.54,用红外光谱对其结构进行表征。同时,考察了其结构对超氧阴离子的清除活性以及还原能力。结果表明,COS及其衍生物清除超氧阴离子的活性及还原能力的强弱顺序均为:O-CMCOSCOSN-CMCOS。     

墨西哥湾南部晚侏罗纪主力烃源岩的形成条件

通过对墨西哥湾不同时代可采储量的分布特征和油源对比资料的分析认为,晚侏罗纪烃源岩是墨西哥湾南部最主要的烃源岩。资料显示,晚侏罗纪优质烃源岩形成的主控因素是稳定的构造和沉积条件以及超咸的还原环境,其中,"世界顶级"的晚侏罗纪提塘阶烃源岩主要形成于超咸的碳酸盐岩和/或蒸发岩沉积环境,属半深海还原环境,有机质以藻类为主,推测烃源岩中的有机质可能与极端干旱气候条件下的藻类勃发有关。     

水平地震作用下无锚固储罐应力与应变响应分析

在考虑地基与储罐相互作用的情况下,采用有限元法对储罐在水平地震荷载作用下的应力及应变反应进行了数值计算。对3×104m3和2×103m3罐壁应力及应变的分析结果表明:环向、轴向应力及应变的分布形式呈现出明显的下部大上部小的特点,在偏底部的位置出现应力和应变的峰值;储液罐在水平地震作用下“象足”变形是由纵向压应力达到屈曲临界应力导致的屈曲破坏,不是强度破坏,即破坏属于失稳破坏而非强度破坏。     

扬子板块西缘攀西地区白草矿区黄铁矿标型元素特征及其指示意义

黄铁矿是重要的金属硫化物矿物,在多种矿床中均有产出,其标型特征对矿床成因、矿体空间分布等具有重要的指示意义.以扬子板块西缘攀西地区白草矿区黄铁矿为研究对象,利用矿相学、电子探针等分析方法来对比研究浸染状、致密块状、斑杂状、网脉状矿石中黄铁矿的标型元素特征.结果表明:白草矿区黄铁矿Fe、S平均含量(质量分数,下同)分别为...     

冀中拗陷古潜山油田水化学研究

冀中拗陷油气田87%的储量产于海相碳酸盐岩古潜山中,在油气生成、运移、集聚和散失的过程中地下水起了重要作用。本文根据50个试样的水化学分析资料,运用对应分析方法对冀中拗陷古潜山油田水进行了分类并初步探讨了水化学成分演化与油气藏形成的关系。     

Rayleigh 阻尼作用下斜拉桥扭转振动

在侧向风力或侧向水平地源力作用下,斜拉桥容易发生扭转振动。本文采用非线性Rayleigh阴尼,它能反映在低速振动时有激发而加速振动,至一定高速后又衰减的完整振动过程。对非线性的统辖方程及定解条件,先使之无量纲化,再按非线性项的系数这个小参数展开未知函数,得到线性化的各级近似方程。把待求函数展成梁轴坐标的Fourier级数,其系数为待定的时间函数,应用Fourier级数的正交性,得到求解未知时间函数的二阶常微分方程,完全类似单自由度质点在线性粘滞性阻尼作用下的统辖方程,其解为已知。