Researches on the Internal Molecular Weight Uniformity of Chitosan Biomaterials

Uniform molecular weight(Mw)chitosan(CS)is highly demanded in medical biomaterial industry.This present article described heterogeneous degradation of CS in aqueous HCl/ethanol solution,in which progress uniform Mw CS was successfully prepared.The Mw distribution of CS was measured by gel permeation chromatography(GPC)analysis.Moreover,the structure and properties of degraded CS were characterized by Fourier transform infrared spectroscopy(FT-IR),nuclear magnetic resonance spectroscopy(^1H NMR),X-ray diffraction(XRD)and thermogravimetric(TG)analysis.In addition,the biocompatibility of degraded CS was also assessed by hemolysis rate(HR)measurement.The Mw of CS dramatically decreased from 246 KDa to 76 k Da at the initial 30 min,and stabilized at 18 kDa after 24 h.GPC analysis results showed that the degraded CS molecular become homogenization.FT-IR and 1 H NMR analysis confirmed the basic structure of CS molecular backbone was not destroyed during this progress.Besides,the water solubility of CS was not significantly influenced by this reaction.Moreover,the XRD analysis revealed that crystallinity of degraded CS increased from 70.32% to 99.25%with time.The TG analysis showed improved thermal stability of degraded CS.HR measurement demonstrated the degraded CS possessed excellent biocompatibility.This simple and efficient heterogeneous degradation would open up a new route to produce uniform Mw CS.     

分布式社区口腔医疗信息管理系统设计

利用SQL Server和VB设计分布式社区口腔医疗信息管理系统,建立牙科电子病历,实现远程医疗信息共享和IC卡一卡通服务,改善口腔医疗服务水平.     

城市医疗设施空间分布合理性评估

随着经济发展和人民生活水平的不断提高,城市居民对健康的重视程度不断的增加,医疗设施作为城市中不可或缺的公共设施发挥着越来越重要的作用。城市的不断扩张导致医疗机构的分布已不能适应当前的城市规模,如何能够将有限的医疗资源进行合理的分配,并能在最大程度上满足居民的需求成为当下研究热点。本研究基于地理信息系统（GIS）空间分析技术,根据统计资料建立武汉市中心城区交通网络、医疗机构分布、人口等数据库,分别从可达性和公平性角度评价武汉市医疗设施的空间分布合理性,并利用地理空间可达性评估法和基于交通网络行进时间成本法分别对武汉市中心城区医疗设施可达性进行评价。就医可达性评估显示,武汉市居民就医便捷程度总体上较好,并以长江和汉江的交界地区为中心,呈四周放射状分布。通过引入需求指数、医疗机构规模、区域人口、人均可支配收入等指标,利用基尼系数、空间相关性和空间分层异质性评价医疗服务设施空间分布公平性。结果表明,武汉市医疗机构分布按人口分布合理,医疗机构主要集中分布在人口密集的主城区;地理分布上城郊地区医疗机构相对稀少。最后,依据可达性和公平性评价结果,对武汉市医疗设施布局提出合理化建议。在城市规划发展中,应更多考虑改善郊区等交通欠发达区域居民的就医条件,从而完善城市医疗设施分布。     

The journal Communications in Numerical Methods in Engineering with Biomedical Applications becomes the International Journal for Numerical Methods in Biomedical Engineering (IJNMBE) from 1st January 2010

Communications in Numerical Methods in Engineering, founded by Roland W. Lewis in 1985, will change its title to the ‘International Journal for Numerical Methods in Biomedical Engineering’ and has a revised Aims and Scope. Copyright © 2009 John Wiley & Sons, Ltd.     

Equal strain consolidation for stone columns reinforced foundation

Column consolidation and deformation are considered by assuming that the quantity of water flowing through the disturbed soil zone into the column is not equal to that flowing out from the column and the difference between them is equal to the volume change of the column. In addition, three patterns of distribution of the horizontal permeability of soil in the disturbed zone are also considered to account for the disturbance effect of columns construction on the surrounding soil. These three patterns include the constant distribution pattern (Pattern I), the linear distribution pattern (Pattern II) and the parabolic distribution pattern (Pattern III). By incorporating the aforementioned characteristics into the analyses, the governing equations containing two variables (i.e. the average excess pore-water pressures within the column and within the entire foundation at any depth) for the consolidation of a composite foundation are derived. The solutions of the governing equations are then obtained using a new initial condition derived from the assumption of equal strain and the equilibrium condition. On the basis of the solutions for excess pore-water pressures, the average degree of consolidation of a composite foundation is obtained and discussed. Finally, a comparison is made of some available solutions. Copyright © 2009 John Wiley & Sons, Ltd.     

北京地区细菌性痢疾医疗气象预报模式及流行风险水平评估

研究了北京市海淀区2004～2006年全年逐日细菌性痢疾发病率与地面气象要素的相关关系.结果发现,细菌性痢疾发病与水汽压(空气绝对湿度)高度相关,单相关系数平均可达0.85以上.在所有候选预报因子中,它的方差贡献可占80%.采用多元回归概率分级技术,建立了细菌性痢疾医疗气象预报及风险水平评估模式.该模式预报结果可为各级疾病预防控制中心指导广大城乡居民卫生防疫提供科学依据.     

西安地热田医疗热矿水的产出状况分析

本文介绍了西安地热田概况及开采现状, 重点讨论了西安地热田医疗热矿水的产出状况     

沂南冯家村瓷石资源及其矿床地质特征

冯家村瓷石矿赋存于中生代燕山晚期中细斑二长花岗斑岩中,系酸性浅成侵入岩矿床。矿石化学成分高硅、富碱、贫铁镁,矿石工业类型属硬质瓷石,矿床成因为岩浆型矿床。矿体出露地表,规模大、质量优,易于开采。该矿床不仅为山东省陶瓷产业发展提供了资源保障,而且对寻找同类型瓷石矿床具有重要的现实指导意义。     

青岛市崂山风景区崩塌地质灾害治理方法探讨——以大平岚崩塌人造景观石治理为例

青岛市崂山风景区旅游主线大平岚附近发生崩塌地质灾害,导致崂山风景区南线道路全线封闭,崩落巨石上方的残留危岩体存在严重安全隐患,急需治理。为使原有景观石得以保护,又不致于形成新的视觉污染,利用人造景观石在崂山风景区大平岚崩塌地质灾害治理工程中进行了探索。实践证明,该方案投资少、工期短、效果好,既消除了崩塌地质灾害隐患,使原有景观石得到了保护,又未形成新的视觉污染,为人造景观石在风景区地质灾害治理工程中的应用起到了示范作用。     

山东省天然饰面石材花岗石和大理石地质特征及其分类

山东省天然饰面石材资源储量大,天然饰面石材品种多,地质成因和地质特征各有不同。通过天然饰面石材的岩石学特征对山东省天然饰面石材进行分类总结,从天然饰面石材的岩石学和矿物学角度出发,归纳山东省天然饰面石材的地质特征。通过对山东省典型天然饰面石材进行分类列举,归纳山东省典型天然饰面石材的地质特征。