Low-frequency damping of a moored semisubmersible obtained from simulated extinction tests and mean wave drift forces

Low-frequency damping of a moored semisubmersible drilling platform was obtained from numerical extinction tests simulated in still water and in regular waves and from mean wave drift forces calculated at zero forward speed. The influence of drag forces was represented by the modified Morison equation. The platform as used for the 18th ITTC Comparative Mooring Study was analyzed in irregular beam waves. The computed time series of sway as well as the corresponding sway response spectrum compared favourably with model test measurements, demonstrating that this procedure to determine low-frequency damping can be effective.     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

回收法治理锯条厂氰化物污水

在采用回收法治理锯条厂氰化物污水中，通过改造生产工艺，减少污水量，提高氰化物浓度及污水经除油后减压蒸馏，可回收５０％～９０％的氰化铂，其他盐分也可全部回收，从污水中蒸出的蒸馏水能在系统内循环使用。     

Small-scale variability of zooplankton pyruvate kinase activity in the Gironde Estuary plume (Atlantic French Coast): A case study under unusually low freshwater discharge

Pyruvate kinase (PK) activity measurements are used to assess the role of carbohydrates in global feeding of mesozooplankton communities inhabiting an estuary plume. As a consequence of a remarkably low freshwater discharge rate, the sea surface layers of the area under estuarine influence showed a very moderate salinity fall and a nearly total depletion in nitrates, whereas higher levels of these nutrients were found in deeper, more saline, layers. Small-scale PK activity variations in mesozooplankton appear to be closely correlated to nitrate integration values within the water column. The results were analysed in comparison with literature reports. The study produced a coherent overall interpretation, which strongly supports the reliability of this new biochemical tool in detecting assimilation of trace carbohydrates in the diet of mesozooplankton.     

基于圆特征的地图要素自动综合算法研究

分析了目前地图综合的地位、作用和发展情况,介绍了“优胜劣汰”思想,分析对比出自然界“优胜劣汰”基本思想和地图制图综合在某些方面存在共同的相似之处,从而尝试把它运用到地图制图综合中来,并结合Circle技术及其基本特点,提出了基于Circle原理和“优胜劣汰”思想的地图综合新算法,在地图综合的选取、化简、合并等方面得到了较好的应用,相应的例子在文中详细地进行了列举。     

任意曲线曲面上重磁位场转换的B样条函数法

提出用B样条函数求解曲线、曲面上重磁位场的向上延拓,水平、垂向导数计算,磁异常分量互换的方法。该方法的特点是:原理简明,程序通用性强,计算精度高。