Roles of Continental Shelves and Marginal Seas in the Biogeochemical Cycles of the North Pacific Ocean

Most marginal seas in the North Pacific are fed by nutrients supported mainly by upwelling and many are undersaturated with respect to atmospheric CO₂ in the surface water mainly as a result of the biological pump and winter cooling. These seas absorb CO₂ at an average rate of 1.1 ± 0.3 mol C m⁻²yr⁻¹ but release N₂/N₂O at an average rate of 0.07 ± 0.03 mol N m⁻²yr⁻¹. Most of primary production, however, is regenerated on the shelves, and only less than 15% is transported to the open oceans as dissolved and particulate organic carbon (POC) with a small amount of POC deposited in the sediments. It is estimated that seawater in the marginal seas in the North Pacific alone may have taken up 1.6 ± 0.3 Gt (10¹⁵ g) of excess carbon, including 0.21 ± 0.05 Gt for the Bering Sea, 0.18 ± 0.08 Gt for the Okhotsk Sea; 0.31 ± 0.05 Gt for the Japan/East Sea; 0.07 ± 0.02 Gt for the East China and Yellow Seas; 0.80 ± 0.15 Gt for the South China Sea; and 0.015 ± 0.005 Gt for the Gulf of California. More importantly, high latitude marginal seas such as the Bering and Okhotsk Seas may act as conveyer belts in exporting 0.1 ± 0.08 Gt C anthropogenic, excess CO₂ into the North Pacific Intermediate Water per year. The upward migration of calcite and aragonite saturation horizons due to the penetration of excess CO₂ may also make the shelf deposits on the Bering and Okhotsk Seas more susceptible to dissolution, which would then neutralize excess CO₂ in the near future. Further, because most nutrients come from upwelling, increased water consumption on land and damming of major rivers may reduce freshwater output and the buoyancy effect on the shelves. As a result, upwelling, nutrient input and biological productivity may all be reduced in the future. As a final note, the Japan/East Sea has started to show responses to global warming. Warmer surface layer has reduced upwelling of nutrient-rich subsurface water, resulting in a decline of spring phytoplankton biomass. Less bottom water formation because of less winter cooling may lead to the disappearance of the bottom water as early as 2040. Or else, an anoxic condition may form as early as 2200 AD. This revised version was published online in July 2006 with corrections to the Cover Date.     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

城市建设中的地震小区划与浅层地震探测

简要阐述地震小区划在现代城市建设中的重要性以及在实施地震小区划的研究中浅层地震探测的重要作用及其方法原理,并给出应用浅层地震探测在城市地震小区划中的实例。     

关于修改港工钢筋混凝土规范小偏心受压构件正截面强度计算的建议

本文提出在小偏心受压构件正截面强度计算中，取消弯曲抗压强度ｆｃｍ（Ｒｗ），采用轴心抗压强度ｆｃ，这与构件的实际破坏形态相符。对小偏心受压构件正截面强度计算提出了设计建议。特别是对工程上大量应用的矩形截面对称配筋小偏压构件提示了简捷的设计方法，与以往的近似计算方法相比具有物理概念明确，精度高，方法简捷的特点。     

Regulation of Navigation Channel on Mouth Bar of Guanhe Estuary

-Based on the feasibility study of developing the navigation resources of the Guanhe River and the model test results of the mouth bar regulation, this paper presents some basic principles for the regulation of the channel on the mouth bar, for instance, the direction of navigation channel should be identical with that of the ebb tide current and the main waves, and perpendicular to the bathymetric contours. The principles for regulating mouth bars are also discussed in this paper.     

高速摄影对散体振动的研究

以现代高速摄影技术和图像分析以及数据处理方法，针对高效振动磨机中弹性散体工质（如钢棒、球体等）的振动力学进行了深入的探讨和分析，为研究散体动力学和振动超细粉碎过程中的能量分布和传递规律以及能量与物质的相互转换机理奠定了基础，也为相关学科的发展提供了一种可以借鉴的方法。     

六溴苯的合成研究

对直接溴化法合成六溴苯作了系统的研究,并对文献方法进行了一系列的改进。包括选择适当的摧化剂及其用量,使反应基本上在室温下进行;利用水汽蒸馏法驱除残余溴,可直接得到无色或近乎无色的纯净产物,而勿需进行还原脱溴,且得率较高。提出一种以溴化物形式回收副产物的方法。     

热带气旋活动对中国夏季雨带类型与ENSO的响应关系

本文分析研究了热带气旋１）活动与中国夏季２）３组（包括８种）主要多雨带类型的响应关系。同时对热带气旋活动与夏季大陆气温和ＥＮＳＯ事件的始终时间的响应关系，也进行了探讨。分析表明，夏季中国的雨带分布特征对热带气旋活动有着十分重要的指示意义。热带气旋活动与中国大陆气温有着正相关关系，与ＥＮＳＯ事件的发生有着反相关关系     

辽河盆地大民屯凹陷流体压力特征

大民屯凹陷是辽河断陷内4个下第三系凹陷之一。在综合利用钻井、试井及地震等资料的基础上，系统研究并论述了大民屯凹陷流体压力特征。基于57口井的声波测井资料，凹陷内泥岩压力特征可区分为正常压力、异常压力或强超压等类型；根据152口井391个点的压力测试数据，凹陷内产油层段的压力梯度多接近于1；利用公式法模拟计算了47条地震剖面的流体压力、剩余压力及压力系数的分布特征，凹陷内剖面压力系统自上而下一般由正常压力、弱超压和强超压3部分组成。此外，还根据流体压力演化的基本原理及钻井、岩性与试井等实际资料，模拟恢复了大民屯凹陷的压力演化史，其可划分为超压原始积累、超压部分释放及超压再积聚3个阶段。总体上，大民屯凹陷的超压强度低于渤海湾盆地其他地区的超压强度。